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About
What is Reactome ?
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krz [cytosol]
Stable Identifier
R-DME-416464
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
ARRB2, Q9V393
Locations in the PathwayBrowser
Expand all
Hemostasis (Drosophila melanogaster)
Platelet activation, signaling and aggregation (Drosophila melanogaster)
Thrombin signalling through proteinase activated receptors (PARs) (Drosophila melanogaster)
SRC-1 bound to ARRB2 is not activated (Drosophila melanogaster)
F2R:ARRB2:MAPKs:SRC-1 [plasma membrane] (Drosophila melanogaster)
F2R:ARRB2 [plasma membrane] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
Metabolism of proteins (Drosophila melanogaster)
Post-translational protein modification (Drosophila melanogaster)
Deubiquitination (Drosophila melanogaster)
Ub-specific processing proteases (Drosophila melanogaster)
USP33 deubiquitinates CCP110,ARRB (Drosophila melanogaster)
USP33:CCP110,ARRB1,ARRB2 [cytosol] (Drosophila melanogaster)
CCP110,ARRB2,(ARRB1) [cytosol] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
MAPK family signaling cascades (Drosophila melanogaster)
MAPK1/MAPK3 signaling (Drosophila melanogaster)
RAF/MAP kinase cascade (Drosophila melanogaster)
MAP2K and MAPK activation (Drosophila melanogaster)
Dissociation of RAS:RAF complex (Drosophila melanogaster)
RAF/MAPK scaffolds [cytosol] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Drosophila melanogaster)
RAF/MAPK scaffolds [cytosol] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
Dual mechanism MAP2K inhibitors bind MAP2Ks (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
RAF/MAPK scaffolds [cytosol] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
RAF/MAPK scaffolds [cytosol] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
Dual mechanism MAPK inhibitors bind MAPKs (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
RAF/MAPK scaffolds [cytosol] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
RAF/MAPK scaffolds [cytosol] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
MAP2Ks and MAPKs bind to the activated RAF complex (Drosophila melanogaster)
RAF/MAPK scaffolds [cytosol] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
RAF/MAPK scaffolds [cytosol] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
MAP2Ks phosphorylate MAPKs (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
RAF/MAPK scaffolds [cytosol] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
RAF/MAPK scaffolds [cytosol] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
RAF/MAPK scaffolds [cytosol] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
RAF/MAPK scaffolds [cytosol] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Drosophila melanogaster)
RAF/MAPK scaffolds [cytosol] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
RAF phosphorylates MAP2K dimer (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
RAF/MAPK scaffolds [cytosol] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
RAF/MAPK scaffolds [cytosol] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
RAF/MAPK scaffolds [cytosol] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
RAF/MAPK scaffolds [cytosol] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
RAF/MAPK scaffolds [cytosol] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
Single mechanism MAPK inhibitors bind phosphorylated MAPK (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Drosophila melanogaster)
RAF/MAPK scaffolds [cytosol] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Drosophila melanogaster)
RAF/MAPK scaffolds [cytosol] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
Signaling by GPCR (Drosophila melanogaster)
GPCR downstream signalling (Drosophila melanogaster)
G alpha (s) signalling events (Drosophila melanogaster)
ADRB2:Catecholamine binds ARRB1, ARRB2 (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
pS-ADRB2:Catecholamine:ARRB1,ARRB2 [plasma membrane] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
