Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
Ubiquitination and degradation of phosphorylated ARM
Stable Identifier
R-DME-209461
Type
Pathway
Species
Drosophila melanogaster
Compartment
cytosol
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
Drosophila signaling pathways (Drosophila melanogaster)
Wingless pathway (Drosophila melanogaster)
WG ligand not bound to FZ receptors (Drosophila melanogaster)
Ubiquitination and degradation of phosphorylated ARM (Drosophila melanogaster)
General
SBML
|
BioPAX
Level 2
Level 3
|
PDF
SVG
|
PNG
Low
Medium
High
|
PPTX
|
SBGN
Click the image above or
here
to open this pathway in the Pathway Browser
Spatzle (SPZ) dimer binding leads to Toll (TL) receptor homodimerisation and activation.
Literature References
PubMed ID
Title
Journal
Year
15041171
Rethinking WNT signaling
Tolwinski, NS
,
Wieschaus, E
Trends Genet
2004
16520547
Regulation of Wnt signaling by protein-protein interaction and post-translational modifications
Kikuchi, A
,
Yamamoto, H
,
Kishida, S
Exp Mol Med
2006
15473860
The Wnt signaling pathway in development and disease
Logan, CY
,
Nusse, R
Annu Rev Cell Dev Biol
2004
Participants
Events
SLMB binds to phosphorylated ARM to form the 'destruction complex'
(Drosophila melanogaster)
Dissociation of free ubiquitinated and phosphorylated ARM from SLMB and the 'destruction complex'
(Drosophila melanogaster)
Ubiquitinated and phosphorylated ARM binds to and is degraded by the proteasome complex
(Drosophila melanogaster)
Participates
as an event of
WG ligand not bound to FZ receptors (Drosophila melanogaster)
Authored
Williams, MG (2006-07-26)
Reviewed
Nusse, R (2008-01-19)
Created
Williams, MG (2006-06-28)
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text