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PHC3 [nucleoplasm]
Stable Identifier
R-DME-389116
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
nucleoplasm
Synonyms
P39769
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Drosophila melanogaster)
Cellular responses to stress (Drosophila melanogaster)
Cellular Senescence (Drosophila melanogaster)
Oxidative Stress Induced Senescence (Drosophila melanogaster)
PRC1.4 complex binds H3K27Me3 nucleosomes on CDKN2A promoter (Drosophila melanogaster)
CDKN2A Gene:H3K27Me3-Nucleosome:PRC1.4 [nucleoplasm] (Drosophila melanogaster)
PRC1.4 [nucleoplasm] (Drosophila melanogaster)
PHC1,PHC2,PHC3 [nucleoplasm] (Drosophila melanogaster)
Homologues of PHC3 [nucleoplasm] (Drosophila melanogaster)
PHC3 [nucleoplasm] (Drosophila melanogaster)
PRC1.4 [nucleoplasm] (Drosophila melanogaster)
PHC1,PHC2,PHC3 [nucleoplasm] (Drosophila melanogaster)
Homologues of PHC3 [nucleoplasm] (Drosophila melanogaster)
PHC3 [nucleoplasm] (Drosophila melanogaster)
p-MAPKAPK3 phosphorylates BMI1 (Drosophila melanogaster)
CDKN2A Gene:H3K27Me3-Nucleosome:PRC1.4 [nucleoplasm] (Drosophila melanogaster)
PRC1.4 [nucleoplasm] (Drosophila melanogaster)
PHC1,PHC2,PHC3 [nucleoplasm] (Drosophila melanogaster)
Homologues of PHC3 [nucleoplasm] (Drosophila melanogaster)
PHC3 [nucleoplasm] (Drosophila melanogaster)
p-PRC1.4 complex [nucleoplasm] (Drosophila melanogaster)
PHC1,PHC2,PHC3 [nucleoplasm] (Drosophila melanogaster)
Homologues of PHC3 [nucleoplasm] (Drosophila melanogaster)
PHC3 [nucleoplasm] (Drosophila melanogaster)
Gene expression (Transcription) (Drosophila melanogaster)
RNA Polymerase II Transcription (Drosophila melanogaster)
Generic Transcription Pathway (Drosophila melanogaster)
Transcriptional Regulation by E2F6 (Drosophila melanogaster)
E2F6 binds the PRC1 complex (Drosophila melanogaster)
E2F6:(TFDP1,TFDP2):PRC1 (BMI1,PCGF2:RYBP:RING1:PHC1,PHC3) [nucleoplasm] (Drosophila melanogaster)
PRC1 (BMI1,PCGF2:RYBP:RING1:PHC1,PHC3) [nucleoplasm] (Drosophila melanogaster)
PHC1,PHC3 [nucleoplasm] (Drosophila melanogaster)
Homologues of PHC3 [nucleoplasm] (Drosophila melanogaster)
PHC3 [nucleoplasm] (Drosophila melanogaster)
PRC1 (BMI1,PCGF2:RYBP:RING1:PHC1,PHC3) [nucleoplasm] (Drosophila melanogaster)
PHC1,PHC3 [nucleoplasm] (Drosophila melanogaster)
Homologues of PHC3 [nucleoplasm] (Drosophila melanogaster)
PHC3 [nucleoplasm] (Drosophila melanogaster)
Transcriptional regulation by RUNX1 (Drosophila melanogaster)
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known (Drosophila melanogaster)
RUNX1 binds PRC1 complexes (Drosophila melanogaster)
(PRC1.4,PRC1.5) [nucleoplasm] (Drosophila melanogaster)
PRC1.4 [nucleoplasm] (Drosophila melanogaster)
PHC1,PHC2,PHC3 [nucleoplasm] (Drosophila melanogaster)
Homologues of PHC3 [nucleoplasm] (Drosophila melanogaster)
PHC3 [nucleoplasm] (Drosophila melanogaster)
RUNX1:CBFB:(PRC1.4,PRC1.5) [nucleoplasm] (Drosophila melanogaster)
(PRC1.4,PRC1.5) [nucleoplasm] (Drosophila melanogaster)
PRC1.4 [nucleoplasm] (Drosophila melanogaster)
PHC1,PHC2,PHC3 [nucleoplasm] (Drosophila melanogaster)
Homologues of PHC3 [nucleoplasm] (Drosophila melanogaster)
PHC3 [nucleoplasm] (Drosophila melanogaster)
Metabolism of proteins (Drosophila melanogaster)
Post-translational protein modification (Drosophila melanogaster)
