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WG ligand bound to FZ receptors
Stable Identifier
R-DME-209469
Type
Pathway
Species
Drosophila melanogaster
ReviewStatus
5/5
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Drosophila signaling pathways (Drosophila melanogaster)
Wingless pathway (Drosophila melanogaster)
WG ligand bound to FZ receptors (Drosophila melanogaster)
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Spatzle (SPZ) dimer binding leads to Toll (TL) receptor homodimerisation and activation.
Literature References
PubMed ID
Title
Journal
Year
15041171
Rethinking WNT signaling
Tolwinski, NS
,
Wieschaus, E
Trends Genet
2004
16520547
Regulation of Wnt signaling by protein-protein interaction and post-translational modifications
Kikuchi, A
,
Yamamoto, H
,
Kishida, S
Exp Mol Med
2006
15473860
The Wnt signaling pathway in development and disease
Logan, CY
,
Nusse, R
Annu Rev Cell Dev Biol
2004
Participants
Events
Assembly of receptor complex
(Drosophila melanogaster)
Recruitment of the 'destruction complex' to the receptor complex, the degradation of AXN and release of ARM
(Drosophila melanogaster)
Transport of ARM to the nucleus
(Drosophila melanogaster)
Transcription activation by ARM
(Drosophila melanogaster)
Participates
as an event of
Wingless pathway (Drosophila melanogaster)
Authored
Williams, MG (2006-07-26)
Reviewed
Nusse, R (2008-01-19)
Created
Williams, MG (2006-06-28)
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