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PLL [cytosol]
Stable Identifier
R-DME-206070
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Drosophila signaling pathways (Drosophila melanogaster)
Toll pathway (Drosophila melanogaster)
Degradation of NF-kappa-B inhibitor, CACT (Drosophila melanogaster)
Activated PLL kinase is autophosphorylated in the TL receptor 'signalling complex' (Drosophila melanogaster)
Activated PLL kinase is autophosphorylated in TL:MYD88:TUB:PLL 'signalling complex' (Drosophila melanogaster)
PLL [cytosol] (Drosophila melanogaster)
SPZ dimer:TL dimer:SPZ dimer:MYD88:TUB:PLL [plasma membrane] (Drosophila melanogaster)
PLL [cytosol] (Drosophila melanogaster)
Activated PLL kinase is autophosphorylated in TL:WEK:MYD88:TUB:PLL 'signalling complex' (Drosophila melanogaster)
PLL [cytosol] (Drosophila melanogaster)
SPZ dimer:TL dimer:SPZ dimer:PLL:MYD88:TUB:WEK dimer:MYD88:TUB:PLL [plasma membrane] (Drosophila melanogaster)
PLL [cytosol] (Drosophila melanogaster)
SPZ dimer:TL dimer:SPZ dimer:PLL:MYD88:TUB:WEK dimer:MYD88:TUB:Phospho PLL [plasma membrane] (Drosophila melanogaster)
PLL [cytosol] (Drosophila melanogaster)
DL and DIF homodimers bind to TUB and phosphorylated PLL in the TL receptor 'signalling complex' (Drosophila melanogaster)
DL dimer binds to TUB and phosphorylated PLL in TL:WEK:MYD88:TUB:PLL 'signalling complex' (Drosophila melanogaster)
SPZ dimer:TL dimer:SPZ dimer:PLL:MYD88:TUB:WEK dimer:MYD88:TUB:Phospho PLL [plasma membrane] (Drosophila melanogaster)
PLL [cytosol] (Drosophila melanogaster)
SPZ dimer:TL dimer:SPZ dimer:PLL:MYD88:TUB:WEK dimer:MYD88:TUB:Phospho PLL:DL dimer:CACT [plasma membrane] (Drosophila melanogaster)
PLL [cytosol] (Drosophila melanogaster)
DL and DIF homodimers complexed with CACT are all phosphorylated in the TL receptor 'signalling complex' (Drosophila melanogaster)
CACT and DL dimer are phosphorylated in TL:WEK:MYD88:TUB:PLL 'signalling complex' (Drosophila melanogaster)
SPZ dimer:TL dimer:SPZ dimer:PLL:MYD88:TUB:WEK dimer:MYD88:TUB:Phospho PLL:DL dimer:CACT [plasma membrane] (Drosophila melanogaster)
PLL [cytosol] (Drosophila melanogaster)
SPZ dimer:TL dimer:SPZ dimer:PLL:MYD88:TUB:WEK dimer:MYD88:TUB:Phospho PLL:Phospho DL dimer:Phospho CACT [plasma membrane] (Drosophila melanogaster)
PLL [cytosol] (Drosophila melanogaster)
Phosphorylated CACT, DL and DIF homodimers dissociate from the TL receptor 'signalling complex' (Drosophila melanogaster)
Phosphorylated CACT and DL dimer dissociate from the TL:WEK:MYD88:TUB:PLL 'signalling complex' (Drosophila melanogaster)
SPZ dimer:TL dimer:SPZ dimer:PLL:MYD88:TUB:WEK dimer:MYD88:TUB:Phospho PLL [plasma membrane] (Drosophila melanogaster)
PLL [cytosol] (Drosophila melanogaster)
SPZ dimer:TL dimer:SPZ dimer:PLL:MYD88:TUB:WEK dimer:MYD88:TUB:Phospho PLL:Phospho DL dimer:Phospho CACT [plasma membrane] (Drosophila melanogaster)
PLL [cytosol] (Drosophila melanogaster)
Formation of the trans-membrane 'signalling complex' (Drosophila melanogaster)
PLL kinase binds to TUB in the TL receptor 'signalling complex' (Drosophila melanogaster)
PLL kinase binds to TL:MYD88:TUB 'signalling complex' (Drosophila melanogaster)
PLL [cytosol] (Drosophila melanogaster)
SPZ dimer:TL dimer:SPZ dimer:MYD88:TUB:PLL [plasma membrane] (Drosophila melanogaster)
PLL [cytosol] (Drosophila melanogaster)
PLL kinase binds to TL:WEK:MYD88:TUB 'signalling complex' (Drosophila melanogaster)
PLL [cytosol] (Drosophila melanogaster)
SPZ dimer:TL dimer:SPZ dimer:PLL:MYD88:TUB:WEK dimer:MYD88:TUB:PLL [plasma membrane] (Drosophila melanogaster)
PLL [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q05652 pll
Gene Names
pll, CG5974
Chain
chain:1-501
Reference Genes
BioGPS Gene:43283 pll
