Reactome | Me2sR4-HIST1H4 [nucleoplasm]

Me2sR4-HIST1H4 [nucleoplasm]

Stable Identifier

R-DME-4754243

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

nucleoplasm

Synonyms

P84040

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P84040

Reference Genes

BioGPS Gene:318846

BioGPS Gene:3771854

BioGPS Gene:3771893

BioGPS Gene:3771908

BioGPS Gene:3771935

BioGPS Gene:3771938

BioGPS Gene:3771941

BioGPS Gene:3771947

BioGPS Gene:3772096

BioGPS Gene:3772113

BioGPS Gene:3772129

BioGPS Gene:3772172

BioGPS Gene:3772211

BioGPS Gene:3772254

BioGPS Gene:3772314

BioGPS Gene:3772317

BioGPS Gene:3772319

BioGPS Gene:3772325

BioGPS Gene:3772509

BioGPS Gene:3772519

BioGPS Gene:3772666

BioGPS Gene:3772708

BioGPS Gene:41773

ENSEMBL:FBgn0001200

Flybase:FBgn0001200

KEGG Gene (Drosophila melanogaster):Dmel_CG31611

KEGG Gene (Drosophila melanogaster):Dmel_CG3379

KEGG Gene (Drosophila melanogaster):Dmel_CG33869

KEGG Gene (Drosophila melanogaster):Dmel_CG33871

KEGG Gene (Drosophila melanogaster):Dmel_CG33873

KEGG Gene (Drosophila melanogaster):Dmel_CG33875

KEGG Gene (Drosophila melanogaster):Dmel_CG33877

KEGG Gene (Drosophila melanogaster):Dmel_CG33879

KEGG Gene (Drosophila melanogaster):Dmel_CG33881

KEGG Gene (Drosophila melanogaster):Dmel_CG33883

KEGG Gene (Drosophila melanogaster):Dmel_CG33885

KEGG Gene (Drosophila melanogaster):Dmel_CG33887

KEGG Gene (Drosophila melanogaster):Dmel_CG33889

KEGG Gene (Drosophila melanogaster):Dmel_CG33891

KEGG Gene (Drosophila melanogaster):Dmel_CG33893

KEGG Gene (Drosophila melanogaster):Dmel_CG33895

KEGG Gene (Drosophila melanogaster):Dmel_CG33897

KEGG Gene (Drosophila melanogaster):Dmel_CG33899

KEGG Gene (Drosophila melanogaster):Dmel_CG33901

KEGG Gene (Drosophila melanogaster):Dmel_CG33903

KEGG Gene (Drosophila melanogaster):Dmel_CG33905

KEGG Gene (Drosophila melanogaster):Dmel_CG33907

KEGG Gene (Drosophila melanogaster):Dmel_CG33909

Monarch:318846

Monarch:3771854

Monarch:3771893

Monarch:3771908

Monarch:3771935

Monarch:3771938

Monarch:3771941

Monarch:3771947

Monarch:3772096

Monarch:3772113

Monarch:3772129

Monarch:3772172

Monarch:3772211

Monarch:3772254

Monarch:3772314

Monarch:3772317

Monarch:3772319

Monarch:3772325

Monarch:3772509

Monarch:3772519

Monarch:3772666

Monarch:3772708

Monarch:41773

NCBI Gene:318846

NCBI Gene:3771854

NCBI Gene:3771893

NCBI Gene:3771908

NCBI Gene:3771935

NCBI Gene:3771938

NCBI Gene:3771941

NCBI Gene:3771947

NCBI Gene:3772096

NCBI Gene:3772113

NCBI Gene:3772129

NCBI Gene:3772172

NCBI Gene:3772211

NCBI Gene:3772254

NCBI Gene:3772314

NCBI Gene:3772317

NCBI Gene:3772319

NCBI Gene:3772325

NCBI Gene:3772509

NCBI Gene:3772519

NCBI Gene:3772666

NCBI Gene:3772708

NCBI Gene:41773

UCSC:P84040

Reference Transcript

Other Identifiers

143733_at

1627419_at

1627631_s_at

1635715_at

2NQB

2PYO

2XYI

3C9C

4QLC

4UUZ

4X23

7227.FBpp0091154

A0A0B4KFZ9

AAF55080.1

AAN11126.1

AAN13612.1

AAN13613.1

AAZ66480.1

AAZ66484.1

AAZ66489.1

AAZ66493.1

AAZ66498.1

AAZ66503.1

AAZ66508.1

AAZ66513.1

AAZ66518.1

AAZ66523.1

AAZ66528.1

AAZ66533.1

AAZ66538.1

AAZ66543.1

AAZ66548.1

AAZ66553.1

AAZ66558.1

AAZ66563.1

AAZ66568.1

AAZ66573.1

AAZ66578.1

AGB95957.1

BT001842

BT015217

CAA32435.1

CAA66067.1

EntrezGene:318846

EntrezGene:3771854

EntrezGene:3771893

