ROK binds to activated RHO1:GTP

Stable Identifier
R-DME-350388
Type
Reaction [binding]
Species
Drosophila melanogaster
Compartment
cytosol, plasma membrane
ReviewStatus
5/5
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ROK binds to activated RHO1:GTP
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Rho-kinase (ROK) aka Drok binds to activated Rho GTPase (RHO1:GTP) and is itself activated. The conserved Rho-binding site in ROK is the area of interaction.
Literature References
PubMed ID Title Journal Year
11301004 Drosophila Rho-associated kinase (Drok) links Frizzled-mediated planar cell polarity signaling to the actin cytoskeleton

Winter, CG, Axelrod, JD, Ballew, A, Royou, A, Wang, B, Karess, R, Luo, L

Cell 2001
10570971 Identification and characterization of Drosophila homolog of Rho-kinase

Amano, M, Nishida, Y, Kaibuchi, K, Mizuno, T

Gene 1999
Participants
Input
Output
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as an event of
Authored
Williams, MG  (2008-05-20)
Reviewed
Axelrod, JD  (2009-11-19)
Created
Williams, MG  (2008-05-19)
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