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PLCB3 [cytosol]
Stable Identifier
R-DME-61747
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
P25455
Locations in the PathwayBrowser
Expand all
Metabolism (Drosophila melanogaster)
Inositol phosphate metabolism (Drosophila melanogaster)
Synthesis of IP3 and IP4 in the cytosol (Drosophila melanogaster)
PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane (Drosophila melanogaster)
PLCbz [cytosol] (Drosophila melanogaster)
PLCB3:Ca2+ [cytosol] (Drosophila melanogaster)
PLCB3 [cytosol] (Drosophila melanogaster)
Integration of energy metabolism (Drosophila melanogaster)
Regulation of insulin secretion (Drosophila melanogaster)
Acetylcholine regulates insulin secretion (Drosophila melanogaster)
Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate (Drosophila melanogaster)
PLC beta1,2,3 [cytosol] (Drosophila melanogaster)
PLCB3 [cytosol] (Drosophila melanogaster)
PLC beta1,2,3:G-alpha(q):GTP [plasma membrane] (Drosophila melanogaster)
PLC beta1,2,3 [cytosol] (Drosophila melanogaster)
PLCB3 [cytosol] (Drosophila melanogaster)
Free fatty acids regulate insulin secretion (Drosophila melanogaster)
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion (Drosophila melanogaster)
Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate (Drosophila melanogaster)
PLC beta1,2,3 [cytosol] (Drosophila melanogaster)
PLCB3 [cytosol] (Drosophila melanogaster)
PLC beta1,2,3:G-alpha(q):GTP [plasma membrane] (Drosophila melanogaster)
PLC beta1,2,3 [cytosol] (Drosophila melanogaster)
PLCB3 [cytosol] (Drosophila melanogaster)
Neuronal System (Drosophila melanogaster)
Transmission across Chemical Synapses (Drosophila melanogaster)
Neurotransmitter receptors and postsynaptic signal transmission (Drosophila melanogaster)
Activation of kainate receptors upon glutamate binding (Drosophila melanogaster)
Presynaptic function of Kainate receptors (Drosophila melanogaster)
Activation of GRIK3 homomer (Drosophila melanogaster)
G-protein beta-gamma:PLC beta 1/2/3 [plasma membrane] (Drosophila melanogaster)
PLC-beta 1/2/3 [cytosol] (Drosophila melanogaster)
PLCB3 [cytosol] (Drosophila melanogaster)
Kainate receptor-glutamate-Gprotein complex [plasma membrane] (Drosophila melanogaster)
G-protein beta-gamma:PLC beta 1/2/3 [plasma membrane] (Drosophila melanogaster)
PLC-beta 1/2/3 [cytosol] (Drosophila melanogaster)
PLCB3 [cytosol] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Signaling by GPCR (Drosophila melanogaster)
GPCR downstream signalling (Drosophila melanogaster)
G alpha (i) signalling events (Drosophila melanogaster)
Opioid Signalling (Drosophila melanogaster)
G-protein mediated events (Drosophila melanogaster)
PLC beta mediated events (Drosophila melanogaster)
Inactivation of PLC beta (Drosophila melanogaster)
Activated PLC beta 1/4 [plasma membrane] (Drosophila melanogaster)
PLC-beta [cytosol] (Drosophila melanogaster)
PLCB3 [cytosol] (Drosophila melanogaster)
PLC-beta [cytosol] (Drosophila melanogaster)
PLCB3 [cytosol] (Drosophila melanogaster)
PIP2 hydrolysis (Drosophila melanogaster)
Activated PLC beta 1/4 [plasma membrane] (Drosophila melanogaster)
PLC-beta [cytosol] (Drosophila melanogaster)
PLCB3 [cytosol] (Drosophila melanogaster)
G alpha (q) signalling events (Drosophila melanogaster)