EntrezGene:3771908

EntrezGene:3771935

EntrezGene:3771938

EntrezGene:3771941

EntrezGene:3771947

EntrezGene:3772096

EntrezGene:3772113

EntrezGene:3772129

EntrezGene:3772172

EntrezGene:3772211

EntrezGene:3772254

EntrezGene:3772314

EntrezGene:3772317

EntrezGene:3772319

EntrezGene:3772325

EntrezGene:3772509

EntrezGene:3772519

EntrezGene:3772666

EntrezGene:3772708

EntrezGene:41773

FBgn0013981

FBgn0051611

FBgn0053871

FBgn0053873

FBgn0053875

FBgn0053883

FBgn0053885

FBgn0053887

FBgn0053889

FBgn0053891

FBgn0053893

FBgn0053895

FBgn0053897

FBgn0053899

FBgn0053901

FBgn0053903

FBgn0053905

FBgn0053907

FBgn0053909

FBpp0082421

FBpp0082422

FBpp0082423

FBpp0085280

FBpp0091116

FBpp0091118

FBpp0091120

FBpp0091128

FBpp0091130

FBpp0091132

FBpp0091134

FBpp0091136

FBpp0091138

FBpp0091140

FBpp0091142

FBpp0091144

FBpp0091146

FBpp0091148

FBpp0091150

FBpp0091152

FBpp0091154

FBpp0306146

FBtr0082962

FBtr0082963

FBtr0082964

FBtr0085926

FBtr0091875

FBtr0091877

FBtr0091879

FBtr0091887

FBtr0091889

FBtr0091891

FBtr0091893

FBtr0091895

FBtr0091897

FBtr0091899

FBtr0091901

FBtr0091903

FBtr0091905

FBtr0091907

FBtr0091909

FBtr0091911

FBtr0091913

FBtr0334029

GO:0000003

GO:0000228

GO:0000786

GO:0000788

GO:0003674

GO:0003677

GO:0005515

GO:0005575

GO:0005622

GO:0005623

GO:0005634

GO:0005694

GO:0006334

GO:0006352

GO:0007049

GO:0007059

GO:0008150

GO:0009058

GO:0016321

GO:0022607

GO:0032991

GO:0034641

GO:0035059

GO:0042393

GO:0043226

GO:0046982

GO:0051276

GO:0065003

IPR001951

IPR004823

IPR009072

IPR019809

IPR035425

NM_001032113.2

NM_001032117.2

NM_001032122.2

NM_001032126.2

NM_001032131.2

NM_001032136.2

NM_001032141.2

NM_001032146.2

NM_001032151.2

NM_001032156.2

NM_001032161.2

NM_001032166.2

NM_001032171.2

NM_001032176.2

NM_001032181.2

NM_001032186.2

NM_001032191.2

NM_001032196.1

NM_001032201.1

NM_001032206.1

NM_001032211.1

NM_001275647.1

NM_079628.4

NM_165383.3

NM_169592.3

NM_169593.3

NP_001027284.1

NP_001027288.1

NP_001027293.1

NP_001027297.1

NP_001027302.1

NP_001027307.1

NP_001027312.1

NP_001027317.1

NP_001027322.1

NP_001027327.1

NP_001027332.1

NP_001027337.1

NP_001027342.1

NP_001027347.1

NP_001027352.1

NP_001027357.1

NP_001027362.1

NP_001027367.1

NP_001027372.1

NP_001027377.1

NP_001027382.1

NP_001262576.1

NP_524352.1

NP_724344.1

NP_731927.1

NP_731928.1

PF15511

PR00623

SM00417

SM00803

UPI0000000B5E

X97438

Participant Of

hasCandidate

Me2sR4-HIST1H4, MeR4-HIST1H4 [nucleoplasm]

input

JMJD6 demethylates Me2sR4-HIST1H4

Other forms of this molecule

SUMO3-HIST1H4 [nucleoplasm]

AcK5,12-HIST1H4A [nucleoplasm]

AcK13-HIST1H4 [nucleoplasm]

AcK6-HIST1H4 [nucleoplasm]

AcK17-HIST1H4 [nucleoplasm]

AcK9-HIST1H4 [nucleoplasm]

Me2aR4-HIST1H4 [nucleoplasm]

MeR4-HIST1H4 [nucleoplasm]

Me3K21-HIST1H4 [nucleoplasm]

AcK-HIST1H4 [nucleoplasm]

MeK-HIST1H4A [nucleoplasm]

HIST1H4 [nucleoplasm]

Me2K21-HIST1H4 [nucleoplasm]

Inferred From

Me2sR4-HIST1H4 [nucleoplasm] (Homo sapiens)

Modified Residues

Name

symmetric dimethyl-L-arginine at 4 (in Homo sapiens)

Coordinate

PsiMod Name

symmetric dimethyl-L-arginine

PsiMod Definition

A protein modification that effectively converts an L-arginine residue to symmetric dimethylarginine, N(omega),N'(omega)-dimethyl-L-arginine.

