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phospho-Spt5 [nucleoplasm]
Stable Identifier
R-DME-3009372
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
nucleoplasm
Synonyms
p-SUPT5H, Q9V460
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Drosophila melanogaster)
RNA Polymerase II Transcription (Drosophila melanogaster)
Generic Transcription Pathway (Drosophila melanogaster)
Transcriptional Regulation by TP53 (Drosophila melanogaster)
TP53 Regulates Transcription of DNA Repair Genes (Drosophila melanogaster)
CCNK:CDK12 binds RNA Pol II at DNA repair genes (Drosophila melanogaster)
CCNK:CDK12:Elongation Complex at DNA Repair Genes [nucleoplasm] (Drosophila melanogaster)
Elongation Complex at DNA Repair Genes [nucleoplasm] (Drosophila melanogaster)
Hyperphosphorylated RNA Pol II at DNA repair genes [nucleoplasm] (Drosophila melanogaster)
DSIF complex [nucleoplasm] (Drosophila melanogaster)
phospho-Spt5 [nucleoplasm] (Drosophila melanogaster)
Elongation Complex at DNA Repair Genes [nucleoplasm] (Drosophila melanogaster)
Hyperphosphorylated RNA Pol II at DNA repair genes [nucleoplasm] (Drosophila melanogaster)
DSIF complex [nucleoplasm] (Drosophila melanogaster)
phospho-Spt5 [nucleoplasm] (Drosophila melanogaster)
CDK12 phosphorylates RNA Pol II CTD at DNA repair genes (Drosophila melanogaster)
CCNK:CDK12:CDK12-Phosphorylated Elongation Complex at DNA repair genes [nucleoplasm] (Drosophila melanogaster)
CDK12-Phosphorylated Elongation Complex [nucleoplasm] (Drosophila melanogaster)
CDK12-phosphorylated RNA Pol II at DNA repair genes [nucleoplasm] (Drosophila melanogaster)
DSIF complex [nucleoplasm] (Drosophila melanogaster)
phospho-Spt5 [nucleoplasm] (Drosophila melanogaster)
CCNK:CDK12:Elongation Complex at DNA Repair Genes [nucleoplasm] (Drosophila melanogaster)
Elongation Complex at DNA Repair Genes [nucleoplasm] (Drosophila melanogaster)
Hyperphosphorylated RNA Pol II at DNA repair genes [nucleoplasm] (Drosophila melanogaster)
DSIF complex [nucleoplasm] (Drosophila melanogaster)
phospho-Spt5 [nucleoplasm] (Drosophila melanogaster)
RNA Pol II CTD phosphorylation and interaction with CE (Drosophila melanogaster)
SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) (Drosophila melanogaster)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Drosophila melanogaster)
phospho-Spt5 [nucleoplasm] (Drosophila melanogaster)
phospho-Spt5 [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II Pre-transcription Events (Drosophila melanogaster)
2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing (Drosophila melanogaster)
Paused processive elongation complex [nucleoplasm] (Drosophila melanogaster)
DSIF complex [nucleoplasm] (Drosophila melanogaster)
phospho-Spt5 [nucleoplasm] (Drosophila melanogaster)
Processive elongation complex [nucleoplasm] (Drosophila melanogaster)
DSIF complex [nucleoplasm] (Drosophila melanogaster)
phospho-Spt5 [nucleoplasm] (Drosophila melanogaster)
7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest (Drosophila melanogaster)
Processive elongation complex [nucleoplasm] (Drosophila melanogaster)
DSIF complex [nucleoplasm] (Drosophila melanogaster)
phospho-Spt5 [nucleoplasm] (Drosophila melanogaster)
Abortive termination of early transcription elongation by DSIF:NELF (Drosophila melanogaster)
DSIF:NELF:early elongation complex [nucleoplasm] (Drosophila melanogaster)
RNA Pol II (hypophosphorylated) complex bound to DSIF protein [nucleoplasm] (Drosophila melanogaster)
DSIF complex [nucleoplasm] (Drosophila melanogaster)
phospho-Spt5 [nucleoplasm] (Drosophila melanogaster)
Abortive termination of elongation after arrest (Drosophila melanogaster)
Aborted elongation complex after arrest [nucleoplasm] (Drosophila melanogaster)
DSIF complex [nucleoplasm] (Drosophila melanogaster)
phospho-Spt5 [nucleoplasm] (Drosophila melanogaster)
Processive elongation complex [nucleoplasm] (Drosophila melanogaster)
DSIF complex [nucleoplasm] (Drosophila melanogaster)
phospho-Spt5 [nucleoplasm] (Drosophila melanogaster)
Formation of DSIF complex (Drosophila melanogaster)
DSIF complex [nucleoplasm] (Drosophila melanogaster)
phospho-Spt5 [nucleoplasm] (Drosophila melanogaster)
phospho-Spt5 [nucleoplasm] (Drosophila melanogaster)
Resumption of elongation after recovery from pausing (Drosophila melanogaster)
