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ROCK1 [cytosol]
Stable Identifier
R-DME-212509
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
Q9VXE3
Locations in the PathwayBrowser
Expand all
Developmental Biology (Drosophila melanogaster)
Nervous system development (Drosophila melanogaster)
Axon guidance (Drosophila melanogaster)
EPH-Ephrin signaling (Drosophila melanogaster)
EPHB-mediated forward signaling (Drosophila melanogaster)
RHOA:GTP binds ROCK, activating it (Drosophila melanogaster)
RHOA:GTP:ROCK1,ROCK2 [plasma membrane] (Drosophila melanogaster)
ROCK1,ROCK2 [cytosol] (Drosophila melanogaster)
ROCK1 [cytosol] (Drosophila melanogaster)
ROCK1,ROCK2 [cytosol] (Drosophila melanogaster)
ROCK1 [cytosol] (Drosophila melanogaster)
Semaphorin interactions (Drosophila melanogaster)
Sema4D in semaphorin signaling (Drosophila melanogaster)
Sema4D induced cell migration and growth-cone collapse (Drosophila melanogaster)
ROCK activation by RHO (Drosophila melanogaster)
Activated ROCK:RhoA/B/C:GTP [plasma membrane] (Drosophila melanogaster)
ROCK1,ROCK2 [cytosol] (Drosophila melanogaster)
ROCK1 [cytosol] (Drosophila melanogaster)
ROCK1,ROCK2 [cytosol] (Drosophila melanogaster)
ROCK1 [cytosol] (Drosophila melanogaster)
ROCK1,ROCK2:ROCKi [cytosol] (Drosophila melanogaster)
ROCK1,ROCK2 [cytosol] (Drosophila melanogaster)
ROCK1 [cytosol] (Drosophila melanogaster)
ROCK1,2 bind ROCKi (Drosophila melanogaster)
ROCK1,ROCK2 [cytosol] (Drosophila melanogaster)
ROCK1 [cytosol] (Drosophila melanogaster)
ROCK1,ROCK2:ROCKi [cytosol] (Drosophila melanogaster)
ROCK1,ROCK2 [cytosol] (Drosophila melanogaster)
ROCK1 [cytosol] (Drosophila melanogaster)
Programmed Cell Death (Drosophila melanogaster)
Apoptosis (Drosophila melanogaster)
Apoptotic execution phase (Drosophila melanogaster)
Apoptotic cleavage of cellular proteins (Drosophila melanogaster)
Caspase-mediated cleavage of Rock-1 (Drosophila melanogaster)
ROCK1 [cytosol] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Signaling by GPCR (Drosophila melanogaster)
GPCR downstream signalling (Drosophila melanogaster)
G alpha (12/13) signalling events (Drosophila melanogaster)
ROCK activation by RHO (Drosophila melanogaster)
Activated ROCK:RhoA/B/C:GTP [plasma membrane] (Drosophila melanogaster)
ROCK1,ROCK2 [cytosol] (Drosophila melanogaster)
ROCK1 [cytosol] (Drosophila melanogaster)
ROCK1,ROCK2 [cytosol] (Drosophila melanogaster)
ROCK1 [cytosol] (Drosophila melanogaster)
ROCK1,ROCK2:ROCKi [cytosol] (Drosophila melanogaster)
ROCK1,ROCK2 [cytosol] (Drosophila melanogaster)
ROCK1 [cytosol] (Drosophila melanogaster)
ROCK1,2 bind ROCKi (Drosophila melanogaster)
ROCK1,ROCK2 [cytosol] (Drosophila melanogaster)
ROCK1 [cytosol] (Drosophila melanogaster)
ROCK1,ROCK2:ROCKi [cytosol] (Drosophila melanogaster)
ROCK1,ROCK2 [cytosol] (Drosophila melanogaster)
ROCK1 [cytosol] (Drosophila melanogaster)
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by VEGF (Drosophila melanogaster)
VEGFA-VEGFR2 Pathway (Drosophila melanogaster)
RHOA:GTP:Mg2+ binds ROCK1,ROCK2 (Drosophila melanogaster)
RHOA:GTP:ROCK1,ROCK2 [plasma membrane] (Drosophila melanogaster)
ROCK1,ROCK2 [cytosol] (Drosophila melanogaster)
ROCK1 [cytosol] (Drosophila melanogaster)
ROCK1,ROCK2 [cytosol] (Drosophila melanogaster)
ROCK1 [cytosol] (Drosophila melanogaster)
ROCK1,ROCK2 are activated (Drosophila melanogaster)
RHOA:GTP:Mg2+:Activated ROCK1,ROCK2 [cytosol] (Drosophila melanogaster)
ROCK1,ROCK2 [cytosol] (Drosophila melanogaster)
ROCK1 [cytosol] (Drosophila melanogaster)
RHOA:GTP:ROCK1,ROCK2 [plasma membrane] (Drosophila melanogaster)
ROCK1,ROCK2 [cytosol] (Drosophila melanogaster)
ROCK1 [cytosol] (Drosophila melanogaster)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Drosophila melanogaster)
Signaling by Rho GTPases (Drosophila melanogaster)
RHO GTPase Effectors (Drosophila melanogaster)
RHO GTPases Activate ROCKs (Drosophila melanogaster)
ROCK activation by RHO (Drosophila melanogaster)
Activated ROCK:RhoA/B/C:GTP [plasma membrane] (Drosophila melanogaster)
ROCK1,ROCK2 [cytosol] (Drosophila melanogaster)
ROCK1 [cytosol] (Drosophila melanogaster)
