Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyze Data
Species Comparison
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site map
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyze Data
Species Comparison
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site map
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
Phospho PLL [cytosol]
Stable Identifier
R-DME-206109
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Drosophila signaling pathways (Drosophila melanogaster)
Toll pathway (Drosophila melanogaster)
Degradation of NF-kappa-B inhibitor, CACT (Drosophila melanogaster)
Activated PLL kinase is autophosphorylated in the TL receptor 'signalling complex' (Drosophila melanogaster)
Activated PLL kinase is autophosphorylated in TL:MYD88:TUB:PLL 'signalling complex' (Drosophila melanogaster)
SPZ dimer:TL dimer:SPZ dimer:MYD88:TUB:Phospho PLL [plasma membrane] (Drosophila melanogaster)
Phospho PLL [cytosol] (Drosophila melanogaster)
Activated PLL kinase is autophosphorylated in TL:WEK:MYD88:TUB:PLL 'signalling complex' (Drosophila melanogaster)
SPZ dimer:TL dimer:SPZ dimer:PLL:MYD88:TUB:WEK dimer:MYD88:TUB:Phospho PLL [plasma membrane] (Drosophila melanogaster)
Phospho PLL [cytosol] (Drosophila melanogaster)
DL and DIF homodimers bind to TUB and phosphorylated PLL in the TL receptor 'signalling complex' (Drosophila melanogaster)
DL dimer binds to TUB and phosphorylated PLL in TL:WEK:MYD88:TUB:PLL 'signalling complex' (Drosophila melanogaster)
SPZ dimer:TL dimer:SPZ dimer:PLL:MYD88:TUB:WEK dimer:MYD88:TUB:Phospho PLL [plasma membrane] (Drosophila melanogaster)
Phospho PLL [cytosol] (Drosophila melanogaster)
SPZ dimer:TL dimer:SPZ dimer:PLL:MYD88:TUB:WEK dimer:MYD88:TUB:Phospho PLL:DL dimer:CACT [plasma membrane] (Drosophila melanogaster)
Phospho PLL [cytosol] (Drosophila melanogaster)
DL/DIF dimer binds to TUB and phosphorylated PLL in TL:MYD88:TUB:PLL 'signalling complex' (Drosophila melanogaster)
SPZ dimer:TL dimer:SPZ dimer:MYD88:TUB:Phospho PLL [plasma membrane] (Drosophila melanogaster)
Phospho PLL [cytosol] (Drosophila melanogaster)
SPZ dimer:TL dimer:SPZ dimer:MYD88:TUB:Phospho PLL:DL/DIF dimer:CACT [plasma membrane] (Drosophila melanogaster)
Phospho PLL [cytosol] (Drosophila melanogaster)
DL and DIF homodimers complexed with CACT are all phosphorylated in the TL receptor 'signalling complex' (Drosophila melanogaster)
CACT and DL dimer are phosphorylated in TL:WEK:MYD88:TUB:PLL 'signalling complex' (Drosophila melanogaster)
SPZ dimer:TL dimer:SPZ dimer:PLL:MYD88:TUB:WEK dimer:MYD88:TUB:Phospho PLL:DL dimer:CACT [plasma membrane] (Drosophila melanogaster)
Phospho PLL [cytosol] (Drosophila melanogaster)
SPZ dimer:TL dimer:SPZ dimer:PLL:MYD88:TUB:WEK dimer:MYD88:TUB:Phospho PLL:Phospho DL dimer:Phospho CACT [plasma membrane] (Drosophila melanogaster)
