YKI binds to phosphorylated WTS

Stable Identifier
R-DME-390061
Type
Reaction [binding]
Species
Drosophila melanogaster
Compartment
ReviewStatus
5/5
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The transcriptional factor Yorkie (YKI) via it's two WW domains binds to activated Warts (WTS) kinase. However, it appears that this particular binding has no detectable influence on YKI phosphorylation.
Literature References
PubMed ID Title Journal Year
19733165 Phosphorylation-independent repression of Yorkie in Fat-Hippo signaling

Oh, H, Irvine, KD, Reddy, BV

Dev Biol 2009
16096061 The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP

Wu, S, Pan, D, Matthews, K, Barrera, J, Huang, J

Cell 2005
19330023 In vivo analysis of Yorkie phosphorylation sites

Oh, H, Irvine, KD

Oncogene 2009
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