Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
His3.3A [nucleoplasm]
Stable Identifier
R-DME-427324
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
nucleoplasm
Synonyms
Me2K-10-H3F3A, C0HL66
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Drosophila melanogaster)
Cellular responses to stress (Drosophila melanogaster)
Cellular Senescence (Drosophila melanogaster)
Senescence-Associated Secretory Phenotype (SASP) (Drosophila melanogaster)
EHMT1:EHMT2 methylates IL6 promoter (Drosophila melanogaster)
IL6 gene:Nucleosome-H3K9Me2 [nucleoplasm] (Drosophila melanogaster)
Nucleosome with H3K9me2 [nucleoplasm] (Drosophila melanogaster)
Histone H3 dimethylated at lysine-9 [nucleoplasm] (Drosophila melanogaster)
Homologues of Me2K-10-H3F3A [nucleoplasm] (Drosophila melanogaster)
His3.3A [nucleoplasm] (Drosophila melanogaster)
EHMT1:EHMT2 methylates IL8 promoter (Drosophila melanogaster)
IL8 gene:Nucleosome-H3K9Me2 [nucleoplasm] (Drosophila melanogaster)
Nucleosome with H3K9me2 [nucleoplasm] (Drosophila melanogaster)
Histone H3 dimethylated at lysine-9 [nucleoplasm] (Drosophila melanogaster)
Homologues of Me2K-10-H3F3A [nucleoplasm] (Drosophila melanogaster)
His3.3A [nucleoplasm] (Drosophila melanogaster)
Gene expression (Transcription) (Drosophila melanogaster)
Epigenetic regulation of gene expression (Drosophila melanogaster)
Negative epigenetic regulation of rRNA expression (Drosophila melanogaster)
NoRC negatively regulates rRNA expression (Drosophila melanogaster)
MBD2 binds methylcytosine in chromatin (Drosophila melanogaster)
Chromatin (H3K9me2, 5mC):MBD2 [nucleoplasm] (Drosophila melanogaster)
Chromatin with H3K9me2, 5mC [nucleoplasm] (Drosophila melanogaster)
Nucleosome with H3K9me2 [nucleoplasm] (Drosophila melanogaster)
Histone H3 dimethylated at lysine-9 [nucleoplasm] (Drosophila melanogaster)
Homologues of Me2K-10-H3F3A [nucleoplasm] (Drosophila melanogaster)
His3.3A [nucleoplasm] (Drosophila melanogaster)
Chromatin with H3K9me2, 5mC [nucleoplasm] (Drosophila melanogaster)
Nucleosome with H3K9me2 [nucleoplasm] (Drosophila melanogaster)
Histone H3 dimethylated at lysine-9 [nucleoplasm] (Drosophila melanogaster)
Homologues of Me2K-10-H3F3A [nucleoplasm] (Drosophila melanogaster)
His3.3A [nucleoplasm] (Drosophila melanogaster)
SIRT1 negatively regulates rRNA expression (Drosophila melanogaster)
Formation of energy-dependent Nucleolar Silencing Complex (eNoSC) (Drosophila melanogaster)
Chromatin (H3K9me2) [nucleoplasm] (Drosophila melanogaster)
Nucleosome with H3K9me2 [nucleoplasm] (Drosophila melanogaster)
Histone H3 dimethylated at lysine-9 [nucleoplasm] (Drosophila melanogaster)
Homologues of Me2K-10-H3F3A [nucleoplasm] (Drosophila melanogaster)
His3.3A [nucleoplasm] (Drosophila melanogaster)
eNoSC [nucleoplasm] (Drosophila melanogaster)
Chromatin (H3K9me2) [nucleoplasm] (Drosophila melanogaster)
Nucleosome with H3K9me2 [nucleoplasm] (Drosophila melanogaster)
Histone H3 dimethylated at lysine-9 [nucleoplasm] (Drosophila melanogaster)
Homologues of Me2K-10-H3F3A [nucleoplasm] (Drosophila melanogaster)
His3.3A [nucleoplasm] (Drosophila melanogaster)
eNoSC deacetylates histone H3 (Drosophila melanogaster)
eNoSC [nucleoplasm] (Drosophila melanogaster)
