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Go!
Dad [cytosol]
Stable Identifier
R-DME-3006350
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
SMAD6, A0A6H2EEY2
Locations in the PathwayBrowser
Expand all
Signal Transduction (Drosophila melanogaster)
Signaling by TGFB family members (Drosophila melanogaster)
Signaling by BMP (Drosophila melanogaster)
I-Smad binds to type I receptor, preventing Smad1/5/8 from being activated (Drosophila melanogaster)
BMP:p-BMPR:I-SMAD:SMURF [plasma membrane] (Drosophila melanogaster)
I-SMAD:SMURF [cytosol] (Drosophila melanogaster)
Dad [cytosol] (Drosophila melanogaster)
I-SMAD:SMURF [cytosol] (Drosophila melanogaster)
Dad [cytosol] (Drosophila melanogaster)
I-Smad competes with Co-Smad for R-Smad1/5/8 (Drosophila melanogaster)
Dad [cytosol] (Drosophila melanogaster)
I-SMAD:p-2S-SMAD1/5/8 [cytosol] (Drosophila melanogaster)
Dad [cytosol] (Drosophila melanogaster)
I-Smad competes with R-Smad1/5/8 for type I receptor (Drosophila melanogaster)
BMP2:BMP type II receptor:Phospho-BMP type I receptor:I-SMAD [plasma membrane] (Drosophila melanogaster)
Dad [cytosol] (Drosophila melanogaster)
Dad [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:A0A6H2EEY2
Gene Names
Dad
Reference Genes
ENSEMBL:FBgn0020493
FlyBase:FBgn0020493
UCSC:A0A6H2EEY2 Dad
Other Identifiers
152910_at
1633556_s_at
42059
GO:0003677
GO:0005515
GO:0005634
GO:0005667
GO:0005737
GO:0005829
GO:0006355
GO:0006357
GO:0007443
GO:0007448
GO:0007476
GO:0007488
GO:0009653
GO:0009791
GO:0010991
GO:0016335
GO:0016477
GO:0030154
GO:0030509
GO:0030514
GO:0030718
GO:0031290
GO:0035214
GO:0043226
GO:0045886
GO:0046872
GO:0048635
GO:0048856
GO:0048870
GO:0050793
GO:0051239
GO:0060392
GO:0060394
GO:0060395
GO:0070411
GO:0070700
GO:0071144
GO:0090254
GO:0098772
GO:0140416
Participates
as a component of
I-SMAD:SMURF [cytosol] (Drosophila melanogaster)
I-SMAD:p-2S-SMAD1/5/8 [cytosol] (Drosophila melanogaster)
BMP2:BMP type II receptor:Phospho-BMP type I receptor:I-SMAD [plasma membrane] (Drosophila melanogaster)
as an input of
I-Smad competes with Co-Smad for R-Smad1/5/8 (Drosophila melanogaster)
I-Smad competes with R-Smad1/5/8 for type I receptor (Drosophila melanogaster)
Other forms of this molecule
Dad [cytosol]
Dad [nucleoplasm]
Inferred From
I-SMAD [cytosol]
(Homo sapiens)
SMAD6 [cytosol]
(Homo sapiens)
Cross References
ENSEMBL
FBtr0479820
,
FBpp0428153
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q8I7C3-2 LASP
0.488
2
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