Phosphorylation of ARM by CKIalpha

Stable Identifier
R-DME-209134
Type
Reaction [transition]
Species
Drosophila melanogaster
Compartment
cytosol
ReviewStatus
5/5
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Phosphorylation of ARM by CKIalpha
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Armadillo (ARM) is primed for phosphorylation by CKIalpha at Ser56.
Literature References
PubMed ID Title Journal Year
12000790 Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathway

Andersen, JS, Birman, Y, Mann, M, Ben-Shushan, E, Alkalay, I, Hatzubai, A, Amit, S, Ben-Neriah, Y

Genes Dev 2002
14966281 Biochemical characterization of the Drosophila wingless signaling pathway based on RNA interference

Shirakawa, T, Sese, S, Iwatsubo, T, Yanagawa, S, Lee, JS, Tomita, T, Matsubayashi, H

Mol Cell Biol 2004
11955436 Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism

Zhang, Z, Baeg, GH, Lin, X, Tan, Y, Li, Y, He, X, Semenov, M, Han, C, Liu, C

Cell 2002
11927557 Casein kinase I phosphorylates the Armadillo protein and induces its degradation in Drosophila

Kadowaki, T, Sese, S, Yanagawa, S, Lee, JS, Matsubayashi, H, Matsuda, Y, Ishimoto, A

EMBO J 2002
Participants
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as an event of
Catalyst Activity

protein serine/threonine kinase activity of ARM:Phospho (3 sites) AXN:Phospho (6 sites) APC:PP2A:CKIalpha:DCO:SGG [cytosol]

Physical Entity
ARM:Phospho (3 sites) AXN:Phospho (6 sites) APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
Activity
protein serine/threonine kinase activity (GO:0004674)
Authored
Williams, MG  (2006-07-26)
Reviewed
Nusse, R  (2008-01-19)
Created
Williams, MG  (2006-06-28)
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