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phospho-Pli [cytosol]
Stable Identifier
R-DME-450815
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
p-PELI1, O77237
Locations in the PathwayBrowser
Expand all
Immune System (Drosophila melanogaster)
Cytokine Signaling in Immune system (Drosophila melanogaster)
Signaling by Interleukins (Drosophila melanogaster)
Interleukin-1 family signaling (Drosophila melanogaster)
Interleukin-1 signaling (Drosophila melanogaster)
K63polyUb-IRAK1 dissociates (Drosophila melanogaster)
K63polyUb-hp-IRAK1:p-Pellino-1,2,(3):UBE2N:UBE2V1 [cytosol] (Drosophila melanogaster)
K63polyUb-hp-IRAK1:p-Pellino-1,2,(3) [cytosol] (Drosophila melanogaster)
phospho-Pli [cytosol] (Drosophila melanogaster)
phospho-Pli [cytosol] (Drosophila melanogaster)
Pellino ubiquitinates IRAK1 (Drosophila melanogaster)
K63polyUb-hp-IRAK1:p-Pellino-1,2,(3):UBE2N:UBE2V1 [cytosol] (Drosophila melanogaster)
K63polyUb-hp-IRAK1:p-Pellino-1,2,(3) [cytosol] (Drosophila melanogaster)
phospho-Pli [cytosol] (Drosophila melanogaster)
hp-IRAK1: p-Pellino-1,2,(3):UBE2N:UBE2V1:K63polyUb [cytosol] (Drosophila melanogaster)
hp-IRAK1: p-Pellino-1,2,(3) [cytosol] (Drosophila melanogaster)
phospho-Pli [cytosol] (Drosophila melanogaster)
hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2. (Drosophila melanogaster)
hp-IRAK1:p-Pellino, IRAK4:p-Pellino [cytosol] (Drosophila melanogaster)
IRAK4: p-Pellino-1,2,3 [cytosol] (Drosophila melanogaster)
phospho-Pli [cytosol] (Drosophila melanogaster)
hp-IRAK1: p-Pellino-1,2,(3) [cytosol] (Drosophila melanogaster)
phospho-Pli [cytosol] (Drosophila melanogaster)
hp-IRAK1:p-Pellino, IRAK4:p-Pellino bind UBE2N:UBE2V1 (Drosophila melanogaster)
IRAK1:Pellino:E2 complexes [cytosol] (Drosophila melanogaster)
IRAK4: p-Pellino-1,2,3:UBE2N:UBE2V1:K63polyUb [cytosol] (Drosophila melanogaster)
IRAK4: p-Pellino-1,2,3 [cytosol] (Drosophila melanogaster)
phospho-Pli [cytosol] (Drosophila melanogaster)
hp-IRAK1: p-Pellino-1,2,(3):UBE2N:UBE2V1:K63polyUb [cytosol] (Drosophila melanogaster)
hp-IRAK1: p-Pellino-1,2,(3) [cytosol] (Drosophila melanogaster)
phospho-Pli [cytosol] (Drosophila melanogaster)
hp-IRAK1:p-Pellino, IRAK4:p-Pellino [cytosol] (Drosophila melanogaster)
IRAK4: p-Pellino-1,2,3 [cytosol] (Drosophila melanogaster)
phospho-Pli [cytosol] (Drosophila melanogaster)
hp-IRAK1: p-Pellino-1,2,(3) [cytosol] (Drosophila melanogaster)
phospho-Pli [cytosol] (Drosophila melanogaster)
Innate Immune System (Drosophila melanogaster)
Toll-like Receptor Cascades (Drosophila melanogaster)
Toll Like Receptor 10 (TLR10) Cascade (Drosophila melanogaster)
MyD88 cascade initiated on plasma membrane (Drosophila melanogaster)
IRAK1 recruits IKK complex (Drosophila melanogaster)
IRAK1 phosphorylates Pellino (Drosophila melanogaster)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Drosophila melanogaster)
phospho-Pli [cytosol] (Drosophila melanogaster)
Pellino binds hp-IRAK1:TRAF6 (Drosophila melanogaster)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Drosophila melanogaster)
phospho-Pli [cytosol] (Drosophila melanogaster)
phospho-Pli [cytosol] (Drosophila melanogaster)
Pellino ubiquitinates hp-IRAK1 (Drosophila melanogaster)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Drosophila melanogaster)
phospho-Pli [cytosol] (Drosophila melanogaster)
phospho-Pli [cytosol] (Drosophila melanogaster)
Toll Like Receptor 2 (TLR2) Cascade (Drosophila melanogaster)
Toll Like Receptor TLR1:TLR2 Cascade (Drosophila melanogaster)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Drosophila melanogaster)