SUMOylation (Drosophila melanogaster)
SUMO E3 ligases SUMOylate target proteins (Drosophila melanogaster)
SUMOylation of DNA damage response and repair proteins (Drosophila melanogaster)
CBX4 (Pc2) SUMOylates CETN2 with SUMO2,3 (Drosophila melanogaster)
PRC1 complex [nucleoplasm] (Drosophila melanogaster)
PHC1,PHC2,PHC3 [nucleoplasm] (Drosophila melanogaster)
Homologues of PHC3 [nucleoplasm] (Drosophila melanogaster)
PHC3 [nucleoplasm] (Drosophila melanogaster)
SUMOylation of RNA binding proteins (Drosophila melanogaster)
CBX4 (Pc2) SUMOylates HNRNPK with SUMO2 (Drosophila melanogaster)
PRC1 complex [nucleoplasm] (Drosophila melanogaster)
PHC1,PHC2,PHC3 [nucleoplasm] (Drosophila melanogaster)
Homologues of PHC3 [nucleoplasm] (Drosophila melanogaster)
PHC3 [nucleoplasm] (Drosophila melanogaster)
SUMOylation of transcription cofactors (Drosophila melanogaster)
PRC1 SUMOylates CTBP1 with SUMO2,3 (Drosophila melanogaster)
PRC1 complex [nucleoplasm] (Drosophila melanogaster)
PHC1,PHC2,PHC3 [nucleoplasm] (Drosophila melanogaster)
Homologues of PHC3 [nucleoplasm] (Drosophila melanogaster)
PHC3 [nucleoplasm] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Intracellular signaling by second messengers (Drosophila melanogaster)
PIP3 activates AKT signaling (Drosophila melanogaster)
PTEN Regulation (Drosophila melanogaster)
Regulation of PTEN gene transcription (Drosophila melanogaster)
MECOM (EVI1) recruits polycomb repressor complexes (PRCs) to the PTEN gene promoter (Drosophila melanogaster)
MECOM:(PRC1.4,PRC2 (EZH2) core):PTEN gene [nucleoplasm] (Drosophila melanogaster)
MECOM:(PRC1.4,PRC2 (EZH2) core) [nucleoplasm] (Drosophila melanogaster)
PRC1.4,PRC2 (EZH2) core [nucleoplasm] (Drosophila melanogaster)
PRC1.4 [nucleoplasm] (Drosophila melanogaster)
PHC1,PHC2,PHC3 [nucleoplasm] (Drosophila melanogaster)
Homologues of PHC3 [nucleoplasm] (Drosophila melanogaster)
PHC3 [nucleoplasm] (Drosophila melanogaster)
PRC1.4,PRC2 (EZH2) core [nucleoplasm] (Drosophila melanogaster)
PRC1.4 [nucleoplasm] (Drosophila melanogaster)
PHC1,PHC2,PHC3 [nucleoplasm] (Drosophila melanogaster)
Homologues of PHC3 [nucleoplasm] (Drosophila melanogaster)
PHC3 [nucleoplasm] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:P39769
Reference Genes
BioGPS Gene:31181
ENSEMBL:FBgn0004861
Flybase:FBgn0004861
KEGG Gene (Drosophila melanogaster):Dmel_CG18412
Monarch:31181
NCBI Gene:31181
Reference Transcript
RefSeq:NM_057523.5
Other Identifiers
144393_at
144394_at
1623441_at
31181
GO:0000070
GO:0000278
GO:0003677
GO:0003682
GO:0005515
GO:0005634
GO:0005694
GO:0005700
GO:0005730
GO:0006325
GO:0006351
GO:0006355
GO:0006357
GO:0007059
GO:0008270
GO:0009948
GO:0021954
GO:0022414
GO:0030154
GO:0030708
GO:0030713
GO:0031507
GO:0032991
GO:0035075
GO:0035102
GO:0035186
GO:0042393
GO:0043226
GO:0043565
GO:0044547
GO:0045892
GO:0046872
GO:0048856
GO:0051087
GO:0140014
Participates
as a member of
Homologues of PHC3 [nucleoplasm] (Drosophila melanogaster)
Other forms of this molecule
PHC2 [nucleoplasm]
Inferred From
PHC3 [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_476871.2
Flybase
FBgn0004861
PRO
P39769
PDB
1KW4
,
1PK1
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9VV77
1
l(3)73Ah [nucleoplasm]
(R-DME-8953572)
0.547
2
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