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KDM4B [nucleoplasm]
Stable Identifier
R-DME-3214396-2
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
nucleoplasm
Synonyms
Q9V6L0
Locations in the PathwayBrowser
Expand all
DNA Repair (Drosophila melanogaster)
DNA Double-Strand Break Repair (Drosophila melanogaster)
DNA Double Strand Break Response (Drosophila melanogaster)
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks (Drosophila melanogaster)
ATM phosphorylates HERC2 (Drosophila melanogaster)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+:HERC2:PIAS4 [nucleoplasm] (Drosophila melanogaster)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+ [nucleoplasm] (Drosophila melanogaster)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1 [nucleoplasm] (Drosophila melanogaster)
Homologues of KDM4B [nucleoplasm] (Drosophila melanogaster)
KDM4B [nucleoplasm] (Drosophila melanogaster)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+:p-T4827-HERC2:PIAS4 [nucleoplasm] (Drosophila melanogaster)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+ [nucleoplasm] (Drosophila melanogaster)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1 [nucleoplasm] (Drosophila melanogaster)
Homologues of KDM4B [nucleoplasm] (Drosophila melanogaster)
KDM4B [nucleoplasm] (Drosophila melanogaster)
HERC2 and PIAS4 are recruited to DNA DSBs (Drosophila melanogaster)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+ [nucleoplasm] (Drosophila melanogaster)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1 [nucleoplasm] (Drosophila melanogaster)
Homologues of KDM4B [nucleoplasm] (Drosophila melanogaster)
KDM4B [nucleoplasm] (Drosophila melanogaster)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+:HERC2:PIAS4 [nucleoplasm] (Drosophila melanogaster)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+ [nucleoplasm] (Drosophila melanogaster)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1 [nucleoplasm] (Drosophila melanogaster)
Homologues of KDM4B [nucleoplasm] (Drosophila melanogaster)
KDM4B [nucleoplasm] (Drosophila melanogaster)
HERC2 facilitates UBE2N:UBE2V2 binding to RNF8 (Drosophila melanogaster)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:PIAS4 [nucleoplasm] (Drosophila melanogaster)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1 [nucleoplasm] (Drosophila melanogaster)
Homologues of KDM4B [nucleoplasm] (Drosophila melanogaster)
KDM4B [nucleoplasm] (Drosophila melanogaster)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:PIAS4 [nucleoplasm] (Drosophila melanogaster)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1 [nucleoplasm] (Drosophila melanogaster)
Homologues of KDM4B [nucleoplasm] (Drosophila melanogaster)
KDM4B [nucleoplasm] (Drosophila melanogaster)
KDM4A,B bind H4K20Me2 (Drosophila melanogaster)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1 [nucleoplasm] (Drosophila melanogaster)
Homologues of KDM4B [nucleoplasm] (Drosophila melanogaster)
KDM4B [nucleoplasm] (Drosophila melanogaster)
Homologues of KDM4B [nucleoplasm] (Drosophila melanogaster)
KDM4B [nucleoplasm] (Drosophila melanogaster)
RNF8 and RNF168 ubiquitinate H2AFX (Drosophila melanogaster)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4 [nucleoplasm] (Drosophila melanogaster)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1 [nucleoplasm] (Drosophila melanogaster)
Homologues of KDM4B [nucleoplasm] (Drosophila melanogaster)
KDM4B [nucleoplasm] (Drosophila melanogaster)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4 [nucleoplasm] (Drosophila melanogaster)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:PIAS4 [nucleoplasm] (Drosophila melanogaster)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1 [nucleoplasm] (Drosophila melanogaster)
Homologues of KDM4B [nucleoplasm] (Drosophila melanogaster)
KDM4B [nucleoplasm] (Drosophila melanogaster)
RNF8 and RNF168 ubiquitinate KDM4A,B (Drosophila melanogaster)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4 [nucleoplasm] (Drosophila melanogaster)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1 [nucleoplasm] (Drosophila melanogaster)
Homologues of KDM4B [nucleoplasm] (Drosophila melanogaster)
KDM4B [nucleoplasm] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Signaling by Nuclear Receptors (Drosophila melanogaster)
ESR-mediated signaling (Drosophila melanogaster)
Estrogen-dependent gene expression (Drosophila melanogaster)
ESR1:ESTG and KDM4B bind H3K9me3 target gene enhancers (Drosophila melanogaster)
Homologues of KDM4B [nucleoplasm] (Drosophila melanogaster)
KDM4B [nucleoplasm] (Drosophila melanogaster)
KDM4B-regulated genes:H3K9me3 nucleosome:ESR1:ESTG:KDM4B [nucleoplasm] (Drosophila melanogaster)
Homologues of KDM4B [nucleoplasm] (Drosophila melanogaster)
KDM4B [nucleoplasm] (Drosophila melanogaster)
KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers (Drosophila melanogaster)
Homologues of KDM4B [nucleoplasm] (Drosophila melanogaster)
KDM4B [nucleoplasm] (Drosophila melanogaster)
KDM4B-regulated genes:H3K9me3 nucleosome:ESR1:ESTG:KDM4B [nucleoplasm] (Drosophila melanogaster)
Homologues of KDM4B [nucleoplasm] (Drosophila melanogaster)
KDM4B [nucleoplasm] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9V6L0
Reference Genes
BioGPS Gene:318918
ENSEMBL:FBgn0053182
FlyBase:FBgn0053182
KEGG Gene (Drosophila melanogaster):Dmel_CG33182
Monarch:318918
NCBI Gene:318918
UCSC:Q9V6L0
Reference Transcript
RefSeq:NM_001169667.2
RefSeq:NM_176164.4
RefSeq:NM_001169666.2
RefSeq:NM_001169668.2
Other Identifiers
1629788_at
318918
GO:0000785
GO:0003824
GO:0005634
GO:0005694
GO:0006325
GO:0006338
GO:0006351
GO:0006355
GO:0010468
GO:0016491
GO:0016706
GO:0032452
GO:0032454
GO:0036211
GO:0043226
GO:0045892
GO:0046872
GO:0051213
GO:0051864
GO:0140096
GO:0140680
GO:0140681
GO:0140684
Participates
as a member of
Homologues of KDM4B [nucleoplasm] (Drosophila melanogaster)
Other forms of this molecule
KDM4C [nucleoplasm]
K48PolyUb-KDM4B [nucleoplasm]
Inferred From
KDM4B [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_001163138.1
,
NP_788344.2
,
NP_001163139.1
,
NP_001163137.1
Flybase
FBgn0053182
PRO
Q9V6L0
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