Reactome | SUMO2-C93-UBE2I [nucleoplasm]

SUMO2-C93-UBE2I [nucleoplasm]

Stable Identifier

R-DME-3730619

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

nucleoplasm

Synonyms

Q7KNM2

Locations in the PathwayBrowser

Expand all

DNA Repair (Drosophila melanogaster)

- Nucleotide Excision Repair (Drosophila melanogaster)
  - Global Genome Nucleotide Excision Repair (GG-NER) (Drosophila melanogaster)
    - Formation of Incision Complex in GG-NER (Drosophila melanogaster)
      - SUMOylation of XPC (Drosophila melanogaster)
        
        SUMO1,2,3:UBE2I [nucleoplasm] (Drosophila melanogaster)
        
        SUMO2:UBE2I [nucleoplasm] (Drosophila melanogaster)
        
        SUMO2-C93-UBE2I [nucleoplasm] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q7KNM2

Reference Genes

BioGPS Gene:33226

ENSEMBL:FBgn0010602

Flybase:FBgn0010602

KEGG Gene (Drosophila melanogaster):Dmel_CG3018

Monarch:33226

NCBI Gene:33226

Reference Transcript

Other Identifiers

153243_at

1636282_s_at

7227.FBpp0301731

AAC38964.1

AAD21970.1

AAF51487.1

AAN10499.1

AB017606

AF030444

AF218861

AGB92370.1

AGB92371.1

AY060944

AY113433

BAA34575.1

EntrezGene:33226

FBgn0010602

FBpp0077741

FBpp0077742

FBpp0301731

FBpp0301732

FBtr0078081

FBtr0078082

FBtr0310028

FBtr0310029

GO:0000003

GO:0000166

GO:0000228

GO:0000780

GO:0000940

GO:0002225

GO:0002376

GO:0003674

GO:0005515

GO:0005524

GO:0005575

GO:0005622

GO:0005623

GO:0005634

GO:0005694

GO:0005737

GO:0006464

GO:0006606

GO:0006810

GO:0006913

GO:0006959

GO:0007049

GO:0007059

GO:0007143

GO:0007165

GO:0007352

GO:0007391

GO:0008134

GO:0008150

GO:0008283

GO:0008354

GO:0009058

GO:0009790

GO:0015031

GO:0016321

GO:0016740

GO:0016925

GO:0019789

GO:0019899

GO:0030154

GO:0030721

GO:0031072

GO:0032991

GO:0033134

GO:0034641

GO:0035172

GO:0035204

GO:0035207

GO:0040011

GO:0042802

GO:0043167

GO:0043226

GO:0045611

GO:0045751

GO:0048856

GO:0048870

GO:0051091

GO:0061656

GO:0061665

GO:0071560

IPR000608

IPR016135

IPR023313

KX531808

NM_001272904.1

NM_001272905.1

NM_057630.4

NM_164385.2

NP_001259833.1

NP_001259834.1

NP_476978.1

NP_722637.1

PF00179

SM00212

UPI000007E2B9

Participant Of

hasComponent

SUMO2:UBE2I [nucleoplasm]

Other forms of this molecule

UBE2I [nucleoplasm]

SUMO3-C93-UBE2I [nucleoplasm]

UBE2I [cytosol]

UBE2I [nuclear envelope]

Inferred From

SUMO2-C93-UBE2I [nucleoplasm] (Homo sapiens)

Modified Residues

Name

Inter-chain Crosslink via S-(glycyl)-L-cysteine (Cys-Gly) at 93 and 93 (in Homo sapiens)

Coordinate

PsiMod Name

S-(glycyl)-L-cysteine (Cys-Gly)

PsiMod Definition

A protein modification that effectively crosslinks an L-cysteine residue and a glycine residue by a thioester bond to form S-glycyl-L-cysteine.

