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GSK3B [cytosol]
Stable Identifier
R-DME-2997551-2
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
P83101
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Drosophila melanogaster)
Cellular responses to stress (Drosophila melanogaster)
Cellular response to heat stress (Drosophila melanogaster)
Regulation of HSF1-mediated heat shock response (Drosophila melanogaster)
Constitutive phosphorylation by GSK3 (Drosophila melanogaster)
Homologues of GSK3B [cytosol] (Drosophila melanogaster)
GSK3B [cytosol] (Drosophila melanogaster)
Developmental Biology (Drosophila melanogaster)
Nervous system development (Drosophila melanogaster)
Axon guidance (Drosophila melanogaster)
Semaphorin interactions (Drosophila melanogaster)
CRMPs in Sema3A signaling (Drosophila melanogaster)
Phosphorylation of CRMPs by GSK3beta (Drosophila melanogaster)
Homologues of GSK3B [cytosol] (Drosophila melanogaster)
GSK3B [cytosol] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Signaling by Hedgehog (Drosophila melanogaster)
Hedgehog 'off' state (Drosophila melanogaster)
GLI3 is processed to GLI3R by the proteasome (Drosophila melanogaster)
GSK3 phosphorylates p-GLI3 (Drosophila melanogaster)
Homologues of GSK3B [cytosol] (Drosophila melanogaster)
GSK3B [cytosol] (Drosophila melanogaster)
Signaling by WNT (Drosophila melanogaster)
Degradation of beta-catenin by the destruction complex (Drosophila melanogaster)
AXIN is phosphorylated in the destruction complex (Drosophila melanogaster)
AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
Homologues of GSK3B [cytosol] (Drosophila melanogaster)
GSK3B [cytosol] (Drosophila melanogaster)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
Homologues of GSK3B [cytosol] (Drosophila melanogaster)
GSK3B [cytosol] (Drosophila melanogaster)
Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex (Drosophila melanogaster)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Drosophila melanogaster)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
Homologues of GSK3B [cytosol] (Drosophila melanogaster)
GSK3B [cytosol] (Drosophila melanogaster)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
Homologues of GSK3B [cytosol] (Drosophila melanogaster)
GSK3B [cytosol] (Drosophila melanogaster)
Association of beta-catenin with the destruction complex (Drosophila melanogaster)
CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
Homologues of GSK3B [cytosol] (Drosophila melanogaster)
GSK3B [cytosol] (Drosophila melanogaster)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
Homologues of GSK3B [cytosol] (Drosophila melanogaster)
GSK3B [cytosol] (Drosophila melanogaster)
Beta-catenin phosphorylation cascade (Drosophila melanogaster)
Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Drosophila melanogaster)
CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
Homologues of GSK3B [cytosol] (Drosophila melanogaster)
GSK3B [cytosol] (Drosophila melanogaster)
p-S45 CTNNB1:p-Axin:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
Homologues of GSK3B [cytosol] (Drosophila melanogaster)
GSK3B [cytosol] (Drosophila melanogaster)
Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 (Drosophila melanogaster)
Homologues of GSK3B [cytosol] (Drosophila melanogaster)
GSK3B [cytosol] (Drosophila melanogaster)
p-S37,T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
Homologues of GSK3B [cytosol] (Drosophila melanogaster)
GSK3B [cytosol] (Drosophila melanogaster)
p-T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
Homologues of GSK3B [cytosol] (Drosophila melanogaster)
GSK3B [cytosol] (Drosophila melanogaster)
Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Drosophila melanogaster)
Homologues of GSK3B [cytosol] (Drosophila melanogaster)
GSK3B [cytosol] (Drosophila melanogaster)
p-S45 CTNNB1:p-Axin:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
Homologues of GSK3B [cytosol] (Drosophila melanogaster)
GSK3B [cytosol] (Drosophila melanogaster)
p-T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
Homologues of GSK3B [cytosol] (Drosophila melanogaster)
GSK3B [cytosol] (Drosophila melanogaster)
Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 (Drosophila melanogaster)
Homologues of GSK3B [cytosol] (Drosophila melanogaster)
GSK3B [cytosol] (Drosophila melanogaster)
p-S33,S37,T41,S45-beta-catenin:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
