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mbc [cytosol]
Stable Identifier
R-DME-372654
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
DOCK1, A0A0B4K7Q6
Locations in the PathwayBrowser
Expand all
Developmental Biology (Drosophila melanogaster)
Nervous system development (Drosophila melanogaster)
Axon guidance (Drosophila melanogaster)
Netrin-1 signaling (Drosophila melanogaster)
DCC mediated attractive signaling (Drosophila melanogaster)
Activation of Cdc42 (Drosophila melanogaster)
DOCK1,TRIO [cytosol] (Drosophila melanogaster)
mbc [cytosol] (Drosophila melanogaster)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Drosophila melanogaster)
DOCK1,TRIO [cytosol] (Drosophila melanogaster)
mbc [cytosol] (Drosophila melanogaster)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP [plasma membrane] (Drosophila melanogaster)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Drosophila melanogaster)
DOCK1,TRIO [cytosol] (Drosophila melanogaster)
mbc [cytosol] (Drosophila melanogaster)
Activation of Rac1 (Drosophila melanogaster)
DOCK1,TRIO [cytosol] (Drosophila melanogaster)
mbc [cytosol] (Drosophila melanogaster)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Drosophila melanogaster)
DOCK1,TRIO [cytosol] (Drosophila melanogaster)
mbc [cytosol] (Drosophila melanogaster)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:RAC1:GTP [plasma membrane] (Drosophila melanogaster)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Drosophila melanogaster)
DOCK1,TRIO [cytosol] (Drosophila melanogaster)
mbc [cytosol] (Drosophila melanogaster)
RhoGTPase GEF's recruited to DCC (Drosophila melanogaster)
DOCK1,TRIO [cytosol] (Drosophila melanogaster)
mbc [cytosol] (Drosophila melanogaster)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Drosophila melanogaster)
DOCK1,TRIO [cytosol] (Drosophila melanogaster)
mbc [cytosol] (Drosophila melanogaster)
Hemostasis (Drosophila melanogaster)
Factors involved in megakaryocyte development and platelet production (Drosophila melanogaster)
DOCKs bind to RhoGEFs (Drosophila melanogaster)
DOCK-GEFs [cytosol] (Drosophila melanogaster)
mbc [cytosol] (Drosophila melanogaster)
DOCK-GEFs:RAC1, CDC42 [cytosol] (Drosophila melanogaster)
DOCK-GEFs [cytosol] (Drosophila melanogaster)
mbc [cytosol] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Signaling by Non-Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by PTK6 (Drosophila melanogaster)
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Drosophila melanogaster)
Activation of RAC1 by the PXN:CRK complex (Drosophila melanogaster)
p-Y31,Y118-PXN:CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Drosophila melanogaster)
CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Drosophila melanogaster)
mbc [cytosol] (Drosophila melanogaster)
Phosphorylated PXN recruits the CRK complex (Drosophila melanogaster)
CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Drosophila melanogaster)
mbc [cytosol] (Drosophila melanogaster)
p-Y31,Y118-PXN:CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Drosophila melanogaster)
CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Drosophila melanogaster)
mbc [cytosol] (Drosophila melanogaster)
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by VEGF (Drosophila melanogaster)
VEGFA-VEGFR2 Pathway (Drosophila melanogaster)
DOCK180:ELMO binds CRK (Drosophila melanogaster)
CRK:DOCK180:ELMO1,ELMO2:VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Drosophila melanogaster)
CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Drosophila melanogaster)
mbc [cytosol] (Drosophila melanogaster)
DOCK180:ELMO1,ELMO2 [cytosol] (Drosophila melanogaster)
mbc [cytosol] (Drosophila melanogaster)
DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Drosophila melanogaster)
CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Drosophila melanogaster)
mbc [cytosol] (Drosophila melanogaster)
CRK:DOCK180:ELMO1,ELMO2:VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Drosophila melanogaster)
CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Drosophila melanogaster)
mbc [cytosol] (Drosophila melanogaster)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Drosophila melanogaster)
Signaling by Rho GTPases (Drosophila melanogaster)
RHO GTPase cycle (Drosophila melanogaster)
RAC1 GTPase cycle (Drosophila melanogaster)
RAC1 GEFs activate RAC1 (Drosophila melanogaster)
RAC1 GEFs [cytosol] (Drosophila melanogaster)
mbc [cytosol] (Drosophila melanogaster)
RHOG GTPase cycle (Drosophila melanogaster)
RHOG binds effectors at the plasma membrane (Drosophila melanogaster)
RHOG plasma membrane effectors [cytosol] (Drosophila melanogaster)
mbc [cytosol] (Drosophila melanogaster)
RHOG:GTP:RHOG plasma membrane effectors [plasma membrane] (Drosophila melanogaster)
RHOG plasma membrane effectors [cytosol] (Drosophila melanogaster)
mbc [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:A0A0B4K7Q6
Gene Names
mbc
Reference Genes
BioGPS Gene:42817 mbc
CTD Gene:42817 mbc
ENSEMBL:FBgn0015513
FlyBase:FBgn0015513
KEGG Gene (Drosophila melanogaster):Dmel_CG10379 mbc
Monarch:42817 mbc
NCBI Gene:42817 mbc
Reference Transcript
RefSeq:NM_001260338.2 mbc
Other Identifiers
143808_at
1631013_at
42817
GO:0000902
GO:0001726
GO:0005085
GO:0005515
GO:0005737
GO:0005886
GO:0007010
GO:0007264
GO:0007298
GO:0007391
GO:0007417
GO:0007520
GO:0007523
GO:0016203
GO:0016477
GO:0022414
GO:0023052
GO:0030036
GO:0030154
GO:0031234
GO:0031267
GO:0035022
GO:0035212
GO:0046330
GO:0046529
GO:0048010
GO:0048856
GO:0048870
GO:0061327
GO:0090630
GO:0098772
GO:1903688
Participates
as a candidate of
RAC1 GEFs [cytosol] (Drosophila melanogaster)
as a member of
RHOG plasma membrane effectors [cytosol] (Drosophila melanogaster)
DOCK-GEFs [cytosol] (Drosophila melanogaster)
DOCK1,TRIO [cytosol] (Drosophila melanogaster)
as a component of
DOCK180:ELMO1,ELMO2 [cytosol] (Drosophila melanogaster)
CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Drosophila melanogaster)
Other forms of this molecule
mbc [cytosol]
mbc [cytosol]
mbc [extracellular region]
mbc [specific granule lumen]
Inferred From
DOCK1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001247267.1
Flybase
FBgn0015513
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