Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
DGO [cytosol]
Stable Identifier
R-DME-351073
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Drosophila signaling pathways (Drosophila melanogaster)
Planar Cell Polarity pathway (Drosophila melanogaster)
Activation of Downstream Effectors (Drosophila melanogaster)
Activation of RAC1:GTP by FZ:DSH complex (Drosophila melanogaster)
DSH binds to RAC1:GTP (Drosophila melanogaster)
PK:VANG:STAN dimer:FZ:DSH:DGO [plasma membrane] (Drosophila melanogaster)
DGO [cytosol] (Drosophila melanogaster)
PK:VANG:STAN dimer:FZ:DSH:DGO:RAC1:GTP [plasma membrane] (Drosophila melanogaster)
DGO [cytosol] (Drosophila melanogaster)
RAC1:GTP and MSN activate HEP (Drosophila melanogaster)
PK:VANG:STAN dimer:FZ:DSH:DGO:RAC1:GTP [plasma membrane] (Drosophila melanogaster)
DGO [cytosol] (Drosophila melanogaster)
RHO1 signalling (Drosophila melanogaster)
Activation of RHO1 by FZ:DSH complex (Drosophila melanogaster)
DSH binds to DAAM (Drosophila melanogaster)
PK:VANG:STAN dimer:FZ:DSH:DGO [plasma membrane] (Drosophila melanogaster)
DGO [cytosol] (Drosophila melanogaster)
PK:VANG:STAN dimer:FZ:DSH:DGO:DAAM [plasma membrane] (Drosophila melanogaster)
DGO [cytosol] (Drosophila melanogaster)
RHO1:GTP binds to activated DAAM (Drosophila melanogaster)
PK:VANG:STAN dimer:FZ:DSH:DGO:DAAM [plasma membrane] (Drosophila melanogaster)
DGO [cytosol] (Drosophila melanogaster)
PK:VANG:STAN dimer:FZ:DSH:DGO:DAAM:RHO1:GTP [plasma membrane] (Drosophila melanogaster)
DGO [cytosol] (Drosophila melanogaster)
ROK binds to activated RHO1:GTP (Drosophila melanogaster)
PK:VANG:STAN dimer:FZ:DSH:DGO:DAAM:RHO1:GTP [plasma membrane] (Drosophila melanogaster)
DGO [cytosol] (Drosophila melanogaster)
PK:VANG:STAN dimer:FZ:DSH:DGO:DAAM:RHO1:GTP:ROK [plasma membrane] (Drosophila melanogaster)
DGO [cytosol] (Drosophila melanogaster)
Activation of non-muscle Myosin II (Drosophila melanogaster)
ROK phosphorylates MBS (Drosophila melanogaster)
PK:VANG:STAN dimer:FZ:DSH:DGO:DAAM:RHO1:GTP:ROK [plasma membrane] (Drosophila melanogaster)
DGO [cytosol] (Drosophila melanogaster)
ROK phosphorylates SQH (Drosophila melanogaster)
PK:VANG:STAN dimer:FZ:DSH:DGO:DAAM:RHO1:GTP:ROK [plasma membrane] (Drosophila melanogaster)
DGO [cytosol] (Drosophila melanogaster)
Inhibition of actin polymerization (Drosophila melanogaster)
VANG, IN, FY, and FRTZ colocalise at the plasma membrane (Drosophila melanogaster)
PK:VANG:STAN dimer:FZ:DSH:DGO [plasma membrane] (Drosophila melanogaster)
DGO [cytosol] (Drosophila melanogaster)
Formation and asymmetric localisation of transmembrane complexes (Drosophila melanogaster)
DGO binds to DSH (Drosophila melanogaster)
DGO [cytosol] (Drosophila melanogaster)
PK:VANG:STAN dimer:FZ:DSH:DGO [plasma membrane] (Drosophila melanogaster)
DGO [cytosol] (Drosophila melanogaster)
Negative feedback loop regulates asymmetric localisation (Drosophila melanogaster)
DGO binds to PK (Drosophila melanogaster)
DGO [cytosol] (Drosophila melanogaster)
PK:DGO [cytosol] (Drosophila melanogaster)
DGO [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q7JUF2 dgo
Gene Names
dgo, CG12342, Dmel_CG12342
Reference Genes
BioGPS Gene:36139 dgo
CTD Gene:36139 dgo
KEGG Gene (Drosophila melanogaster):Dmel_CG12342 dgo
Monarch:36139 dgo
NCBI Gene:36139 dgo
UCSC:Q7JUF2 dgo
Reference Transcript
RefSeq:NM_136770.2 dgo
RefSeq:NM_165800.2 dgo
Other Identifiers
153620_at
1638064_a_at
36139
GO:0001737
GO:0005515
GO:0005737
GO:0005829
GO:0007163
GO:0016318
GO:0030154
GO:0042067
GO:0048856
Participates
as a component of
PK:VANG:STAN dimer:FZ:DSH:DGO:DAAM [plasma membrane] (Drosophila melanogaster)
PK:VANG:STAN dimer:FZ:DSH:DGO:DAAM:RHO1:GTP:ROK [plasma membrane] (Drosophila melanogaster)
PK:VANG:STAN dimer:FZ:DSH:DGO:DAAM:RHO1:GTP [plasma membrane] (Drosophila melanogaster)
PK:DGO [cytosol] (Drosophila melanogaster)
PK:VANG:STAN dimer:FZ:DSH:DGO [plasma membrane] (Drosophila melanogaster)
PK:VANG:STAN dimer:FZ:DSH:DGO:RAC1:GTP [plasma membrane] (Drosophila melanogaster)
as an input of
DGO binds to PK (Drosophila melanogaster)
DGO binds to DSH (Drosophila melanogaster)
Cross References
RefSeq
NP_724973.1
,
NP_610614.1
Flybase
FBgn0086898
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P51140 dsh
14
dsh [cytosol]
(R-DME-4652689)
dsh [cytosol]
(R-DME-4652688)
dsh [cytosol]
(R-DME-4641157)
dsh [cytosol]
(R-DME-201678)
dsh [cytosol]
(R-DME-201687)
dsh [cytosol]
(R-DME-201694)
phospho-dsh [clathrin-coated endocytic vesicle]
(R-DME-5138444)
DSH [cytosol]
(R-DME-205749)
phospho-dsh [cytosol]
(R-DME-201706)
phospho-dsh [cytosol]
(R-DME-201700)
phospho-dsh [cytosol]
(R-DME-201680)
phospho-dsh [cytosol]
(R-DME-3772398)
phospho-dsh [cytosol]
(R-DME-3772400)
phospho-dsh [cytosol]
(R-DME-3772396)
0.581
5
UniProt:Q9VS38
1
MED4 [nucleoplasm]
(R-DME-350263)
0.488
2
UniProt:Q9W3Z4 Q9W3Z4
0.488
2
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text