KEGG Gene (Drosophila melanogaster):Dmel_CG5974 pll
Monarch:43283 pll
NCBI Gene:43283 pll
UCSC:Q05652 pll
Reference Transcript
RefSeq:NM_057623.4 pll
RefSeq:NM_001276079.1 pll
Other Identifiers
04150+2.7.11.1
04151+2.7.11.1
04714+2.7.11.1
04926+2.7.11.1
05163+2.7.11.1
05165+2.7.11.1
05170+2.7.11.1
142881_at
1638252_at
1D2Z
1IK7
1YGO
7227.FBpp0084549
A0A0B4KHQ0
AAF56686.1
AGB96388.1
AY069657
BT056264
EntrezGene:43283
FBgn0010441
FBpp0084549
FBpp0306780
FBtr0085179
FBtr0334732
GO:0000166
GO:0002376
GO:0002804
GO:0003674
GO:0004672
GO:0004674
GO:0005515
GO:0005524
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005737
GO:0005829
GO:0005886
GO:0006464
GO:0006468
GO:0006915
GO:0006950
GO:0006952
GO:0007165
GO:0007352
GO:0007526
GO:0008063
GO:0008150
GO:0008219
GO:0008283
GO:0009620
GO:0009790
GO:0009950
GO:0009953
GO:0016020
GO:0016301
GO:0016310
GO:0016740
GO:0019221
GO:0019732
GO:0019904
GO:0030097
GO:0030162
GO:0035172
GO:0035556
GO:0043167
GO:0043226
GO:0045087
GO:0046777
GO:0048262
GO:0048856
GO:0061760
IPR000488
IPR000719
IPR008271
IPR011009
IPR011029
IPR017441
IPR037924
L08476
NM_001276079.1
NM_057623.4
NP_001263008.1
NP_476971.1
PF00069
PF00531
SM00005
SM00220
UPI000012489F
Participant Of
hasComponent
SPZ dimer:TL dimer:SPZ dimer:MYD88:TUB:PLL [plasma membrane]
SPZ dimer:TL dimer:SPZ dimer:PLL:MYD88:TUB:WEK dimer:MYD88:TUB:Phospho PLL [plasma membrane]
SPZ dimer:TL dimer:SPZ dimer:PLL:MYD88:TUB:WEK dimer:MYD88:TUB:Phospho PLL:DL dimer:CACT [plasma membrane]
SPZ dimer:TL dimer:SPZ dimer:PLL:MYD88:TUB:WEK dimer:MYD88:TUB:Phospho PLL:Phospho DL dimer:Phospho CACT [plasma membrane]
SPZ dimer:TL dimer:SPZ dimer:PLL:MYD88:TUB:WEK dimer:MYD88:TUB:PLL [plasma membrane]
input
PLL kinase binds to TL:MYD88:TUB 'signalling complex'
PLL kinase binds to TL:WEK:MYD88:TUB 'signalling complex'
Other forms of this molecule
Phospho PLL [cytosol]
phospho-K63polyUb-hp-IRAK1 [endosome membrane]
phospho-K63polyUb-hp-IRAK1 [cytosol]
IRAK2 [endosome membrane]
IRAK1 [endosome membrane]
phospho-p-T209-IRAK1 [endosome membrane]
phospho-p-T209,T387-IRAK1 [endosome membrane]
phospho-p-IRAK2 [endosome membrane]
phospho-p-2S,S376,T,T209,T387-IRAK1 [endosome membrane]
IRAK2 [cytosol]
phospho-p-2S,S376,T,T209,T387-IRAK1 [plasma membrane]
phospho-p-IRAK2 [plasma membrane]
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol]
phospho-p-IRAK2 [cytosol]
IRAK1 [cytosol]
Cross References
RefSeq
NP_476971.1
,
NP_001263008.1
Flybase
FBgn0010441
PRO
Q05652
PDB
1IK7
,
1YGO
,
1D2Z
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P22812 tub
4
IRAK4 [endosome membrane]
(R-DME-975167)
TUB [cytosol]
(R-DME-206155)
phospho-p-T342,T345,S346-IRAK4 [endosome membrane]
(R-DME-975149)
IRAK4 [cytosol]
(R-DME-166081)
0.927
12
UniProt:P15330 dl
23
Phospho DL [cytosol]
(R-DME-214732)
DL [cytosol]
(R-DME-206011)
Phospho DL [nucleoplasm]
(R-DME-214731)
SUMO3-K37,K122,K123-RELA [nucleoplasm]
(R-DME-4755466)
MeK310-RELA [nucleoplasm]
(R-DME-8865233)
NFKB1(1-968) [secretory granule lumen]
(R-DME-6801004)
NFKB1(1-968) [extracellular region]
(R-DME-6806304)
NFKB1(1-968) [specific granule lumen]
(R-DME-6799557)
phospho-p-S276,5xAcK-RELA [nucleoplasm]
(R-DME-5660642)
NFKB1(1-968) [cytosol]
(R-DME-451607)
NFKB1(1-433) [cytosol]
(R-DME-168168)
RELA [cytosol]
(R-DME-168172)
NFKB1(1-433) [nucleoplasm]
(R-DME-177655)
RELA [nucleoplasm]
(R-DME-177676)
RELB [cytosol]
(R-DME-5607652)
phospho-K48-polyUb-p-7S-p100 [cytosol]
(R-DME-5607636)
NFKB2(1-454) [cytosol]
(R-DME-168144)
NFKB2(1-454) [nucleoplasm]
(R-DME-177674)
REL [cytosol]
(R-DME-1168579)
REL [nucleoplasm]
(R-DME-1168585)
phospho-p-S276-RELA [nucleoplasm]
(R-DME-5624468)
RELB [nucleoplasm]
(R-DME-5607656)
NFKB2(1-900) [cytosol]
(R-DME-2677931)
0.502
3
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