SPN27A binds to and inhibits EA protease activity

Stable Identifier
R-DME-209376
Type
Reaction [binding]
Species
Drosophila melanogaster
Compartment
extracellular region
ReviewStatus
5/5
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SPN27A binds to and inhibits EA protease activity
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In dorsoventral patterning, the serpin SPN27A binds to Easter (EA) serine protease. This complex inhibits Spatzle (SPZ) dimer processing.
Literature References
PubMed ID Title Journal Year
14667416 Spatial regulation of developmental signaling by a serpin

Hashimoto, C, Weiss, LA, Miller, JW, Morisato, D, Kim, DR

Dev Cell 2003
Participants
Input
Output
Participates
as an event of
Authored
Williams, MG  (2007-07-11)
Reviewed
Lemaitre, B  (2008-06-20)
Silverman, N  (2008-06-20)
Created
Williams, MG  (2007-07-12)
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