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EIF2AK3 [endoplasmic reticulum membrane]
Stable Identifier
R-DME-381046
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
endoplasmic reticulum membrane
Synonyms
Q9NIV1
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Drosophila melanogaster)
Cellular responses to stress (Drosophila melanogaster)
Unfolded Protein Response (UPR) (Drosophila melanogaster)
PERK regulates gene expression (Drosophila melanogaster)
Dimerization of PERK (Drosophila melanogaster)
EIF2AK3 [endoplasmic reticulum membrane] (Drosophila melanogaster)
PERK dimer [endoplasmic reticulum membrane] (Drosophila melanogaster)
EIF2AK3 [endoplasmic reticulum membrane] (Drosophila melanogaster)
EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK (Drosophila melanogaster)
PERK dimer [endoplasmic reticulum membrane] (Drosophila melanogaster)
EIF2AK3 [endoplasmic reticulum membrane] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9NIV1
Reference Genes
BioGPS Gene:40653
ENSEMBL:FBgn0037327
Flybase:FBgn0037327
KEGG Gene (Drosophila melanogaster):Dmel_CG2087
Monarch:40653
NCBI Gene:40653
Reference Transcript
RefSeq:NM_141281.3
Other Identifiers
149333_at
1641072_at
40653
GO:0000166
GO:0000278
GO:0003824
GO:0004672
GO:0004674
GO:0004686
GO:0004694
GO:0005515
GO:0005524
GO:0005634
GO:0005737
GO:0005783
GO:0005789
GO:0005829
GO:0006417
GO:0006468
GO:0006914
GO:0006986
GO:0010389
GO:0010508
GO:0016020
GO:0016301
GO:0016310
GO:0016740
GO:0023052
GO:0034976
GO:0036211
GO:0036499
GO:0043226
GO:0045182
GO:0046330
GO:0106310
GO:0140096
Participates
as an input of
Dimerization of PERK (Drosophila melanogaster)
as a component of
PERK:BiP [endoplasmic reticulum membrane] (Drosophila melanogaster)
PERK dimer [endoplasmic reticulum membrane] (Drosophila melanogaster)
Other forms of this molecule
phospho-p-EIF2AK2 [nucleoplasm]
SUMO-EIF2AK2 [cytosol]
ISG15-EIF2AK2 [cytosol]
phospho-p-EIF2AK2 [cytosol]
EIF2AK2 [cytosol]
Inferred From
EIF2AK3 [endoplasmic reticulum membrane]
(Homo sapiens)
Cross References
RefSeq
NP_649538.1
Flybase
FBgn0037327
PRO
Q9NIV1
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P18431-3 SGG
0.597
3
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