Reactome | lwr [nuclear envelope]

lwr [nuclear envelope]

Stable Identifier

R-DME-4655408

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

nuclear envelope

Synonyms

UBE2I, Q7KNM2

Locations in the PathwayBrowser

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Metabolism of proteins (Drosophila melanogaster)

- Post-translational protein modification (Drosophila melanogaster)
  - SUMOylation (Drosophila melanogaster)
    - SUMO E3 ligases SUMOylate target proteins (Drosophila melanogaster)
      - SUMOylation of DNA replication proteins (Drosophila melanogaster)
        
        RANBP2 SUMOylates CDCA8 (Borealin) and PIAS3 SUMOylates AURKB (Aurora-B) (Drosophila melanogaster)
        
        RANBP2:RANGAP1-SUMO1:UBE2I:Nuclear Pore Complex (NPC) [nuclear envelope] (Drosophila melanogaster)
        
        RANBP2:RANGAP1-SUMO1:UBE2I [nuclear envelope] (Drosophila melanogaster)
        
        lwr [nuclear envelope] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q7KNM2

Gene Names

lwr

Reference Genes

BioGPS Gene:33226 lwr

ENSEMBL:FBgn0010602

Flybase:FBgn0010602

KEGG Gene (Drosophila melanogaster):Dmel_CG3018 lwr

Monarch:33226 lwr

NCBI Gene:33226 lwr

Reference Transcript

Other Identifiers

153243_at

1636282_s_at

33226

GO:0000003

GO:0000166

GO:0000228

GO:0000780

GO:0000940

GO:0002225

GO:0002376

GO:0003674

GO:0005515

GO:0005524

GO:0005575

GO:0005622

GO:0005634

GO:0005694

GO:0006464

GO:0007049

GO:0007059

GO:0007143

GO:0007165

GO:0007391

GO:0008150

GO:0008283

GO:0008354

GO:0009058

GO:0009790

GO:0016321

GO:0016740

GO:0016925

GO:0019899

GO:0030154

GO:0030721

GO:0031072

GO:0032991

GO:0033134

GO:0034641

GO:0035204

GO:0035207

GO:0040011

GO:0042802

GO:0043167

GO:0043226

GO:0045611

GO:0045751

GO:0045880

GO:0048856

GO:0048870

GO:0050821

GO:0051091

GO:0051301

GO:0061656

GO:0071560

GO:1904677

Participant Of

hasComponent

RANBP2:RANGAP1-SUMO1:UBE2I [nuclear envelope]

Other forms of this molecule

lwr [nucleoplasm]

lwr [cytosol]

Inferred From

UBE2I [nuclear envelope] (Homo sapiens)