Paused processive elongation complex [nucleoplasm] (Drosophila melanogaster)
DSIF complex [nucleoplasm] (Drosophila melanogaster)
phospho-Spt5 [nucleoplasm] (Drosophila melanogaster)
Processive elongation complex [nucleoplasm] (Drosophila melanogaster)
DSIF complex [nucleoplasm] (Drosophila melanogaster)
phospho-Spt5 [nucleoplasm] (Drosophila melanogaster)
TFIIS-mediated recovery of elongation from arrest (Drosophila melanogaster)
Processive elongation complex [nucleoplasm] (Drosophila melanogaster)
DSIF complex [nucleoplasm] (Drosophila melanogaster)
phospho-Spt5 [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II Transcription Elongation (Drosophila melanogaster)
Addition of nucleotides leads to transcript elongation (Drosophila melanogaster)
Elongation complex [nucleoplasm] (Drosophila melanogaster)
Early elongation complex with hyperphosphorylated Pol II CTD [nucleoplasm] (Drosophila melanogaster)
DSIF complex [nucleoplasm] (Drosophila melanogaster)
phospho-Spt5 [nucleoplasm] (Drosophila melanogaster)
Processive elongation complex [nucleoplasm] (Drosophila melanogaster)
DSIF complex [nucleoplasm] (Drosophila melanogaster)
phospho-Spt5 [nucleoplasm] (Drosophila melanogaster)
Formation of RNA Pol II elongation complex (Drosophila melanogaster)
Recruitment of elongation factors to form elongation complex (Drosophila melanogaster)
Early elongation complex with hyperphosphorylated Pol II CTD [nucleoplasm] (Drosophila melanogaster)
DSIF complex [nucleoplasm] (Drosophila melanogaster)
phospho-Spt5 [nucleoplasm] (Drosophila melanogaster)
Elongation complex [nucleoplasm] (Drosophila melanogaster)
Early elongation complex with hyperphosphorylated Pol II CTD [nucleoplasm] (Drosophila melanogaster)
DSIF complex [nucleoplasm] (Drosophila melanogaster)
phospho-Spt5 [nucleoplasm] (Drosophila melanogaster)
Formation of the Early Elongation Complex (Drosophila melanogaster)
DSIF complex binds to RNA Pol II (hypophosphorylated) (Drosophila melanogaster)
DSIF complex [nucleoplasm] (Drosophila melanogaster)
phospho-Spt5 [nucleoplasm] (Drosophila melanogaster)
RNA Pol II (hypophosphorylated) complex bound to DSIF protein [nucleoplasm] (Drosophila melanogaster)
DSIF complex [nucleoplasm] (Drosophila melanogaster)
phospho-Spt5 [nucleoplasm] (Drosophila melanogaster)
Formation of DSIF:NELF:early elongation complex (Drosophila melanogaster)
DSIF:NELF:early elongation complex [nucleoplasm] (Drosophila melanogaster)
RNA Pol II (hypophosphorylated) complex bound to DSIF protein [nucleoplasm] (Drosophila melanogaster)
DSIF complex [nucleoplasm] (Drosophila melanogaster)
phospho-Spt5 [nucleoplasm] (Drosophila melanogaster)
RNA Pol II (hypophosphorylated) complex bound to DSIF protein [nucleoplasm] (Drosophila melanogaster)
DSIF complex [nucleoplasm] (Drosophila melanogaster)
phospho-Spt5 [nucleoplasm] (Drosophila melanogaster)
Pol II elongation complex moves on the template as transcript elongates (Drosophila melanogaster)
Elongation complex prior to separation [nucleoplasm] (Drosophila melanogaster)
DSIF complex [nucleoplasm] (Drosophila melanogaster)
phospho-Spt5 [nucleoplasm] (Drosophila melanogaster)
Processive elongation complex [nucleoplasm] (Drosophila melanogaster)
DSIF complex [nucleoplasm] (Drosophila melanogaster)
phospho-Spt5 [nucleoplasm] (Drosophila melanogaster)
Separation of elongating transcript from template (Drosophila melanogaster)
Elongation complex prior to separation [nucleoplasm] (Drosophila melanogaster)
DSIF complex [nucleoplasm] (Drosophila melanogaster)
phospho-Spt5 [nucleoplasm] (Drosophila melanogaster)
Elongation complex with separated and uncleaved transcript [nucleoplasm] (Drosophila melanogaster)
DSIF complex [nucleoplasm] (Drosophila melanogaster)
phospho-Spt5 [nucleoplasm] (Drosophila melanogaster)
RNA polymerase II transcribes snRNA genes (Drosophila melanogaster)
Pre-snRNA transcript initiation, Integrator binding, LEC binding (Drosophila melanogaster)
DSIF complex [nucleoplasm] (Drosophila melanogaster)
phospho-Spt5 [nucleoplasm] (Drosophila melanogaster)
Metabolism of RNA (Drosophila melanogaster)
mRNA Capping (Drosophila melanogaster)
Capping complex formation (Drosophila melanogaster)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Drosophila melanogaster)
phospho-Spt5 [nucleoplasm] (Drosophila melanogaster)