ROCK1,ROCK2 [cytosol] (Drosophila melanogaster)
ROCK1 [cytosol] (Drosophila melanogaster)
ROCK1,ROCK2:ROCKi [cytosol] (Drosophila melanogaster)
ROCK1,ROCK2 [cytosol] (Drosophila melanogaster)
ROCK1 [cytosol] (Drosophila melanogaster)
ROCK1,2 bind ROCKi (Drosophila melanogaster)
ROCK1,ROCK2 [cytosol] (Drosophila melanogaster)
ROCK1 [cytosol] (Drosophila melanogaster)
ROCK1,ROCK2:ROCKi [cytosol] (Drosophila melanogaster)
ROCK1,ROCK2 [cytosol] (Drosophila melanogaster)
ROCK1 [cytosol] (Drosophila melanogaster)
RHO GTPase cycle (Drosophila melanogaster)
RHOA GTPase cycle (Drosophila melanogaster)
RHOA binds effectors at the plasma membrane (Drosophila melanogaster)
RHOA plasma membrane effectors [cytosol] (Drosophila melanogaster)
ROCK1 [cytosol] (Drosophila melanogaster)
RHOA:GTP:cytosolic RHOA effectors [plasma membrane] (Drosophila melanogaster)
RHOA plasma membrane effectors [cytosol] (Drosophila melanogaster)
ROCK1 [cytosol] (Drosophila melanogaster)
RHOB GTPase cycle (Drosophila melanogaster)
RHOB binds effectors at the plasma membrane (Drosophila melanogaster)
RHOB effectors (plasma membrane) [cytosol] (Drosophila melanogaster)
ROCK1 [cytosol] (Drosophila melanogaster)
RHOB:GTP:cytosolic RHOB effectors [plasma membrane] (Drosophila melanogaster)
RHOB effectors (plasma membrane) [cytosol] (Drosophila melanogaster)
ROCK1 [cytosol] (Drosophila melanogaster)
RHOBTB GTPase Cycle (Drosophila melanogaster)
RHOBTB1 GTPase cycle (Drosophila melanogaster)
RHOBTB1 binds interacting proteins at the endosome membrane (Drosophila melanogaster)
RHOBTB1 interacting proteins [cytosol] (Drosophila melanogaster)
ROCK1 [cytosol] (Drosophila melanogaster)
RHOBTB1:GTP:RHOBTB1 interacting proteins [endosome membrane] (Drosophila melanogaster)
RHOBTB1 interacting proteins [cytosol] (Drosophila melanogaster)
ROCK1 [cytosol] (Drosophila melanogaster)
RHOH GTPase cycle (Drosophila melanogaster)
RHOH binds effectors at the plasma membrane (Drosophila melanogaster)
RHOH effectors [cytosol] (Drosophila melanogaster)
ROCK1 [cytosol] (Drosophila melanogaster)
RHOH:GTP:RHOH effectors [plasma membrane] (Drosophila melanogaster)
RHOH effectors [cytosol] (Drosophila melanogaster)
ROCK1 [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9VXE3
Reference Genes
BioGPS Gene:43916
ENSEMBL:FBgn0026181
Flybase:FBgn0026181
Monarch:43916
NCBI Gene:43916
UCSC:Q9VXE3
Reference Transcript
RefSeq:NM_080535.3
Other Identifiers
153832_at
1626306_at
43916
GO:0000022
GO:0000166
GO:0000278
GO:0000281
GO:0000910
GO:0001736
GO:0001737
GO:0001932
GO:0003383
GO:0003384
GO:0003824
GO:0004672
GO:0004674
GO:0005515
GO:0005524
GO:0005737
GO:0005829
GO:0005856
GO:0005886
GO:0005911
GO:0005938
GO:0006468
GO:0007010
GO:0007059
GO:0007163
GO:0007266
GO:0007300
GO:0007302
GO:0007309
GO:0007391
GO:0008335
GO:0008360
GO:0008544
GO:0015629
GO:0016301
GO:0016310
GO:0016331
GO:0016740
GO:0018107
GO:0022414
GO:0023052
GO:0030036
GO:0030154
GO:0030866
GO:0031032
GO:0031267
GO:0031532
GO:0032065
GO:0032231
GO:0032956
GO:0034330
GO:0035191
GO:0035317
GO:0036211
GO:0042060
GO:0042067
GO:0042325
GO:0043226
GO:0044291
GO:0045179
GO:0045184
GO:0046872
GO:0048598
GO:0048599
GO:0048856
GO:0050770
GO:0051020
GO:0051496
GO:0072518
GO:0090303
GO:0090527
GO:0106036
GO:0106037
GO:0106310
GO:0140014
GO:0140096
GO:1901648
GO:1901739
GO:1901888
GO:1902408
GO:1903035
Participates
as a member of
RHOA plasma membrane effectors [cytosol] (Drosophila melanogaster)
RHOBTB1 interacting proteins [cytosol] (Drosophila melanogaster)
RHOB effectors (plasma membrane) [cytosol] (Drosophila melanogaster)
ROCK1,ROCK2 [cytosol] (Drosophila melanogaster)
as a candidate of
RHOH effectors [cytosol] (Drosophila melanogaster)
as an input of
Caspase-mediated cleavage of Rock-1 (Drosophila melanogaster)
Other forms of this molecule
ROCK1 [extracellular region]
ROCK1 [secretory granule lumen]
ROCK2 [cytosol]
ROCK1(1114-1354) [cytosol]
ROCK1(1-1113) [cytosol]
Inferred From
Activated ROCK1 [cytosol]
(Homo sapiens)
ROCK1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_536796.2
Flybase
FBgn0026181
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