Cross References

RefSeq

NP_476978.1, NP_001259834.1, NP_722637.1, NP_001259833.1

Flybase

FBgn0010602

Interactors (58)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9N6D8 Q9N6D8			0.621	4
UniProt:P09956 ZEST			0.621	5
UniProt:Q7KNM2	5	lwr [nucleoplasm] (R-DME-3730619) lwr [nucleoplasm] (R-DME-912481) lwr [nucleoplasm] (R-DME-3730629) lwr [cytosol] (R-DME-4655342) lwr [nuclear envelope] (R-DME-4655408)	0.621	3
UniProt:O97102	6	smt3 [nucleoplasm] (R-DME-3730611) smt3 [nucleoplasm] (R-DME-2990830) smt3 [nucleoplasm] (R-DME-2984269) smt3 [nucleoplasm] (R-DME-2990837) smt3 [nucleoplasm] (R-DME-2984281) smt3 [nucleoplasm] (R-DME-3730625)	0.502	2
UniProt:Q9VYG4 Q9VYG4			0.488	2
UniProt:Q9VUK9 Q9VUK9			0.488	2
UniProt:Q8WS79	34	ERR [nucleoplasm] (R-DME-6782984) phospho-ERR [nucleoplasm] (R-DME-9024210) ERR [nucleoplasm] (R-DME-446173) ERR [nucleoplasm] (R-DME-446166) ERR [nucleoplasm] (R-DME-3196175) ERR [nucleoplasm] (R-DME-3196163) ERR [cytosol] (R-DME-9020968) ERR [cytosol] (R-DME-9020970) ERR [nucleoplasm] (R-DME-446168) ERR [nucleoplasm] (R-DME-446165) ERR [cytosol] (R-DME-9020991) ERR [cytosol] (R-DME-9020979) ERR [cytosol] (R-DME-9020974) ERR [plasma membrane] (R-DME-9637787) ERR [plasma membrane] (R-DME-9637786) ERR [plasma membrane] (R-DME-9637788) ERR [plasma membrane] (R-DME-9021053) ERR [plasma membrane] (R-DME-9021059) ERR [plasma membrane] (R-DME-9021057) ERR [cytosol] (R-DME-9632177) ERR [cytosol] (R-DME-5618082) ERR [nucleoplasm] (R-DME-446174) ERR [nucleoplasm] (R-DME-3008952) ERR [nucleoplasm] (R-DME-446159) ERR [cytosol] (R-DME-8948964) ERR [cytosol] (R-DME-5618122) ERR [cytosol] (R-DME-5618118) ERR [nucleoplasm] (R-DME-3008717) ERR [nucleoplasm] (R-DME-3196152) ERR [nucleoplasm] (R-DME-3196155) ERR [nucleoplasm] (R-DME-3196158) ERR [nucleoplasm] (R-DME-3196159) ERR [nucleoplasm] (R-DME-3196167) ERR [nucleoplasm] (R-DME-3196173)	0.488	2
UniProt:Q7JUZ9 Q7JUZ9			0.488	2
UniProt:Q9VW28 Q9VW28			0.488	2
UniProt:Q9W4C1 Q9W4C1			0.488	2
UniProt:Q0E8Q6 Q0E8Q6			0.488	2
UniProt:Q9VH90	2	trbd [cytosol] (R-DME-688989) trbd [cytosol] (R-DME-6781939)	0.488	2
UniProt:A0A0B4LET0 A0A0B4LET0			0.488	2
UniProt:C6SV36 C6SV36			0.488	2
UniProt:Q6NND8 Q6NND8			0.488	2
UniProt:Q9V813	1	Mtap [cytosol] (R-DME-1237091)	0.488	2
UniProt:A1Z7A8 COIL			0.488	2
UniProt:Q94513 Q94513			0.488	2
UniProt:Q9VS36 TO6BL			0.488	2
UniProt:Q9VNJ0	1	dgrn [cytosol] (R-DME-975974)	0.488	4
UniProt:Q9W2P8 Q9W2P8			0.488	2
UniProt:Q9VZV5 CYHR1			0.488	2
UniProt:Q960J9 Q960J9			0.488	2
UniProt:Q9VHF0 Q9VHF0			0.488	2
UniProt:A1A706 A1A706			0.488	2
UniProt:Q9VM37 Q9VM37			0.488	2
UniProt:Q7JWH6 Q7JWH6			0.488	2
UniProt:Q9VFX8 Q9VFX8			0.488	2
UniProt:P48596-3 PU			0.488	2
UniProt:Q5BIG7 Q5BIG7			0.488	2
UniProt:Q9VFP2 rdx	3	rdx [nucleoplasm] (R-DME-5635035) RDX [nucleoplasm] (R-DME-216275) rdx [nucleoplasm] (R-DME-5635036)	0.488	2
UniProt:Q9VBP5 Q9VBP5			0.488	2
UniProt:Q9TW27 Q9TW27			0.488	2
UniProt:Q24533	3	D [nucleoplasm] (R-DME-5627706-4) D [nucleoplasm] (R-DME-5625835-4) D [nucleoplasm] (R-DME-452271-4)	0.488	2
UniProt:Q7JQL2 Q7JQL2			0.488	2
UniProt:Q7KN62-3 TER94			0.488	2
UniProt:Q7JR58	1	Echs1 [mitochondrial matrix] (R-DME-54125)	0.488	2
UniProt:Q6NMX3 Q6NMX3			0.488	2
UniProt:Q9VHC0	2	RnpS1 [cytosol] (R-DME-159256) RnpS1 [nucleoplasm] (R-DME-156778)	0.488	2
UniProt:Q9W4Z6 Q9W4Z6			0.488	2
UniProt:Q9VTT1 Q9VTT1			0.488	2
UniProt:Q9VAF2 Q9VAF2			0.488	2
UniProt:Q9W0N9 Q9W0N9			0.488	2
UniProt:Q7JR80 Q7JR80			0.488	2
UniProt:Q9W0N4 Q9W0N4			0.488	2
UniProt:Q9VVT4 Q9VVT4			0.488	4
UniProt:Q7JWW6 Q7JWW6			0.488	2
UniProt:Q7JN06 Q7JN06			0.488	2
UniProt:Q9VSB8 Q9VSB8			0.488	2
UniProt:Q8IFW4 THIOT			0.488	2
UniProt:Q7JNE1 Q7JNE1			0.488	2
UniProt:Q8T8S2	1	Dmel\CG3788 [cytosol] (R-DME-73556-2)	0.488	2
UniProt:M9MRD4 M9MRD4			0.488	2
UniProt:Q7K3E9 Q7K3E9			0.488	2
UniProt:P20385-2 CF2			0.488	2
UniProt:Q8SXP8 Q8SXP8			0.488	2
UniProt:P51023	4	pnt [nucleoplasm] (R-DME-1629809) pnt [nucleoplasm] (R-DME-1629811) phospho-pnt [nucleoplasm] (R-DME-3132720) phospho-pnt [nucleoplasm] (R-DME-3132735)	0.488	2
UniProt:D5SHR0	1	twz [nucleoplasm] (R-DME-8864339)	0.488	2

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