PLC-beta hydrolyses PIP2 to DAG and IP3 (Drosophila melanogaster)
Activated PLC beta 1/4 [plasma membrane] (Drosophila melanogaster)
PLC-beta [cytosol] (Drosophila melanogaster)
PLCB3 [cytosol] (Drosophila melanogaster)
PLC-beta [cytosol] (Drosophila melanogaster)
PLCB3 [cytosol] (Drosophila melanogaster)
PLC-beta:G-alpha(q/11):DAG:IP3 [plasma membrane] (Drosophila melanogaster)
Activated PLC beta 1/4 [plasma membrane] (Drosophila melanogaster)
PLC-beta [cytosol] (Drosophila melanogaster)
PLCB3 [cytosol] (Drosophila melanogaster)
PLC-beta:G-alpha(q/11):PIP2 [plasma membrane] (Drosophila melanogaster)
Activated PLC beta 1/4 [plasma membrane] (Drosophila melanogaster)
PLC-beta [cytosol] (Drosophila melanogaster)
PLCB3 [cytosol] (Drosophila melanogaster)
G-protein beta:gamma signalling (Drosophila melanogaster)
G beta:gamma signalling through PLC beta (Drosophila melanogaster)
Gbeta:gamma activation of PLC beta (Drosophila melanogaster)
G-protein beta-gamma:PLC beta 1/2/3 [plasma membrane] (Drosophila melanogaster)
PLC-beta 1/2/3 [cytosol] (Drosophila melanogaster)
PLCB3 [cytosol] (Drosophila melanogaster)
PLC-beta 1/2/3 [cytosol] (Drosophila melanogaster)
PLCB3 [cytosol] (Drosophila melanogaster)
PLC beta-mediated PIP2 hydrolysis (Drosophila melanogaster)
G-protein beta-gamma:PLC beta 1/2/3 [plasma membrane] (Drosophila melanogaster)
PLC-beta 1/2/3 [cytosol] (Drosophila melanogaster)
PLCB3 [cytosol] (Drosophila melanogaster)
Signaling by WNT (Drosophila melanogaster)
Beta-catenin independent WNT signaling (Drosophila melanogaster)
Ca2+ pathway (Drosophila melanogaster)
Gbeta:gamma activation of PLC beta (Drosophila melanogaster)
G-protein beta-gamma:PLC beta 1/2/3 [plasma membrane] (Drosophila melanogaster)
PLC-beta 1/2/3 [cytosol] (Drosophila melanogaster)
PLCB3 [cytosol] (Drosophila melanogaster)
PLC-beta 1/2/3 [cytosol] (Drosophila melanogaster)
PLCB3 [cytosol] (Drosophila melanogaster)
PLC beta-mediated PIP2 hydrolysis (Drosophila melanogaster)
G-protein beta-gamma:PLC beta 1/2/3 [plasma membrane] (Drosophila melanogaster)
PLC-beta 1/2/3 [cytosol] (Drosophila melanogaster)
PLCB3 [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:P25455
Reference Genes
BioGPS Gene:33204
ENSEMBL:FBgn0004611
Flybase:FBgn0004611
KEGG Gene (Drosophila melanogaster):Dmel_CG4574
Monarch:33204
NCBI Gene:33204
Reference Transcript
RefSeq:NM_205883.2
RefSeq:NM_057504.5
RefSeq:NM_205884.3
RefSeq:NM_057503.5
RefSeq:NM_205882.2
RefSeq:NM_001272889.1
Other Identifiers
153733_at
1630007_s_at
33204
GO:0003824
GO:0004435
GO:0005509
GO:0006629
GO:0007165
GO:0007629
GO:0008081
GO:0016042
GO:0016787
GO:0023052
GO:0035556
GO:0043153
GO:0048015
GO:0051209
GO:0055065
GO:0055085
GO:0070050
GO:1900073
Participates
as a candidate of
PLC beta1,2,3 [cytosol] (Drosophila melanogaster)
as a member of
PLC-beta 1/2/3 [cytosol] (Drosophila melanogaster)
PLC-beta [cytosol] (Drosophila melanogaster)
as a component of
PLCB3:Ca2+ [cytosol] (Drosophila melanogaster)
Other forms of this molecule
PLCB1 [cytosol]
PLCB2 [cytosol]
Inferred From
PLCB3 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001259818.1
,
NP_476852.1
,
NP_995604.2
,
NP_995605.1
,
NP_995606.1
,
NP_476851.2
Flybase
FBgn0004611
IntEnz
3.1.4.11
PRO
P25455
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