Phospho PLL [cytosol] (Drosophila melanogaster)
CACT and DL/DIF dimer are phosphorylated in TL:MYD88:TUB:PLL 'signalling complex' (Drosophila melanogaster)
SPZ dimer:TL dimer:SPZ dimer:MYD88:TUB:Phospho PLL:DL/DIF dimer:CACT [plasma membrane] (Drosophila melanogaster)
Phospho PLL [cytosol] (Drosophila melanogaster)
SPZ dimer:TL dimer:SPZ dimer:MYD88:TUB:Phospho PLL:Phospho DL/DIF dimer:Phospho CACT [plasma membrane] (Drosophila melanogaster)
Phospho PLL [cytosol] (Drosophila melanogaster)
Phosphorylated CACT, DL and DIF homodimers dissociate from the TL receptor 'signalling complex' (Drosophila melanogaster)
Phosphorylated CACT and DL dimer dissociate from the TL:WEK:MYD88:TUB:PLL 'signalling complex' (Drosophila melanogaster)
SPZ dimer:TL dimer:SPZ dimer:PLL:MYD88:TUB:WEK dimer:MYD88:TUB:Phospho PLL [plasma membrane] (Drosophila melanogaster)
Phospho PLL [cytosol] (Drosophila melanogaster)
SPZ dimer:TL dimer:SPZ dimer:PLL:MYD88:TUB:WEK dimer:MYD88:TUB:Phospho PLL:Phospho DL dimer:Phospho CACT [plasma membrane] (Drosophila melanogaster)
Phospho PLL [cytosol] (Drosophila melanogaster)
Phosphorylated CACT and DL/DIF dimer dissociate from the TL:MYD88:TUB:PLL 'signalling complex' (Drosophila melanogaster)
SPZ dimer:TL dimer:SPZ dimer:MYD88:TUB:Phospho PLL [plasma membrane] (Drosophila melanogaster)
Phospho PLL [cytosol] (Drosophila melanogaster)
SPZ dimer:TL dimer:SPZ dimer:MYD88:TUB:Phospho PLL:Phospho DL/DIF dimer:Phospho CACT [plasma membrane] (Drosophila melanogaster)
Phospho PLL [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q05652 pll
Gene Names
pll, CG5974
Chain
chain:1-501
Reference Genes
BioGPS Gene:43283 pll
dbSNP Gene:43283 pll
KEGG Gene (Drosophila melanogaster):Dmel_CG5974 pll
Monarch:43283 pll
NCBI Gene:43283 pll
UCSC:Q05652 pll
Reference Transcript
RefSeq:NM_057623.4 pll
RefSeq:NM_001276079.1 pll
Other Identifiers
04150+2.7.11.1
04151+2.7.11.1
04714+2.7.11.1
04926+2.7.11.1
05163+2.7.11.1
05165+2.7.11.1
05170+2.7.11.1
142881_at
1638252_at
1D2Z
1IK7
1YGO
7227.FBpp0084549
A0A0B4KHQ0
AAF56686.1
AGB96388.1
AY069657
BT056264
EntrezGene:43283
FBgn0010441
FBpp0084549
FBpp0306780
FBtr0085179
FBtr0334732
GO:0000166
GO:0002376
GO:0002804
GO:0003674
GO:0004672
GO:0004674
GO:0005515
GO:0005524
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005737
GO:0005829
GO:0005886
GO:0006464
GO:0006468
GO:0006915
GO:0006950
GO:0006952
GO:0007165
GO:0007352
GO:0007526
GO:0008063
GO:0008150
GO:0008219
GO:0008283
GO:0009620
GO:0009790
GO:0009950
GO:0009953
GO:0016020
GO:0016301
GO:0016310
GO:0016740
GO:0019732
GO:0019904
GO:0030097
GO:0030162
GO:0035172
GO:0035556
GO:0043167
GO:0043226
GO:0045087
GO:0046777
GO:0048262
GO:0048856
GO:0061760
IPR000488
IPR000719
IPR008271
IPR011009
IPR011029
IPR017441
IPR037924
L08476
NM_001276079.1
NM_057623.4
NP_001263008.1
