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p-S222,S226 MAP2K2 dimer [cytosol]
Stable Identifier
R-DME-5672701
Type
Complex
Species
Drosophila melanogaster
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Signal Transduction (Drosophila melanogaster)
MAPK family signaling cascades (Drosophila melanogaster)
MAPK1/MAPK3 signaling (Drosophila melanogaster)
RAF/MAP kinase cascade (Drosophila melanogaster)
MAP2K and MAPK activation (Drosophila melanogaster)
Dissociation of RAS:RAF complex (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Drosophila melanogaster)
p-2S MAP2K homo/heterodimers [cytosol] (Drosophila melanogaster)
p-S222,S226 MAP2K2 dimer [cytosol] (Drosophila melanogaster)
p-2S MAP2K homo/heterodimers [cytosol] (Drosophila melanogaster)
p-S222,S226 MAP2K2 dimer [cytosol] (Drosophila melanogaster)
Dual mechanism MAPK inhibitors bind MAPKs (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p-2S MAP2K homo/heterodimers [cytosol] (Drosophila melanogaster)
p-S222,S226 MAP2K2 dimer [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p-2S MAP2K homo/heterodimers [cytosol] (Drosophila melanogaster)
p-S222,S226 MAP2K2 dimer [cytosol] (Drosophila melanogaster)
MAP2Ks and MAPKs are phosphorylated at the endosome membrane (Drosophila melanogaster)
WDR83:LAMTOR2:LAMTOR3:activated RAF:p-2S MAP2K:p-T,Y MAPK complex [endosome membrane] (Drosophila melanogaster)
p-2S MAP2K homo/heterodimers [cytosol] (Drosophila melanogaster)
p-S222,S226 MAP2K2 dimer [cytosol] (Drosophila melanogaster)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Drosophila melanogaster)
IL17RD:p-2S MAP2Ks:MAPKs [Golgi membrane] (Drosophila melanogaster)
p-2S MAP2K homo/heterodimers [cytosol] (Drosophila melanogaster)
p-S222,S226 MAP2K2 dimer [cytosol] (Drosophila melanogaster)
IL17RD:p-2S MAP2Ks:p-T,Y MAPKs [Golgi membrane] (Drosophila melanogaster)
p-2S MAP2K homo/heterodimers [cytosol] (Drosophila melanogaster)
p-S222,S226 MAP2K2 dimer [cytosol] (Drosophila melanogaster)
p-2S MAP2K homo/heterodimers [cytosol] (Drosophila melanogaster)
p-S222,S226 MAP2K2 dimer [cytosol] (Drosophila melanogaster)
MAP2Ks phosphorylate MAPKs (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p-2S MAP2K homo/heterodimers [cytosol] (Drosophila melanogaster)
p-S222,S226 MAP2K2 dimer [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p-2S MAP2K homo/heterodimers [cytosol] (Drosophila melanogaster)
p-S222,S226 MAP2K2 dimer [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p-2S MAP2K homo/heterodimers [cytosol] (Drosophila melanogaster)
p-S222,S226 MAP2K2 dimer [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Drosophila melanogaster)
p-2S MAP2K homo/heterodimers [cytosol] (Drosophila melanogaster)
p-S222,S226 MAP2K2 dimer [cytosol] (Drosophila melanogaster)
p-2S MAP2K homo/heterodimers [cytosol] (Drosophila melanogaster)
p-S222,S226 MAP2K2 dimer [cytosol] (Drosophila melanogaster)
RAF phosphorylates MAP2K dimer (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p-2S MAP2K homo/heterodimers [cytosol] (Drosophila melanogaster)
p-S222,S226 MAP2K2 dimer [cytosol] (Drosophila melanogaster)
Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p-2S MAP2K homo/heterodimers [cytosol] (Drosophila melanogaster)
p-S222,S226 MAP2K2 dimer [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p-2S MAP2K homo/heterodimers [cytosol] (Drosophila melanogaster)
p-S222,S226 MAP2K2 dimer [cytosol] (Drosophila melanogaster)
Single mechanism MAPK inhibitors bind phosphorylated MAPK (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Drosophila melanogaster)
p-2S MAP2K homo/heterodimers [cytosol] (Drosophila melanogaster)
p-S222,S226 MAP2K2 dimer [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Drosophila melanogaster)
p-2S MAP2K homo/heterodimers [cytosol] (Drosophila melanogaster)
p-S222,S226 MAP2K2 dimer [cytosol] (Drosophila melanogaster)
RAF activation (Drosophila melanogaster)
Phosphorylation of RAF (Drosophila melanogaster)
RAF activating kinases [plasma membrane] (Drosophila melanogaster)
p-2S MAP2K homo/heterodimers [cytosol] (Drosophila melanogaster)
p-S222,S226 MAP2K2 dimer [cytosol] (Drosophila melanogaster)
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by NTRKs (Drosophila melanogaster)
Signaling by NTRK1 (TRKA) (Drosophila melanogaster)
Signalling to ERKs (Drosophila melanogaster)
Prolonged ERK activation events (Drosophila melanogaster)
Frs2-mediated activation (Drosophila melanogaster)
Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF (Drosophila melanogaster)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:MAPK complex [endosome membrane] (Drosophila melanogaster)
p-2S MAP2K homo/heterodimers [cytosol] (Drosophila melanogaster)
p-S222,S226 MAP2K2 dimer [cytosol] (Drosophila melanogaster)
Dissociation of phosphorylated MAP2Ks and MAPKs (Drosophila melanogaster)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:p-T,Y MAPK complex [endosome membrane] (Drosophila melanogaster)
p-2S MAP2K homo/heterodimers [cytosol] (Drosophila melanogaster)
p-S222,S226 MAP2K2 dimer [cytosol] (Drosophila melanogaster)
p-2S MAP2K homo/heterodimers [cytosol] (Drosophila melanogaster)
p-S222,S226 MAP2K2 dimer [cytosol] (Drosophila melanogaster)
MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF (Drosophila melanogaster)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:MAPK complex [endosome membrane] (Drosophila melanogaster)
p-2S MAP2K homo/heterodimers [cytosol] (Drosophila melanogaster)
p-S222,S226 MAP2K2 dimer [cytosol] (Drosophila melanogaster)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:p-T,Y MAPK complex [endosome membrane] (Drosophila melanogaster)
p-2S MAP2K homo/heterodimers [cytosol] (Drosophila melanogaster)
p-S222,S226 MAP2K2 dimer [cytosol] (Drosophila melanogaster)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
x 2
phospho-p-S222,S226-MAP2K2 [cytosol]
(Drosophila melanogaster)
Participates
as a member of
p-2S MAP2K homo/heterodimers [cytosol] (Drosophila melanogaster)
Inferred From
p-S222,S226 MAP2K2 dimer [cytosol]
(Homo sapiens)
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