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Nedd8 [cytosol]
Stable Identifier
R-DME-4419895
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
C111-AcM-UBE2M-G76-NEDD8, Q9VJ33
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Drosophila melanogaster)
Post-translational protein modification (Drosophila melanogaster)
Neddylation (Drosophila melanogaster)
AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex (Drosophila melanogaster)
NEDD8-AcM-UBE2M:CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Drosophila melanogaster)
NEDD8-AcM-UBE2M [cytosol] (Drosophila melanogaster)
Nedd8 [cytosol] (Drosophila melanogaster)
AcM-UBE2M transfers NEDD8 to CRL2 E3 ubiquitin ligase complex (Drosophila melanogaster)
NEDD8-AcM-UBE2M:CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Drosophila melanogaster)
NEDD8-AcM-UBE2M [cytosol] (Drosophila melanogaster)
Nedd8 [cytosol] (Drosophila melanogaster)
AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex (Drosophila melanogaster)
NEDD8-AcM-UBE2M:CRL3 E3 ubiquitin ligase :DCUN1D1,2,4,5 [cytosol] (Drosophila melanogaster)
NEDD8-AcM-UBE2M [cytosol] (Drosophila melanogaster)
Nedd8 [cytosol] (Drosophila melanogaster)
NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex (Drosophila melanogaster)
NEDD8-AcM-UBE2M [cytosol] (Drosophila melanogaster)
Nedd8 [cytosol] (Drosophila melanogaster)
NEDD8-AcM-UBE2M:CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Drosophila melanogaster)
NEDD8-AcM-UBE2M [cytosol] (Drosophila melanogaster)
Nedd8 [cytosol] (Drosophila melanogaster)
NEDD8:AcM-UBE2M binds CRL2 E3 ubiquitin ligase complex (Drosophila melanogaster)
NEDD8-AcM-UBE2M [cytosol] (Drosophila melanogaster)
Nedd8 [cytosol] (Drosophila melanogaster)
NEDD8-AcM-UBE2M:CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Drosophila melanogaster)
NEDD8-AcM-UBE2M [cytosol] (Drosophila melanogaster)
Nedd8 [cytosol] (Drosophila melanogaster)
NEDD8:AcM-UBE2M binds CRL3 E3 ubiquitin ligase complex (Drosophila melanogaster)
NEDD8-AcM-UBE2M [cytosol] (Drosophila melanogaster)
Nedd8 [cytosol] (Drosophila melanogaster)
NEDD8-AcM-UBE2M:CRL3 E3 ubiquitin ligase :DCUN1D1,2,4,5 [cytosol] (Drosophila melanogaster)
NEDD8-AcM-UBE2M [cytosol] (Drosophila melanogaster)
Nedd8 [cytosol] (Drosophila melanogaster)
Transfer of NEDD8 to AcM-UBE2M (Drosophila melanogaster)
NEDD8-AcM-UBE2M [cytosol] (Drosophila melanogaster)
Nedd8 [cytosol] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Signaling by TGFB family members (Drosophila melanogaster)
Signaling by TGF-beta Receptor Complex (Drosophila melanogaster)
TGF-beta receptor signaling activates SMADs (Drosophila melanogaster)
CBL neddylates TGFBR2 (Drosophila melanogaster)
NEDD8-AcM-UBE2M [cytosol] (Drosophila melanogaster)
Nedd8 [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9VJ33
Gene Names
Nedd8
Reference Genes
BioGPS Gene:35151 Nedd8
ENSEMBL:FBgn0032725
FlyBase:FBgn0032725
KEGG Gene (Drosophila melanogaster):Dmel_CG10679 Nedd8
Monarch:35151 Nedd8
NCBI Gene:35151 Nedd8
Reference Transcript
RefSeq:NM_001299141.1 Nedd8
RefSeq:NM_136075.3 Nedd8
Other Identifiers
146460_at
1624883_at
35151
GO:0005515
GO:0005634
GO:0005737
GO:0008152
GO:0008283
GO:0008589
GO:0019941
GO:0023052
GO:0030154
GO:0030162
GO:0030163
GO:0030431
GO:0031386
GO:0031625
GO:0031647
GO:0036099
GO:0036211
GO:0043226
GO:0045116
GO:0045879
GO:0051438
GO:2000736
Participates
as a component of
NEDD8-AcM-UBE2M [cytosol] (Drosophila melanogaster)
Other forms of this molecule
Nedd8 [nucleoplasm]
Nedd8 [nucleoplasm]
Nedd8 [cytosol]
Nedd8 [cytosol]
Nedd8 [cytosol]
Nedd8 [cytosol]
Nedd8 [cytosol]
Inferred From
C111-AcM-UBE2M-G76-NEDD8 [cytosol]
(Homo sapiens)
Modified Residues
Name
Inter-chain Crosslink via S-(glycyl)-L-cysteine (Cys-Gly) at 76 and 111 (in Homo sapiens)
Coordinate
76
PsiMod Name
S-(glycyl)-L-cysteine (Cys-Gly)
PsiMod Definition
A protein modification that effectively crosslinks an L-cysteine residue and a glycine residue by a thioester bond to form S-glycyl-L-cysteine.
Cross References
RefSeq
NP_001286070.1
,
NP_609919.1
Flybase
FBgn0032725
PRO
Q9VJ33
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