Cross References

RefSeq

NP_001027327.1, NP_001027297.1, NP_001027352.1, NP_001027357.1, NP_001027284.1, NP_001027312.1, NP_001027382.1, NP_001027337.1, NP_001027288.1, NP_001027367.1, NP_001027322.1, NP_724344.1, NP_001027347.1, NP_001027332.1, NP_001027362.1, NP_001027307.1, NP_001262576.1, NP_001027377.1, NP_001027293.1, NP_001027342.1, NP_731927.1, NP_524352.1, NP_001027372.1, NP_001027317.1, NP_731928.1, NP_001027302.1

Flybase

FBgn0053909

PRO

P84040

PDB

4QLC, 2PYO, 6DZT, 3C9C, 4X23, 5WCU, 2XYI, 6PWF, 2NQB, 4UUZ, 6PWE

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q92831 KAT2B	1	KAT2B [nucleoplasm] (R-HSA-352430)	0.609	2
UniProt:Q9V6Q2 CID			0.597	3
UniProt:P02299	27	2xAcK-HIST2H3A [nucleoplasm] (R-DME-427525) MeK-HIST2H3A [nucleoplasm] (R-DME-417240) AcK24-HIST2H3A [nucleoplasm] (R-DME-4568747) AcK19-HIST2H3A [nucleoplasm] (R-DME-4568750) AcK15-HIST2H3A [nucleoplasm] (R-DME-4568755) AcK5-HIST2H3A [nucleoplasm] (R-DME-4568752) phospho-AcK9,14-p-S10-HIST2H3A [nucleoplasm] (R-DME-8870892) phospho-AcK14,18,79-p-S10-HIST2H3A [nucleoplasm] (R-DME-8871273) phospho-AcK9,14,18-p-S10,T11-HIST2H3A [nucleoplasm] (R-DME-8871304) phospho-AcK14,18-p-S10,T11-HIST2H3A [nucleoplasm] (R-DME-8871292) phospho-AcK9,14,18,79-p-S10,T11-HIST2H3A [nucleoplasm] (R-DME-8865607) phospho-AcK14,18-p-S10-HIST2H3A [nucleoplasm] (R-DME-8871296) phospho-AcK14,18,79-p-T11-HIST2H3A [nucleoplasm] (R-DME-8871290) phospho-AcK14,18-p-T11-HIST2H3A [nucleoplasm] (R-DME-8871302) phospho-AcK14,18,79-p-S10,T11-HIST2H3A [nucleoplasm] (R-DME-8871289) CENPA [nucleoplasm] (R-DME-606322) phospho-p-T12-HIST2H3A [nucleoplasm] (R-DME-5625871) phospho-p-T12,MeK-HIST2H3A [nucleoplasm] (R-DME-5625857) phospho-p-T12, Me2K-10-HIST2H3A [nucleoplasm] (R-DME-5625792) Me3K-10-HIST2H3A [nucleoplasm] (R-DME-427744) phospho-p-T12, Me3K-10-HIST2H3A [nucleoplasm] (R-DME-5625754) Ack10-HIST2H3A [nucleoplasm] (R-DME-4568924) Me2K-10-HIST2H3A [nucleoplasm] (R-DME-427407) Me3K5-HIST2H3A [nucleoplasm] (R-DME-1214223) HIST2H3A [nucleoplasm] (R-DME-212281) Me3K-28-HIST2H3A [nucleoplasm] (R-DME-212253) Me2K5-HIST2H3A [nucleoplasm] (R-DME-1214225)	0.524	2
UniProt:O94267	1	SUPT16H [nucleoplasm] (R-SPO-112415)	0.499	2
UniProt:Q05825	2	ATP5B [mitochondrial matrix] (R-DME-164576) ATP5B(1-47) [mitochondrial matrix] (R-DME-8986172)	0.462	2
UniProt:Q9VHP0	3	DDX3X [extracellular region] (R-DME-6806507) DDX3X [secretory granule lumen] (R-DME-6801275) DDX3X [ficolin-1-rich granule lumen] (R-DME-6801273)	0.462	2
UniProt:P13607	2	ATP4A [plasma membrane] (R-DME-937309-2) ATP12A [plasma membrane] (R-DME-937303-2)	0.462	2