Activated HOP is autophosphorylated and/or transphosphorylated

Stable Identifier
R-DME-209336
Type
Reaction [transition]
Species
Drosophila melanogaster
Compartment
ReviewStatus
5/5
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The activated HOPs phosphorylate themselves and each other. The precise residue position where this takes place is currently unknown as there are many potential phosphorylation sites on HOP.
Literature References
PubMed ID Title Journal Year
9784499 Drosophila unpaired encodes a secreted protein that activates the JAK signaling pathway

Gilman, M, Harrison, DA, McCoon, PE, Perrimon, N, Binari, R

Genes Dev 1998
11825879 mom identifies a receptor for the Drosophila JAK/STAT signal transduction pathway and encodes a protein distantly related to the mammalian cytokine receptor family

Chen, HW, Chen, X, Marinissen, MJ, Gutkind, JS, Oh, SW, Hou, SX

Genes Dev 2002
Participants
Participates
Catalyst Activity

protein tyrosine kinase activity of HOP:DOME:UPD:DOME:HOP [plasma membrane]

Authored
Reviewed
Created
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