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phospho-Sk1 [cytosol]
Stable Identifier
R-DME-5218716
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
p-S225-SPHK1, Q9VYY8
Locations in the PathwayBrowser
Expand all
Immune System (Drosophila melanogaster)
Cytokine Signaling in Immune system (Drosophila melanogaster)
Interferon Signaling (Drosophila melanogaster)
Antiviral mechanism by IFN-stimulated genes (Drosophila melanogaster)
PKR-mediated signaling (Drosophila melanogaster)
SPHK1 binds PKR (Drosophila melanogaster)
EIF2AK2:p-SPHK1 [cytosol] (Drosophila melanogaster)
phospho-Sk1 [cytosol] (Drosophila melanogaster)
phospho-Sk1 [cytosol] (Drosophila melanogaster)
p-S225-SPHK1 localizes to cytosol (Drosophila melanogaster)
phospho-Sk1 [cytosol] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by VEGF (Drosophila melanogaster)
VEGFA-VEGFR2 Pathway (Drosophila melanogaster)
VEGFR2 mediated cell proliferation (Drosophila melanogaster)
PKC phosphorylates sphingosine kinase 1 (Drosophila melanogaster)
phospho-Sk1 [cytosol] (Drosophila melanogaster)
p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Drosophila melanogaster)
phospho-Sk1 [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9VYY8
Gene Names
Sk1
Reference Genes
BioGPS Gene:32089 Sk1
CTD Gene:32089 Sk1
ENSEMBL:FBgn0030300
Flybase:FBgn0030300
KEGG Gene (Drosophila melanogaster):Dmel_CG1747 Sk1
Monarch:32089 Sk1
NCBI Gene:32089 Sk1
UCSC:Q9VYY8 Sk1
Reference Transcript
RefSeq:NM_167286.2 Sk1
RefSeq:NM_132489.2 Sk1
Other Identifiers
144876_at
1624404_a_at
32089
GO:0001727
GO:0003824
GO:0003951
GO:0005737
GO:0005829
GO:0005886
GO:0006629
GO:0006665
GO:0016020
GO:0016301
GO:0016310
GO:0016740
GO:0017050
GO:0043226
GO:0043231
GO:0046512
GO:0046872
Participates
as an input of
SPHK1 binds PKR (Drosophila melanogaster)
as an output of
p-S225-SPHK1 localizes to cytosol (Drosophila melanogaster)
PKC phosphorylates sphingosine kinase 1 (Drosophila melanogaster)
as a component of
EIF2AK2:p-SPHK1 [cytosol] (Drosophila melanogaster)
Other forms of this molecule
Sk1 [nucleoplasm]
phospho-Sk1 [nucleoplasm]
Sk1 [cytosol]
Sk1 [cytosol]
Inferred From
p-S225-SPHK1 [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 225 (in Homo sapiens)
Coordinate
225
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
NP_727528.1
,
NP_572717.1
Flybase
FBgn0030300
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