FT is phosphorylated by DCO

Stable Identifier
R-DME-451856
Type
Reaction [transition]
Species
Drosophila melanogaster
Compartment
cytosol, plasma membrane
ReviewStatus
5/5
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FT is phosphorylated by DCO
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The casein kinase 1 epsilon orthologue, Discs overgrown (DCO) phosphorylates the cytoplasmic part of FT at unknown residues.
Literature References
PubMed ID Title Journal Year
19574458 Processing and phosphorylation of the Fat receptor

Feng, Y, Irvine, KD

Proc Natl Acad Sci U S A 2009
19540118 Phosphorylation of the tumor suppressor fat is regulated by its ligand Dachsous and the kinase discs overgrown

Clayton, L, Arbouzova, NI, Saburi, S, Varelas, X, Silva, E, Wrana, J, Sopko, R, Barrios-Rodiles, M, Shaw, S, Gardano, L, Matakatsu, H, Blair, S, McNeill, H

Curr Biol 2009
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Catalyst Activity

protein serine/threonine kinase activity of DS:FT:DCO [plasma membrane]

Physical Entity
DS:FT:DCO [plasma membrane] (Drosophila melanogaster)
Activity
protein serine/threonine kinase activity (GO:0004674)
Authored
Williams, MG  (2010-01-14)
Reviewed
Irvine, KD  (2009-11-25)
Created
Williams, MG  (2010-01-14)
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