IRAK1 recruits IKK complex (Drosophila melanogaster)
IRAK1 phosphorylates Pellino (Drosophila melanogaster)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Drosophila melanogaster)
phospho-Pli [cytosol] (Drosophila melanogaster)
Pellino binds hp-IRAK1:TRAF6 (Drosophila melanogaster)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Drosophila melanogaster)
phospho-Pli [cytosol] (Drosophila melanogaster)
phospho-Pli [cytosol] (Drosophila melanogaster)
Pellino ubiquitinates hp-IRAK1 (Drosophila melanogaster)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Drosophila melanogaster)
phospho-Pli [cytosol] (Drosophila melanogaster)
phospho-Pli [cytosol] (Drosophila melanogaster)
Toll Like Receptor TLR6:TLR2 Cascade (Drosophila melanogaster)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Drosophila melanogaster)
IRAK1 recruits IKK complex (Drosophila melanogaster)
IRAK1 phosphorylates Pellino (Drosophila melanogaster)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Drosophila melanogaster)
phospho-Pli [cytosol] (Drosophila melanogaster)
Pellino binds hp-IRAK1:TRAF6 (Drosophila melanogaster)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Drosophila melanogaster)
phospho-Pli [cytosol] (Drosophila melanogaster)
phospho-Pli [cytosol] (Drosophila melanogaster)
Pellino ubiquitinates hp-IRAK1 (Drosophila melanogaster)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Drosophila melanogaster)
phospho-Pli [cytosol] (Drosophila melanogaster)
phospho-Pli [cytosol] (Drosophila melanogaster)
Toll Like Receptor 4 (TLR4) Cascade (Drosophila melanogaster)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Drosophila melanogaster)
IRAK1 recruits IKK complex (Drosophila melanogaster)
IRAK1 phosphorylates Pellino (Drosophila melanogaster)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Drosophila melanogaster)
phospho-Pli [cytosol] (Drosophila melanogaster)
Pellino binds hp-IRAK1:TRAF6 (Drosophila melanogaster)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Drosophila melanogaster)
phospho-Pli [cytosol] (Drosophila melanogaster)
phospho-Pli [cytosol] (Drosophila melanogaster)
Pellino ubiquitinates hp-IRAK1 (Drosophila melanogaster)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Drosophila melanogaster)
phospho-Pli [cytosol] (Drosophila melanogaster)
phospho-Pli [cytosol] (Drosophila melanogaster)
Toll Like Receptor 5 (TLR5) Cascade (Drosophila melanogaster)
MyD88 cascade initiated on plasma membrane (Drosophila melanogaster)
IRAK1 recruits IKK complex (Drosophila melanogaster)
IRAK1 phosphorylates Pellino (Drosophila melanogaster)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Drosophila melanogaster)
phospho-Pli [cytosol] (Drosophila melanogaster)
Pellino binds hp-IRAK1:TRAF6 (Drosophila melanogaster)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Drosophila melanogaster)
phospho-Pli [cytosol] (Drosophila melanogaster)
phospho-Pli [cytosol] (Drosophila melanogaster)
Pellino ubiquitinates hp-IRAK1 (Drosophila melanogaster)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Drosophila melanogaster)
phospho-Pli [cytosol] (Drosophila melanogaster)
phospho-Pli [cytosol] (Drosophila melanogaster)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Drosophila melanogaster)
MyD88 dependent cascade initiated on endosome (Drosophila melanogaster)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Drosophila melanogaster)
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation (Drosophila melanogaster)
IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation (Drosophila melanogaster)
p-Pellino:hp-IRAK1:TRAF6 [endosome membrane] (Drosophila melanogaster)
phospho-Pli [cytosol] (Drosophila melanogaster)
Pellino binds hp-IRAK1:TRAF6 upon TLR7/8 or 9 activation (Drosophila melanogaster)
p-Pellino:hp-IRAK1:TRAF6 [endosome membrane] (Drosophila melanogaster)
phospho-Pli [cytosol] (Drosophila melanogaster)
phospho-Pli [cytosol] (Drosophila melanogaster)
Pellino ubiquitinates hp-IRAK1 upon TLR7/8 or 9 activation
(Drosophila melanogaster)
p-Pellino:hp-IRAK1:TRAF6 [endosome membrane] (Drosophila melanogaster)
phospho-Pli [cytosol] (Drosophila melanogaster)
phospho-Pli [cytosol] (Drosophila melanogaster)
Toll Like Receptor 9 (TLR9) Cascade (Drosophila melanogaster)
MyD88 dependent cascade initiated on endosome (Drosophila melanogaster)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Drosophila melanogaster)
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation (Drosophila melanogaster)
IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation (Drosophila melanogaster)
p-Pellino:hp-IRAK1:TRAF6 [endosome membrane] (Drosophila melanogaster)
phospho-Pli [cytosol] (Drosophila melanogaster)
Pellino binds hp-IRAK1:TRAF6 upon TLR7/8 or 9 activation (Drosophila melanogaster)
p-Pellino:hp-IRAK1:TRAF6 [endosome membrane] (Drosophila melanogaster)
phospho-Pli [cytosol] (Drosophila melanogaster)
phospho-Pli [cytosol] (Drosophila melanogaster)
Pellino ubiquitinates hp-IRAK1 upon TLR7/8 or 9 activation
(Drosophila melanogaster)
p-Pellino:hp-IRAK1:TRAF6 [endosome membrane] (Drosophila melanogaster)
phospho-Pli [cytosol] (Drosophila melanogaster)
phospho-Pli [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:O77237
Gene Names
Pli
Reference Genes
BioGPS Gene:42821 Pli
CTD Gene:42821 Pli
ENSEMBL:FBgn0025574
Flybase:FBgn0025574
KEGG Gene (Drosophila melanogaster):Dmel_CG5212 Pli
Monarch:42821 Pli
NCBI Gene:42821 Pli
Reference Transcript
RefSeq:NM_079742.4 Pli
RefSeq:NM_001104420.3 Pli
Other Identifiers
154889_at
1626980_at
42821
GO:0000209
GO:0002225
GO:0002376
GO:0003674
GO:0004842
GO:0005515
GO:0005575
GO:0005622
GO:0005737
GO:0005829
GO:0005886
GO:0006464
GO:0006950
GO:0007165
GO:0008063
GO:0008150
GO:0008592
GO:0009898
GO:0019207
GO:0030234
GO:0043549
GO:0045087
GO:0045751
GO:0045752
GO:0061630
GO:0070936
GO:1900425
GO:1905035
Participant Of
output
K63polyUb-IRAK1 dissociates
Pellino ubiquitinates hp-IRAK1 upon TLR7/8 or 9 activation
Pellino ubiquitinates hp-IRAK1
input
Pellino binds hp-IRAK1:TRAF6 upon TLR7/8 or 9 activation
Pellino binds hp-IRAK1:TRAF6
hasComponent
hp-IRAK1: p-Pellino-1,2,(3) [cytosol]
IRAK4: p-Pellino-1,2,3 [cytosol]
K63polyUb-hp-IRAK1:p-Pellino-1,2,(3) [cytosol]
p-Pellino:hp-IRAK1:TRAF6 [endosome membrane]
TRAF6:hp-IRAK1:Pellino [plasma membrane]
Other forms of this molecule
phospho-Pli [cytosol]
phospho-Pli [cytosol]
Pli [cytosol]
Pli [cytosol]
Pli [cytosol]
Inferred From
p-PELI1 [cytosol] (Homo sapiens)
p-Pellino-1,2,(3) [cytosol] (Homo sapiens)
Modified Residues
Name
phosphorylated residue at unknown position
PsiMod Name
phosphorylated residue [MOD:00696]
PsiMod Definition
A protein modification that effectively replaces a hydrogen atom with a phosphate group.
Cross References
RefSeq
NP_001097890.1
,
NP_524466.1
Flybase
FBgn0025574
PRO
O77237
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9W226 Q9W226
0.488
2
UniProt:Q9VUK9 Q9VUK9
0.488
2
UniProt:Q7JXU4 Q7JXU4
0.488
2
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