NP_476971.1
PF00069
PF00531
SM00005
SM00220
UPI000012489F
Participant Of
hasComponent
SPZ dimer:TL dimer:SPZ dimer:MYD88:TUB:Phospho PLL [plasma membrane]
SPZ dimer:TL dimer:SPZ dimer:MYD88:TUB:Phospho PLL:DL/DIF dimer:CACT [plasma membrane]
SPZ dimer:TL dimer:SPZ dimer:MYD88:TUB:Phospho PLL:Phospho DL/DIF dimer:Phospho CACT [plasma membrane]
SPZ dimer:TL dimer:SPZ dimer:PLL:MYD88:TUB:WEK dimer:MYD88:TUB:Phospho PLL [plasma membrane]
SPZ dimer:TL dimer:SPZ dimer:PLL:MYD88:TUB:WEK dimer:MYD88:TUB:Phospho PLL:DL dimer:CACT [plasma membrane]
SPZ dimer:TL dimer:SPZ dimer:PLL:MYD88:TUB:WEK dimer:MYD88:TUB:Phospho PLL:Phospho DL dimer:Phospho CACT [plasma membrane]
Other forms of this molecule
PLL [cytosol]
phospho-K63polyUb-hp-IRAK1 [endosome membrane]
phospho-K63polyUb-hp-IRAK1 [cytosol]
IRAK2 [endosome membrane]
IRAK1 [endosome membrane]
phospho-p-T209-IRAK1 [endosome membrane]
phospho-p-T209,T387-IRAK1 [endosome membrane]
phospho-p-2S,S376,T,T209,T387-IRAK1 [endosome membrane]
phospho-p-IRAK2 [endosome membrane]
IRAK2 [cytosol]
phospho-p-2S,S376,T,T209,T387-IRAK1 [plasma membrane]
phospho-p-IRAK2 [plasma membrane]
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol]
phospho-p-IRAK2 [cytosol]
IRAK1 [cytosol]
Modified Residues
Name
phosphorylated residue at unknown position
PsiMod Name
phosphorylated residue [MOD:00696]
PsiMod Definition
A protein modification that effectively replaces a hydrogen atom with a phosphate group.
Cross References
RefSeq
NP_476971.1
,
NP_001263008.1
Flybase
FBgn0010441
IntEnz
2.7.11.1
PRO
Q05652
PDB
1D2Z
,
1IK7
,
1YGO
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P22812 tub
4
IRAK4 [endosome membrane]
(R-DME-975167)
TUB [cytosol]
(R-DME-206155)
phospho-p-T342,T345,S346-IRAK4 [endosome membrane]
(R-DME-975149)
IRAK4 [cytosol]
(R-DME-166081)
0.927
12
UniProt:P15330 dl
23
Phospho DL [cytosol]
(R-DME-214732)
DL [cytosol]
(R-DME-206011)
Phospho DL [nucleoplasm]
(R-DME-214731)
SUMO3-K37,K122,K123-RELA [nucleoplasm]
(R-DME-4755466)
MeK310-RELA [nucleoplasm]
(R-DME-8865233)
phospho-p-S276,5xAcK-RELA [nucleoplasm]
(R-DME-5660642)
NFKB1(1-968) [cytosol]
(R-DME-451607)
NFKB2(1-454) [cytosol]
(R-DME-168144)
NFKB1(1-433) [cytosol]
(R-DME-168168)
RELA [cytosol]
(R-DME-168172)
NFKB1(1-433) [nucleoplasm]
(R-DME-177655)
NFKB2(1-454) [nucleoplasm]
(R-DME-177674)
RELA [nucleoplasm]
(R-DME-177676)
REL [cytosol]
(R-DME-1168579)
REL [nucleoplasm]
(R-DME-1168585)
RELB [cytosol]
(R-DME-5607652)
phospho-K48-polyUb-p-7S-p100 [cytosol]
(R-DME-5607636)
NFKB1(1-968) [specific granule lumen]
(R-DME-6799557)
NFKB1(1-968) [extracellular region]
(R-DME-6806304)
NFKB1(1-968) [secretory granule lumen]
(R-DME-6801004)
phospho-p-S276-RELA [nucleoplasm]
(R-DME-5624468)
RELB [nucleoplasm]
(R-DME-5607656)
NFKB2(1-900) [cytosol]
(R-DME-2677931)
0.502
3
© 2019
Reactome
