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p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane]
Stable Identifier
R-DME-5675414
Type
Complex
Species
Drosophila melanogaster
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Drosophila melanogaster)
MAPK family signaling cascades (Drosophila melanogaster)
MAPK1/MAPK3 signaling (Drosophila melanogaster)
RAF/MAP kinase cascade (Drosophila melanogaster)
MAP2K and MAPK activation (Drosophila melanogaster)
MAP2Ks and MAPKs bind to the activated RAF complex (Drosophila melanogaster)
p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane] (Drosophila melanogaster)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Drosophila melanogaster)
Negative regulation of MAPK pathway (Drosophila melanogaster)
PEBP1 binds activated RAF1 (Drosophila melanogaster)
p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane] (Drosophila melanogaster)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Drosophila melanogaster)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Drosophila melanogaster)
PP5 dephosphorylates RAF1 S338 (Drosophila melanogaster)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Drosophila melanogaster)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
'activator' RAFs [cytosol]
(Drosophila melanogaster)
p21 RAS:GTP [plasma membrane]
(Drosophila melanogaster)
phospho-p-S338,Y341,T491,S494,S621 RAF1 [plasma membrane]
(Drosophila melanogaster)
YWHAB dimer [cytosol]
(Drosophila melanogaster)
Participates
as an input of
PP5 dephosphorylates RAF1 S338 (Drosophila melanogaster)
PEBP1 binds activated RAF1 (Drosophila melanogaster)
as a component of
p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane] (Drosophila melanogaster)
Inferred From
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane]
(Homo sapiens)
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