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Su(fu) [cytosol]
Stable Identifier
R-DME-445455
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
SUFU, Q9VG38
Locations in the PathwayBrowser
Expand all
Signal Transduction (Drosophila melanogaster)
Signaling by Hedgehog (Drosophila melanogaster)
Hedgehog 'off' state (Drosophila melanogaster)
Degradation of GLI1 by the proteasome (Drosophila melanogaster)
GLI1 is degraded by the proteasome after ubiquitination by beta-TrCP (Drosophila melanogaster)
Su(fu) [cytosol] (Drosophila melanogaster)
GLI proteins bind SUFU (Drosophila melanogaster)
GLI:SUFU [cytosol] (Drosophila melanogaster)
Su(fu) [cytosol] (Drosophila melanogaster)
Su(fu) [cytosol] (Drosophila melanogaster)
GLI3 is processed to GLI3R by the proteasome (Drosophila melanogaster)
GLI3 is partially degraded by the proteasome to yield the GLI3 repressor (Drosophila melanogaster)
Su(fu) [cytosol] (Drosophila melanogaster)
The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip (Drosophila melanogaster)
GLI:SUFU [cytosol] (Drosophila melanogaster)
Su(fu) [cytosol] (Drosophila melanogaster)
Hedgehog 'on' state (Drosophila melanogaster)
GLI proteins bind SUFU (Drosophila melanogaster)
GLI:SUFU [cytosol] (Drosophila melanogaster)
Su(fu) [cytosol] (Drosophila melanogaster)
Su(fu) [cytosol] (Drosophila melanogaster)
GLI:SUFU translocates to the ciliary tip in response to Hh signaling (Drosophila melanogaster)
GLI:SUFU [cytosol] (Drosophila melanogaster)
Su(fu) [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9VG38
Gene Names
Su(fu)
Reference Genes
BioGPS Gene:41565 Su(fu)
ENSEMBL:FBgn0005355
Flybase:FBgn0005355
KEGG Gene (Drosophila melanogaster):Dmel_CG6054 Su(fu)
Monarch:41565 Su(fu)
NCBI Gene:41565 Su(fu)
UCSC:Q9VG38 Su(fu)
Reference Transcript
RefSeq:NM_080502.5 Su(fu)
Other Identifiers
153324_at
1638427_at
41565
GO:0005515
GO:0005634
GO:0005737
GO:0005829
GO:0006351
GO:0006355
GO:0006913
GO:0008134
GO:0008139
GO:0023052
GO:0032991
GO:0042994
GO:0043226
GO:0043433
GO:0045879
GO:0046823
GO:0051220
GO:0061629
GO:0140297
GO:0140311
GO:0140313
Participates
as an output of
GLI1 is degraded by the proteasome after ubiquitination by beta-TrCP (Drosophila melanogaster)
GLI3 is partially degraded by the proteasome to yield the GLI3 repressor (Drosophila melanogaster)
as an input of
GLI proteins bind SUFU (Drosophila melanogaster)
as a component of
GLI:SUFU [cytosol] (Drosophila melanogaster)
Other forms of this molecule
Su(fu) [ciliary tip]
Su(fu) [ciliary base]
Inferred From
SUFU [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_536750.2
Flybase
FBgn0005355
PDB
4KMA
,
6LPH
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P19538 ci
20
CI [nucleoplasm]
(R-DME-205911)
CI75 [nucleoplasm]
(R-DME-205741)
CI75 [cytosol]
(R-DME-206171)
CI [cytosol]
(R-DME-206046)
Phospho (3 sites) CI [cytosol]
(R-DME-205938)
Phospho (11 sites) CI [cytosol]
(R-DME-205757)
Phospho (13 sites) CI [cytosol]
(R-DME-205801)
Phospho (16 sites) CI [cytosol]
(R-DME-206294)
phospho-ci [nucleoplasm]
(R-DME-5635059)
phospho-ci [nucleoplasm]
(R-DME-5635060)
phospho-ci [ciliary base]
(R-DME-5610514)
ci [nucleoplasm]
(R-DME-5610371)
ci [cytosol]
(R-DME-5610369)
phospho-ci [ciliary base]
(R-DME-5610506)
phospho-ci [ciliary base]
(R-DME-5610485)
phospho-ci [ciliary base]
(R-DME-5610454)
phospho-ci [ciliary base]
(R-DME-5610492)
ci [ciliary base]
(R-DME-5610365)
ci [ciliary tip]
(R-DME-5610367)
ci [ciliary tip]
(R-DME-5610360)
0.764
5
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