Reactome | phospho-p-S144,T423-PAK1 [cytosol]

phospho-p-S144,T423-PAK1 [cytosol]

Stable Identifier

R-DME-399819

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

cytosol

Synonyms

Q9VI13

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9VI13 Pak

Gene Names

Pak, DPAK, Dpak1, CG10295

Chain

chain:1-704

Reference Genes

BioGPS Gene:44039 Pak

CTD Gene:44039 Pak

KEGG:dme:Dmel_CG10295 Pak

Monarch:44039 Pak

NCBI Gene:44039 Pak

UCSC:Q9VI13 Pak

Reference Transcript

Other Identifiers

153976_at

1634405_s_at

44039

GO:0003824

GO:0004672

GO:0004674

GO:0005515

GO:0005524

GO:0005737

GO:0005829

GO:0005856

GO:0005884

GO:0005925

GO:0006468

GO:0007155

GO:0007391

GO:0007395

GO:0007411

GO:0007480

GO:0012501

GO:0016301

GO:0016328

GO:0016740

GO:0017124

GO:0019991

GO:0030424

GO:0030426

GO:0031252

GO:0031267

GO:0031594

GO:0034330

GO:0035072

GO:0035075

GO:0035556

GO:0042995

GO:0043067

GO:0043226

GO:0043408

GO:0045887

GO:0048102

GO:0048870

GO:0050770

GO:0050803

GO:0070161

GO:0090128

GO:0097482

GO:0098696

GO:0140096

Participates

as a component of

as an output of

as an input of

FLNA binds PAK1 (Drosophila melanogaster)

as a member of

Other forms of this molecule

phospho-p-S141,T402-PAK2 [cytosol]

PAK2 [cytosol]

PAK1 [cytosol]

PAK3 [cytosol]

phospho-p-S154,T436-PAK3 [cytosol]

phospho-p-Y130,S141,T402-PAK2 [cytosol]

Pak [cytosol]

phospho-p-S141,T402-PAK2 [plasma membrane]

phospho-p-S144,T423-PAK1 [plasma membrane]

phospho-p-S154,T436-PAK3 [plasma membrane]

PAK1 [plasma membrane]

Inferred From

p-S144,T423-PAK1 [cytosol] (Homo sapiens)

Modified Residues

Name

O-phospho-L-serine at 144 (in Homo sapiens)

Coordinate

144

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Name

O-phospho-L-threonine at 423 (in Homo sapiens)

Coordinate

423

PsiMod Name

O-phospho-L-threonine [MOD:00047]

PsiMod Definition

A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.

Cross References

RefSeq

NP_731073.1, NP_001262309.1, NP_731074.1, NP_524681.1, NP_001262313.1

ENSEMBL

FBpp0081212, FBpp0081211, FBtr0081716, FBpp0306606, FBpp0306611, FBtr0081715, FBtr0334544, FBpp0081213, FBtr0334539, FBtr0081714

FlyBase

FBgn0267698

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P40792 Rac1	12	RAC2 [mitochondrial outer membrane] (R-DME-9714496) RAC1 [endoplasmic reticulum membrane] (R-DME-5672076) RHOG [endoplasmic reticulum membrane] (R-DME-5672084) RAC2 [phagocytic vesicle membrane] (R-DME-5668620) RAC1 [secretory granule membrane] (R-DME-6804770) RHOG [secretory granule membrane] (R-DME-6804965) RAC1 [ficolin-1-rich granule membrane] (R-DME-6804802) GGC-PalmC-RAC1 [plasma membrane] (R-DME-2316446) RHOG [cytosol] (R-DME-194909) RAC1_DROME [cytosol] (R-DME-428467) RHOG [plasma membrane] (R-DME-194880) RAC1 [plasma membrane] (R-DME-351103)	0.766	5
UniProt:Q8IPW2 dock	1	DOCK [cytosol] (R-DME-179477)	0.635	3
UniProt:P48554	9	RAC2 [endoplasmic reticulum membrane] (R-DME-9714482) RAC2 [mitochondrial outer membrane] (R-DME-9714496-2) RHOG [endoplasmic reticulum membrane] (R-DME-5672084-2) RAC2 [phagocytic vesicle membrane] (R-DME-5668620-2) RHOG [secretory granule membrane] (R-DME-6804965-2) RAC2 [cytosol] (R-DME-195343) RHOG [cytosol] (R-DME-194909-2) RHOG [plasma membrane] (R-DME-194880-2) RAC2 [plasma membrane] (R-DME-195339)	0.632	3
UniProt:O44924 robo	1	Robo1_DROME [plasma membrane] (R-DME-428452)	0.482	5

Cite Us!