Homologues of GSK3B [cytosol] (Drosophila melanogaster)
GSK3B [cytosol] (Drosophila melanogaster)
p-S37,T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
Homologues of GSK3B [cytosol] (Drosophila melanogaster)
GSK3B [cytosol] (Drosophila melanogaster)
Degradation of ubiquitinated beta catenin by the proteasome (Drosophila melanogaster)
p-AXIN:CK1alpha:GSK3B:phospho-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
Homologues of GSK3B [cytosol] (Drosophila melanogaster)
GSK3B [cytosol] (Drosophila melanogaster)
ubiquitinated phospho-beta-catenin:RBX1:SCF(beta-TrCP1) complex [cytosol] (Drosophila melanogaster)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Drosophila melanogaster)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
Homologues of GSK3B [cytosol] (Drosophila melanogaster)
GSK3B [cytosol] (Drosophila melanogaster)
Dissociation of beta-catenin from Axin and association of beta catenin with phospho-(20 aa) APC in the detruction complex (Drosophila melanogaster)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
Homologues of GSK3B [cytosol] (Drosophila melanogaster)
GSK3B [cytosol] (Drosophila melanogaster)
Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) (Drosophila melanogaster)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Drosophila melanogaster)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
Homologues of GSK3B [cytosol] (Drosophila melanogaster)
GSK3B [cytosol] (Drosophila melanogaster)
ubiquitinated phospho-beta-catenin:RBX1:SCF(beta-TrCP1) complex [cytosol] (Drosophila melanogaster)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Drosophila melanogaster)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
Homologues of GSK3B [cytosol] (Drosophila melanogaster)
GSK3B [cytosol] (Drosophila melanogaster)
Phosphorylation of APC component of the destruction complex (Drosophila melanogaster)
CK1alpha (GSK3) [cytosol] (Drosophila melanogaster)
Homologues of GSK3B [cytosol] (Drosophila melanogaster)
GSK3B [cytosol] (Drosophila melanogaster)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
Homologues of GSK3B [cytosol] (Drosophila melanogaster)
GSK3B [cytosol] (Drosophila melanogaster)
p-S33,S37,T41,S45-beta-catenin:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
Homologues of GSK3B [cytosol] (Drosophila melanogaster)
GSK3B [cytosol] (Drosophila melanogaster)
TCF dependent signaling in response to WNT (Drosophila melanogaster)
Disassembly of the destruction complex and recruitment of AXIN to the membrane (Drosophila melanogaster)
DVL recruits GSK3beta:AXIN1 to the receptor complex (Drosophila melanogaster)
GSK3B:AXIN1 [cytosol] (Drosophila melanogaster)
Homologues of GSK3B [cytosol] (Drosophila melanogaster)
GSK3B [cytosol] (Drosophila melanogaster)
WNT:FZD:LRP5/6:DVL:AXIN:GSK3B [plasma membrane] (Drosophila melanogaster)
GSK3B:AXIN1 [cytosol] (Drosophila melanogaster)
Homologues of GSK3B [cytosol] (Drosophila melanogaster)
GSK3B [cytosol] (Drosophila melanogaster)
Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta (Drosophila melanogaster)
Homologues of GSK3B [cytosol] (Drosophila melanogaster)
GSK3B [cytosol] (Drosophila melanogaster)
WNT:FZD:LRP5/6:DVL:AXIN:GSK3B [plasma membrane] (Drosophila melanogaster)
GSK3B:AXIN1 [cytosol] (Drosophila melanogaster)
Homologues of GSK3B [cytosol] (Drosophila melanogaster)
GSK3B [cytosol] (Drosophila melanogaster)
WNT:FZD:p5S/T-LRP5/6:DVL:AXIN:GSK3B [plasma membrane] (Drosophila melanogaster)
GSK3B:AXIN1 [cytosol] (Drosophila melanogaster)
Homologues of GSK3B [cytosol] (Drosophila melanogaster)
GSK3B [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:P83101
Reference Genes
BioGPS Gene:318552
ENSEMBL:FBgn0046332
Flybase:FBgn0046332
KEGG Gene (Drosophila melanogaster):Dmel_CG31003
Monarch:318552
NCBI Gene:318552
UCSC:P83101
Reference Transcript
RefSeq:NM_170547.3
Other Identifiers
1632217_at
318552
GO:0000166
GO:0003824
GO:0004672
GO:0004674
GO:0005524
GO:0005737
GO:0006468
GO:0016301
GO:0016310
GO:0016740
GO:0022414
GO:0036211
GO:0048232
GO:0050321
GO:0140096
Participates
as a member of
Homologues of GSK3B [cytosol] (Drosophila melanogaster)
Other forms of this molecule
GSK3B [nucleoplasm]
Inferred From
GSK3B [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_733426.1
Flybase
FBgn0046332
IntEnz
2.7.11.26
PRO
P83101
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