Signaling by WNT (Drosophila melanogaster)
Beta-catenin independent WNT signaling (Drosophila melanogaster)
PCP/CE pathway (Drosophila melanogaster)
WNT5A-dependent internalization of FZD4 (Drosophila melanogaster)
WNT5A:FZD4 is endocytosed (Drosophila melanogaster)
WNT5A:FZD4:p-DVL2:ARRB2:AP-2:clathrin [plasma membrane] (Drosophila melanogaster)
WNT5A:FZD4:p-DVL2:ARRB2 [plasma membrane] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
Vesicle-mediated transport (Drosophila melanogaster)
Membrane Trafficking (Drosophila melanogaster)
Clathrin-mediated endocytosis (Drosophila melanogaster)
Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
BAR domain proteins recruit dynamin (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
Cargo recognition for clathrin-mediated endocytosis (Drosophila melanogaster)
ARBB recruits GPCRs into clathrin-coated pits (Drosophila melanogaster)
ARBBs:ARBB-binding GPCRs:clathrin-coated pit [plasma membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
ARRB bind GPCRs (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
Clathrin recruits PIK3C2A (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
Dynamin-mediated GTP hydrolysis promotes vesicle scission (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
Endophilins recruit synaptojanins to the clathrin-coated pit (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
F- and N- BAR domain proteins bind the clathrin-coated pit (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
RAB5 and GAPVD1 bind AP-2 (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
ARRB:ARRB-binding GPCRs [plasma membrane] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
krz [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9V393 krz
Gene Names
krz, CG1487, Dmel_CG1487
Reference Genes
BioGPS Gene:53554 krz
KEGG Gene (Drosophila melanogaster):Dmel_CG1487 krz
Monarch:53554 krz
NCBI Gene:53554 krz
UCSC:Q9V393 krz
Reference Transcript
RefSeq:NM_001260471.2 krz
RefSeq:NM_080249.5 krz
Other Identifiers
150964_at
1623793_at
53554
GO:0001664
GO:0002031
GO:0005515
GO:0005737
GO:0005829
GO:0006954
GO:0007165
GO:0016192
GO:0023052
GO:0031648
GO:0035641
GO:0036211
GO:0043409
GO:0045746
GO:0045751
GO:0045879
GO:0048260
GO:0050728
GO:0050896
GO:0060189
GO:0120177
Participates
as a member of
CCP110,ARRB2,(ARRB1) [cytosol] (Drosophila melanogaster)
ARRB [cytosol] (Drosophila melanogaster)
as a component of
F2R:ARRB2 [plasma membrane] (Drosophila melanogaster)
WNT5A:FZD4:p-DVL2:ARRB2 [plasma membrane] (Drosophila melanogaster)
as an output of
WNT5A:FZD4 is endocytosed (Drosophila melanogaster)
as a candidate of
RAF/MAPK scaffolds [cytosol] (Drosophila melanogaster)
Other forms of this molecule
krz [cytoplasmic vesicle membrane]
krz [Golgi membrane]
krz [lysosomal membrane]
krz [cytosol]
krz [cytosol]
Krz [cytosol]
krz [cytosol]
Inferred From
ARRB2 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_524988.1
,
NP_001247400.1
Flybase
FBgn0040206
PRO
Q9V393
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q03017 cact
6
CACT [cytosol]
(R-DME-205871)
Phospho CACT [cytosol]
(R-DME-205886)
cact [nucleoplasm]
(R-DME-4656929)
phospho-cact [cytosol]
(R-DME-1168581)
phospho-cact [cytosol]
(R-DME-177677)
cact [cytosol]
(R-DME-168151)
0.544
2
UniProt:P40417
14
phospho-p-T185,Y187-MAPK1 [nucleoplasm]
(R-DME-112354)
phospho-p-T202,Y204-MAPK3 [nucleoplasm]
(R-DME-112359)
phospho-p-T202,Y204-MAPK3 [cytosol]
(R-DME-109842)
phospho-p-T185,Y187-MAPK1 [cytosol]
(R-DME-109853)
MAPK1 [cytosol]
(R-DME-59282)
MAPK3 [cytosol]
(R-DME-59284)
MAPK3 [nucleoplasm]
(R-DME-73724)
MAPK1 [nucleoplasm]
(R-DME-199960)
phospho-p-T185-MAPK1 [cytosol]
(R-DME-9635773)
phospho-p-T202-MAPK3 [cytosol]
(R-DME-9635775)
phospho-p-Y204-MAPK3-3 [cytosol]
(R-DME-2422448)
MAPK1 [ficolin-1-rich granule lumen]
(R-DME-6800964)
MAPK1 [extracellular region]
(R-DME-6806250)
MAPK1 [azurophil granule lumen]
(R-DME-6799225)
0.544
12
UniProt:Q8SYH8 Q8SYH8
0.488
2
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