Chromatin (H3K9me2) [nucleoplasm] (Drosophila melanogaster)
Nucleosome with H3K9me2 [nucleoplasm] (Drosophila melanogaster)
Histone H3 dimethylated at lysine-9 [nucleoplasm] (Drosophila melanogaster)
Homologues of Me2K-10-H3F3A [nucleoplasm] (Drosophila melanogaster)
His3.3A [nucleoplasm] (Drosophila melanogaster)
eNoSC dimethylates histone H3 at lysine-9 (Drosophila melanogaster)
Chromatin (H3K9me2) [nucleoplasm] (Drosophila melanogaster)
Nucleosome with H3K9me2 [nucleoplasm] (Drosophila melanogaster)
Histone H3 dimethylated at lysine-9 [nucleoplasm] (Drosophila melanogaster)
Homologues of Me2K-10-H3F3A [nucleoplasm] (Drosophila melanogaster)
His3.3A [nucleoplasm] (Drosophila melanogaster)
eNoSC [nucleoplasm] (Drosophila melanogaster)
Chromatin (H3K9me2) [nucleoplasm] (Drosophila melanogaster)
Nucleosome with H3K9me2 [nucleoplasm] (Drosophila melanogaster)
Histone H3 dimethylated at lysine-9 [nucleoplasm] (Drosophila melanogaster)
Homologues of Me2K-10-H3F3A [nucleoplasm] (Drosophila melanogaster)
His3.3A [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase I Transcription (Drosophila melanogaster)
RNA Polymerase I Promoter Clearance (Drosophila melanogaster)
RNA Polymerase I Promoter Escape (Drosophila melanogaster)
Elongation of pre-rRNA transcript (Drosophila melanogaster)
Chromatin (H3K9me2):CBX3 [nucleoplasm] (Drosophila melanogaster)
Chromatin (H3K9me2) [nucleoplasm] (Drosophila melanogaster)
Nucleosome with H3K9me2 [nucleoplasm] (Drosophila melanogaster)
Histone H3 dimethylated at lysine-9 [nucleoplasm] (Drosophila melanogaster)
Homologues of Me2K-10-H3F3A [nucleoplasm] (Drosophila melanogaster)
His3.3A [nucleoplasm] (Drosophila melanogaster)
Hemostasis (Drosophila melanogaster)
Factors involved in megakaryocyte development and platelet production (Drosophila melanogaster)
JMJD1C demethylates H3K9 mono- and di-methylation (Drosophila melanogaster)
Histone H3 mono or di-methylated at K9 [nucleoplasm] (Drosophila melanogaster)
Histone H3 dimethylated at lysine-9 [nucleoplasm] (Drosophila melanogaster)
Homologues of Me2K-10-H3F3A [nucleoplasm] (Drosophila melanogaster)
His3.3A [nucleoplasm] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Signaling by Nuclear Receptors (Drosophila melanogaster)
ESR-mediated signaling (Drosophila melanogaster)
Estrogen-dependent gene expression (Drosophila melanogaster)
KDM1A demethylates H3 on MYC and BCL genes in response to estrogen (Drosophila melanogaster)
MYC gene, BCL2 gene: H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG:KDM1A [nucleoplasm] (Drosophila melanogaster)
MYC gene, BLC2 gene:H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG [nucleoplasm] (Drosophila melanogaster)
Nucleosome with H3K9me2 and HIST1H2AC: [nucleoplasm] (Drosophila melanogaster)
Histone H3 dimethylated at lysine-9 [nucleoplasm] (Drosophila melanogaster)
Homologues of Me2K-10-H3F3A [nucleoplasm] (Drosophila melanogaster)
His3.3A [nucleoplasm] (Drosophila melanogaster)
KDM1A is recruited to MYC and BCL2 genes (Drosophila melanogaster)
MYC gene, BCL2 gene: H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG:KDM1A [nucleoplasm] (Drosophila melanogaster)
MYC gene, BLC2 gene:H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG [nucleoplasm] (Drosophila melanogaster)