Cross References

RefSeq

NP_001259833.1, NP_722637.1, NP_476978.1, NP_001259834.1

Flybase

FBgn0010602

Interactors (58)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9N6D8 Q9N6D8			0.621	4
UniProt:P09956 ZEST			0.621	5
UniProt:Q7KNM2	5	SUMO2-C93-UBE2I [nucleoplasm] (R-DME-3730619) UBE2I [nucleoplasm] (R-DME-912481) SUMO3-C93-UBE2I [nucleoplasm] (R-DME-3730629) UBE2I [cytosol] (R-DME-4655342) UBE2I [nuclear envelope] (R-DME-4655408)	0.621	3
UniProt:O97102	6	SUMO2(1-95) [nucleoplasm] (R-DME-2990837) SUMO3(1-103) [nucleoplasm] (R-DME-2990830) UBE2I-G92-SUMO3 [nucleoplasm] (R-DME-3730611) SUMO2 [nucleoplasm] (R-DME-2984281) SUMO3 [nucleoplasm] (R-DME-2984269) UBE2I-G93-SUMO2 [nucleoplasm] (R-DME-3730625)	0.502	2
UniProt:Q9VYG4 Q9VYG4			0.488	2
UniProt:Q9VUK9 Q9VUK9			0.488	2
UniProt:Q8WS79	34	PolyUb-AR [nucleoplasm] (R-DME-6782984) phospho-p-S118-ESR1 [nucleoplasm] (R-DME-9024210) ESRRB [nucleoplasm] (R-DME-446173) ESRRG [nucleoplasm] (R-DME-446166) NR3C1-2 [nucleoplasm] (R-DME-3196175) NR3C1-1 [nucleoplasm] (R-DME-3196163) ESR1 [cytosol] (R-DME-9020968) ESR2 [cytosol] (R-DME-9020970) ESR1 [nucleoplasm] (R-DME-446168) ESR2 [nucleoplasm] (R-DME-446165) PGR [nucleoplasm] (R-DME-3008952) Me260-ESR1 [cytosol] (R-DME-9632177) ESRRA [nucleoplasm] (R-DME-446159) AR [nucleoplasm] (R-DME-446174) AR [cytosol] (R-DME-5618082) Me-PalmS-ESR2 [plasma membrane] (R-DME-9637787) Me87-PalmS-ER alpha36 [plasma membrane] (R-DME-9637786) Me260-PalmS-ESR1 [plasma membrane] (R-DME-9637788) PalmS-ER alpha36 [plasma membrane] (R-DME-9021053) PalmS-ESR2 [plasma membrane] (R-DME-9021059) PalmS-ESR1 [plasma membrane] (R-DME-9021057) PalmS-ER alpha46 [cytosol] (R-DME-9020991) PalmS-ESR2 [cytosol] (R-DME-9020979) PalmS-ESR1 [cytosol] (R-DME-9020974) PGR [cytosol] (R-DME-8948964) NR3C2 [cytosol] (R-DME-5618122) NR3C1 [cytosol] (R-DME-5618118) NR3C2-1 [nucleoplasm] (R-DME-3008717) NR3C1-9 [nucleoplasm] (R-DME-3196152) NR3C1-5 [nucleoplasm] (R-DME-3196155) NR3C1-8 [nucleoplasm] (R-DME-3196158) NR3C1-6 [nucleoplasm] (R-DME-3196159) NR3C1-7 [nucleoplasm] (R-DME-3196167) NR3C1-3 [nucleoplasm] (R-DME-3196173)	0.488	2
UniProt:Q7JUZ9 Q7JUZ9			0.488	2
UniProt:Q9VW28 Q9VW28			0.488	2
UniProt:Q9W4C1 Q9W4C1			0.488	2
UniProt:Q0E8Q6 Q0E8Q6			0.488	2
