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trio [cytosol]
Stable Identifier
R-DME-3006505
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
KALRN, Q7KVD1
Locations in the PathwayBrowser
Expand all
Developmental Biology (Drosophila melanogaster)
Nervous system development (Drosophila melanogaster)
Axon guidance (Drosophila melanogaster)
EPH-Ephrin signaling (Drosophila melanogaster)
EPHB-mediated forward signaling (Drosophila melanogaster)
EPHB2 binds KALRN (Drosophila melanogaster)
EFNBs:p-EPHBs:KALRN [plasma membrane] (Drosophila melanogaster)
trio [cytosol] (Drosophila melanogaster)
trio [cytosol] (Drosophila melanogaster)
KALRN exchanges GTP for GDP on RAC1, activating it (Drosophila melanogaster)
EFNBs:p-EPHBs:KALRN [plasma membrane] (Drosophila melanogaster)
trio [cytosol] (Drosophila melanogaster)
trio [cytosol] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Death Receptor Signaling (Drosophila melanogaster)
p75 NTR receptor-mediated signalling (Drosophila melanogaster)
Cell death signalling via NRAGE, NRIF and NADE (Drosophila melanogaster)
NRAGE signals death through JNK (Drosophila melanogaster)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Drosophila melanogaster)
GEFs [cytosol] (Drosophila melanogaster)
trio [cytosol] (Drosophila melanogaster)
Signaling by GPCR (Drosophila melanogaster)
GPCR downstream signalling (Drosophila melanogaster)
G alpha (12/13) signalling events (Drosophila melanogaster)
GEFs activate RhoA,B,C (Drosophila melanogaster)
GEFs [cytosol] (Drosophila melanogaster)
trio [cytosol] (Drosophila melanogaster)
G alpha (q) signalling events (Drosophila melanogaster)
G alpha (q) binds to Trio family RhoGEFs (Drosophila melanogaster)
G-protein alpha (q/11):Trio family RhoGEFs [plasma membrane] (Drosophila melanogaster)
TRIO family RhoGEFs [cytosol] (Drosophila melanogaster)
trio [cytosol] (Drosophila melanogaster)
TRIO family RhoGEFs [cytosol] (Drosophila melanogaster)
trio [cytosol] (Drosophila melanogaster)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Drosophila melanogaster)
Signaling by Rho GTPases (Drosophila melanogaster)
RHO GTPase cycle (Drosophila melanogaster)
RAC1 GTPase cycle (Drosophila melanogaster)
RAC1 GEFs activate RAC1 (Drosophila melanogaster)
RAC1 GEFs [cytosol] (Drosophila melanogaster)
trio [cytosol] (Drosophila melanogaster)
RHOA GTPase cycle (Drosophila melanogaster)
RHOA GEFs activate RHOA (Drosophila melanogaster)
RHOA GEFs [cytosol] (Drosophila melanogaster)
trio [cytosol] (Drosophila melanogaster)
RHOG GTPase cycle (Drosophila melanogaster)
RHOG GEFs activate RHOG (Drosophila melanogaster)
RHOG GEFs [cytosol] (Drosophila melanogaster)
trio [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q7KVD1
Gene Names
trio
Reference Genes
BioGPS Gene:43974 trio
ENSEMBL:FBgn0024277
FlyBase:FBgn0024277
Monarch:43974 trio
NCBI Gene:43974 trio
UCSC:Q7KVD1 trio
Reference Transcript
RefSeq:NM_143703.3 trio
RefSeq:NM_167847.2 trio
Other Identifiers
147954_at
147955_at
1635047_s_at
43974
GO:0000166
GO:0003824
GO:0005085
GO:0005515
GO:0005524
GO:0005737
GO:0005886
GO:0007010
GO:0007411
GO:0007412
GO:0007417
GO:0007422
GO:0007480
GO:0016319
GO:0016740
GO:0019898
GO:0030036
GO:0030424
GO:0030426
GO:0031234
GO:0031532
GO:0035025
GO:0035556
GO:0043226
GO:0043229
GO:0045887
GO:0048856
GO:0050770
GO:0098772
Participates
as a candidate of
RHOA GEFs [cytosol] (Drosophila melanogaster)
RAC1 GEFs [cytosol] (Drosophila melanogaster)
as a member of
RHOG GEFs [cytosol] (Drosophila melanogaster)
TRIO family RhoGEFs [cytosol] (Drosophila melanogaster)
GEFs [cytosol] (Drosophila melanogaster)
as an input of
EPHB2 binds KALRN (Drosophila melanogaster)
as a component of
EFNBs:p-EPHBs:KALRN [plasma membrane] (Drosophila melanogaster)
Other forms of this molecule
trio [cytosol]
trio [cytosol]
trio [cytosol]
trio [cytosol]
trio [cytosol]
Inferred From
KALRN [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_651960.2
,
NP_728560.1
ENSEMBL
FBtr0072644
,
FBtr0072645
,
FBpp0072540
,
FBpp0072539
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q24568 NETB
0.462
2
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