PP1 dephosphorylates phosphorylated TIM

Stable Identifier
R-DME-432427
Type
Reaction [transition]
Species
Drosophila melanogaster
Compartment
cytosol
ReviewStatus
5/5
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PP1 dephosphorylates phosphorylated TIM
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The protein phosphatase, PP1, dephosphorylates and stabilises Timeless (TIM) which helps promote the accumulation of Period (PER).
Literature References
PubMed ID Title Journal Year
17575052 Post-translational regulation of the Drosophila circadian clock requires protein phosphatase 1 (PP1)

Fang, Y, Sehgal, A, Sathyanarayanan, S

Genes Dev 2007
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Catalyst Activity

protein serine/threonine phosphatase activity of Phospho TIM:PP1 [cytosol]

Physical Entity
Phospho TIM:PP1 [cytosol] (Drosophila melanogaster)
Activity
protein serine/threonine phosphatase activity (GO:0004722)
Authored
Williams, MG  (2009-08-13)
Reviewed
Edery, I  (2010-07-06)
Created
Williams, MG  (2009-08-14)
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