UniProt:Q9VH90	2	ZRANB1 [cytosol] (R-DME-6781939) TNFAIP3 [cytosol] (R-DME-688989)	0.488	2
UniProt:A0A0B4LET0 A0A0B4LET0			0.488	2
UniProt:C6SV36 C6SV36			0.488	2
UniProt:Q6NND8 Q6NND8			0.488	2
UniProt:Q9V813	1	MTAP [cytosol] (R-DME-1237091-2)	0.488	2
UniProt:A1Z7A8 COIL			0.488	2
UniProt:Q94513 Q94513			0.488	2
UniProt:Q9VS36 TO6BL			0.488	2
UniProt:Q9VNJ0	1	RNF4 [cytosol] (R-DME-975974)	0.488	4
UniProt:Q9W2P8 Q9W2P8			0.488	2
UniProt:Q9VZV5 CYHR1			0.488	2
UniProt:Q960J9 Q960J9			0.488	2
UniProt:Q9VHF0 Q9VHF0			0.488	2
UniProt:A1A706 A1A706			0.488	2
UniProt:Q9VM37 Q9VM37			0.488	2
UniProt:Q7JWH6 Q7JWH6			0.488	2
UniProt:Q9VFX8 Q9VFX8			0.488	2
UniProt:P48596-3 PU			0.488	2
UniProt:Q5BIG7 Q5BIG7			0.488	2
UniProt:Q9VFP2 rdx	3	SPOP [nucleoplasm] (R-DME-5635035) RDX [nucleoplasm] (R-DME-216275) SPOPL [nucleoplasm] (R-DME-5635036)	0.488	2
UniProt:Q9VBP5 Q9VBP5			0.488	2
UniProt:Q24533	5	SRY [nucleoplasm] (R-DME-5627706-6) SOX17 [nucleoplasm] (R-DME-5625834-6) SOX4 [nucleoplasm] (R-DME-5625832-6) SOX7 [nucleoplasm] (R-DME-5627712-6) SOX2 [nucleoplasm] (R-DME-452271-6)	0.488	2
UniProt:Q7JQL2 Q7JQL2			0.488	2
UniProt:Q7KN62-3 TER94			0.488	2
UniProt:Q7JR58	1	ECHS1 [mitochondrial matrix] (R-DME-54125)	0.488	2
UniProt:Q6NMX3 Q6NMX3			0.488	2
UniProt:Q9VHC0	2	RNPS1 [cytosol] (R-DME-159256) RNPS1 [nucleoplasm] (R-DME-156778)	0.488	2
UniProt:D5SHR0	1	KCTD1 [nucleoplasm] (R-DME-8864339)	0.488	2
UniProt:P51023	4	ETS1 [nucleoplasm] (R-DME-1629809) ETS2 [nucleoplasm] (R-DME-1629811) phospho-p-T38-ETS1 [nucleoplasm] (R-DME-3132720) phospho-p-T72-ETS2 [nucleoplasm] (R-DME-3132735)	0.488	2
UniProt:Q9TW27	1	ADAR [nucleoplasm] (R-DME-53939)	0.488	2
UniProt:Q9W4Z6 Q9W4Z6			0.488	2
UniProt:Q9VTT1 Q9VTT1			0.488	2
UniProt:Q9VAF2 Q9VAF2			0.488	2
UniProt:Q9W0N9 Q9W0N9			0.488	2
UniProt:Q7JR80 Q7JR80			0.488	2
UniProt:Q9W0N4 Q9W0N4			0.488	2
UniProt:Q9VVT4 Q9VVT4			0.488	4
UniProt:Q7JWW6 Q7JWW6			0.488	2
UniProt:Q7JN06 Q7JN06			0.488	2
UniProt:Q9VSB8 Q9VSB8			0.488	2
UniProt:Q8IFW4 THIOT			0.488	2
UniProt:Q7JNE1 Q7JNE1			0.488	2
UniProt:Q8T8S2	1	UPP1 [cytosol] (R-DME-73556-2)	0.488	2
UniProt:M9MRD4 M9MRD4			0.488	2
UniProt:Q7K3E9 Q7K3E9			0.488	2
UniProt:P20385-2 CF2			0.488	2
UniProt:Q8SXP8 Q8SXP8			0.488	2