Capping complex (initial) [nucleoplasm] (Drosophila melanogaster)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Drosophila melanogaster)
phospho-Spt5 [nucleoplasm] (Drosophila melanogaster)
Dissociation of transcript with 5'-GMP from GT (Drosophila melanogaster)
Capping complex (GpppN..) [nucleoplasm] (Drosophila melanogaster)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Drosophila melanogaster)
phospho-Spt5 [nucleoplasm] (Drosophila melanogaster)
Capping complex (with freed 5'- GMP) [nucleoplasm] (Drosophila melanogaster)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Drosophila melanogaster)
phospho-Spt5 [nucleoplasm] (Drosophila melanogaster)
Formation of the CE:GMP intermediate complex (Drosophila melanogaster)
Capping complex (intermediate) [nucleoplasm] (Drosophila melanogaster)
Covalent CE:GMP intermediate complex [nucleoplasm] (Drosophila melanogaster)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Drosophila melanogaster)
phospho-Spt5 [nucleoplasm] (Drosophila melanogaster)
Capping complex (hydrolyzed) [nucleoplasm] (Drosophila melanogaster)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Drosophila melanogaster)
phospho-Spt5 [nucleoplasm] (Drosophila melanogaster)
Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme (Drosophila melanogaster)
Capping complex (hydrolyzed) [nucleoplasm] (Drosophila melanogaster)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Drosophila melanogaster)
phospho-Spt5 [nucleoplasm] (Drosophila melanogaster)
Capping complex (initial) [nucleoplasm] (Drosophila melanogaster)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Drosophila melanogaster)
phospho-Spt5 [nucleoplasm] (Drosophila melanogaster)
Methylation of GMP-cap by RNA Methyltransferase (Drosophila melanogaster)
Capping complex (with freed 5'- GMP) [nucleoplasm] (Drosophila melanogaster)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Drosophila melanogaster)
phospho-Spt5 [nucleoplasm] (Drosophila melanogaster)
phospho-Spt5 [nucleoplasm] (Drosophila melanogaster)
SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) (Drosophila melanogaster)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Drosophila melanogaster)
phospho-Spt5 [nucleoplasm] (Drosophila melanogaster)
phospho-Spt5 [nucleoplasm] (Drosophila melanogaster)
Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA (Drosophila melanogaster)
Capping complex (intermediate) [nucleoplasm] (Drosophila melanogaster)
Covalent CE:GMP intermediate complex [nucleoplasm] (Drosophila melanogaster)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Drosophila melanogaster)
phospho-Spt5 [nucleoplasm] (Drosophila melanogaster)
Capping complex (GpppN..) [nucleoplasm] (Drosophila melanogaster)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Drosophila melanogaster)
phospho-Spt5 [nucleoplasm] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9V460
Gene Names
Spt5
Reference Genes
BioGPS Gene:53442 Spt5
CTD Gene:53442 Spt5
ENSEMBL:FBgn0040273
Flybase:FBgn0040273
KEGG Gene (Drosophila melanogaster):Dmel_CG7626 Spt5
Monarch:53442 Spt5
NCBI Gene:53442 Spt5
UCSC:Q9V460 Spt5
Reference Transcript
RefSeq:NM_144353.4 Spt5
Other Identifiers
152632_at
1626448_at
53442
GO:0000122
GO:0000993
GO:0003682
GO:0003723
GO:0003729
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0005700
GO:0005703
GO:0005705
GO:0006325
GO:0006351
GO:0006354
GO:0006355
GO:0006357
GO:0006368
GO:0007549
GO:0008023
GO:0032044
GO:0032784
GO:0032785
GO:0032786
GO:0043226
GO:0044877
GO:0045944
GO:0046982
GO:0140673
Participates
as an input of
Formation of DSIF complex (Drosophila melanogaster)
SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) (Drosophila melanogaster)
as an output of
Methylation of GMP-cap by RNA Methyltransferase (Drosophila melanogaster)
as a component of
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Drosophila melanogaster)
DSIF complex [nucleoplasm] (Drosophila melanogaster)
Inferred From
p-SUPT5H [nucleoplasm]
(Homo sapiens)
Modified Residues
Name
phosphorylated residue at unknown position
PsiMod Name
phosphorylated residue [MOD:00696]
PsiMod Definition
A protein modification that effectively replaces a hydrogen atom with a phosphate group.
Cross References
RefSeq
NP_652610.1
Flybase
FBgn0040273
PRO
Q9V460
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