Nucleosome with H3K9me2 and HIST1H2AC: [nucleoplasm] (Drosophila melanogaster)
Histone H3 dimethylated at lysine-9 [nucleoplasm] (Drosophila melanogaster)
Homologues of Me2K-10-H3F3A [nucleoplasm] (Drosophila melanogaster)
His3.3A [nucleoplasm] (Drosophila melanogaster)
MYC gene, BLC2 gene:H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG [nucleoplasm] (Drosophila melanogaster)
Nucleosome with H3K9me2 and HIST1H2AC: [nucleoplasm] (Drosophila melanogaster)
Histone H3 dimethylated at lysine-9 [nucleoplasm] (Drosophila melanogaster)
Homologues of Me2K-10-H3F3A [nucleoplasm] (Drosophila melanogaster)
His3.3A [nucleoplasm] (Drosophila melanogaster)
Overexpressed HIST1H2AC and ESR1:ESTG bind MYC and BCL2 genes (Drosophila melanogaster)
MYC gene, BCL2 gene: H3K9me2 nucleosome [nucleoplasm] (Drosophila melanogaster)
Nucleosome with H3K9me2 [nucleoplasm] (Drosophila melanogaster)
Histone H3 dimethylated at lysine-9 [nucleoplasm] (Drosophila melanogaster)
Homologues of Me2K-10-H3F3A [nucleoplasm] (Drosophila melanogaster)
His3.3A [nucleoplasm] (Drosophila melanogaster)
MYC gene, BLC2 gene:H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG [nucleoplasm] (Drosophila melanogaster)
Nucleosome with H3K9me2 and HIST1H2AC: [nucleoplasm] (Drosophila melanogaster)
Histone H3 dimethylated at lysine-9 [nucleoplasm] (Drosophila melanogaster)
Homologues of Me2K-10-H3F3A [nucleoplasm] (Drosophila melanogaster)
His3.3A [nucleoplasm] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:C0HL66
Gene Names
His3.3A
Reference Genes
BioGPS Gene:31848 His3.3A
BioGPS Gene:33736 His3.3A
CTD Gene:31848 His3.3A
ENSEMBL:FBgn0014857
Flybase:FBgn0014857
KEGG Gene (Drosophila melanogaster):Dmel_CG5825 His3.3A
KEGG Gene (Drosophila melanogaster):Dmel_CG8989 His3.3A
Monarch:31848 His3.3A
Monarch:33736 His3.3A
NCBI Gene:31848 His3.3A
NCBI Gene:33736 His3.3A
Reference Transcript
RefSeq:NM_001272445.2 His3.3A
RefSeq:NM_176719.1 His3.3A
RefSeq:NM_167180.4 His3.3A
RefSeq:NM_078755.3 His3.3A
RefSeq:NM_001273153.1 His3.3A
RefSeq:NM_164624.3 His3.3A
RefSeq:NM_078540.5 His3.3A
Other Identifiers
142668_at
143766_i_at
143767_r_at
1623222_s_at
1627685_a_at
31848
33736
GO:0000786
GO:0003677
GO:0005198
GO:0005634
GO:0005694
GO:0005700
GO:0006325
GO:0006334
GO:0030527
GO:0043226
GO:0046982
GO:0065003
Participates
as a member of
Homologues of Me2K-10-H3F3A [nucleoplasm] (Drosophila melanogaster)
Other forms of this molecule
His3.3A [nucleoplasm]
His3.3A [nucleoplasm]
His3.3A [nucleoplasm]
His3.3A [nucleoplasm]
His3.3A [nucleoplasm]
His3.3A [nucleoplasm]
His3.3A [nucleoplasm]
phospho-His3.3A [nucleoplasm]
phospho-His3.3A [nucleoplasm]
His3.3A [nucleoplasm]
phospho-His3.3A [nucleoplasm]
His3.3A [nucleoplasm]
His3.3A [nucleoplasm]
Inferred From
Me2K-10-H3F3A [nucleoplasm]
(Homo sapiens)
Modified Residues
Name
N6,N6-dimethyl-L-lysine at 10 (in Homo sapiens)
Coordinate
10
PsiMod Name
N6,N6-dimethyl-L-lysine [MOD:00084]
PsiMod Definition
A protein modification that effectively converts an L-lysine residue to N6,N6-dimethyl-L-lysine.
Cross References
RefSeq
NP_001260082.1
,
NP_727314.1
,
NP_523479.1
,
NP_001259374.1
,
NP_511095.1
,
NP_788892.1
,
NP_723056.2
Flybase
FBgn0014857
PRO
C0HL66
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text