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NDUFS8 [mitochondrial matrix]
Stable Identifier
R-DME-6788526
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
mitochondrial matrix
Synonyms
Q9VF27
Locations in the PathwayBrowser
Expand all
Metabolism (Drosophila melanogaster)
Aerobic respiration and respiratory electron transport (Drosophila melanogaster)
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. (Drosophila melanogaster)
Respiratory electron transport (Drosophila melanogaster)
Complex I biogenesis (Drosophila melanogaster)
IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 (Drosophila melanogaster)
IP subcomplex [mitochondrial matrix] (Drosophila melanogaster)
NDUFS8:2x4Fe-4S [mitochondrial matrix] (Drosophila melanogaster)
NDUFS8 [mitochondrial matrix] (Drosophila melanogaster)
Intermediate 1 [mitochondrial inner membrane] (Drosophila melanogaster)
IP subcomplex [mitochondrial matrix] (Drosophila melanogaster)
NDUFS8:2x4Fe-4S [mitochondrial matrix] (Drosophila melanogaster)
NDUFS8 [mitochondrial matrix] (Drosophila melanogaster)
Intermediate 1 binds HP subcomplex to form Intermediate 2 (Drosophila melanogaster)
Intermediate 1 [mitochondrial inner membrane] (Drosophila melanogaster)
IP subcomplex [mitochondrial matrix] (Drosophila melanogaster)
NDUFS8:2x4Fe-4S [mitochondrial matrix] (Drosophila melanogaster)
NDUFS8 [mitochondrial matrix] (Drosophila melanogaster)
Intermediate 2 [mitochondrial inner membrane] (Drosophila melanogaster)
Intermediate 1 [mitochondrial inner membrane] (Drosophila melanogaster)
IP subcomplex [mitochondrial matrix] (Drosophila melanogaster)
NDUFS8:2x4Fe-4S [mitochondrial matrix] (Drosophila melanogaster)
NDUFS8 [mitochondrial matrix] (Drosophila melanogaster)
Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex (Drosophila melanogaster)
315kDa subcomplex [mitochondrial inner membrane] (Drosophila melanogaster)
Intermediate 2 [mitochondrial inner membrane] (Drosophila melanogaster)
Intermediate 1 [mitochondrial inner membrane] (Drosophila melanogaster)
IP subcomplex [mitochondrial matrix] (Drosophila melanogaster)
NDUFS8:2x4Fe-4S [mitochondrial matrix] (Drosophila melanogaster)
NDUFS8 [mitochondrial matrix] (Drosophila melanogaster)
Intermediate 2 [mitochondrial inner membrane] (Drosophila melanogaster)
Intermediate 1 [mitochondrial inner membrane] (Drosophila melanogaster)
IP subcomplex [mitochondrial matrix] (Drosophila melanogaster)
NDUFS8:2x4Fe-4S [mitochondrial matrix] (Drosophila melanogaster)
NDUFS8 [mitochondrial matrix] (Drosophila melanogaster)
ND4, ND5 bind the 550kDa complex to form the 815kDa complex (Drosophila melanogaster)
550kDa complex [mitochondrial inner membrane] (Drosophila melanogaster)
315kDa subcomplex [mitochondrial inner membrane] (Drosophila melanogaster)
Intermediate 2 [mitochondrial inner membrane] (Drosophila melanogaster)
Intermediate 1 [mitochondrial inner membrane] (Drosophila melanogaster)
IP subcomplex [mitochondrial matrix] (Drosophila melanogaster)
NDUFS8:2x4Fe-4S [mitochondrial matrix] (Drosophila melanogaster)
NDUFS8 [mitochondrial matrix] (Drosophila melanogaster)
815kDa complex [mitochondrial inner membrane] (Drosophila melanogaster)
550kDa complex [mitochondrial inner membrane] (Drosophila melanogaster)
315kDa subcomplex [mitochondrial inner membrane] (Drosophila melanogaster)
Intermediate 2 [mitochondrial inner membrane] (Drosophila melanogaster)
Intermediate 1 [mitochondrial inner membrane] (Drosophila melanogaster)
IP subcomplex [mitochondrial matrix] (Drosophila melanogaster)
NDUFS8:2x4Fe-4S [mitochondrial matrix] (Drosophila melanogaster)
NDUFS8 [mitochondrial matrix] (Drosophila melanogaster)
NDUF subunits bind to form the IP subcomplex (Drosophila melanogaster)
IP subcomplex [mitochondrial matrix] (Drosophila melanogaster)
NDUFS8:2x4Fe-4S [mitochondrial matrix] (Drosophila melanogaster)
NDUFS8 [mitochondrial matrix] (Drosophila melanogaster)
NDUFS8:2x4Fe-4S [mitochondrial matrix] (Drosophila melanogaster)
NDUFS8 [mitochondrial matrix] (Drosophila melanogaster)
NUBPL transfers 4Fe-4S to Complex I subunits (Drosophila melanogaster)
NDUF subunits [mitochondrial matrix] (Drosophila melanogaster)
NDUFS8 [mitochondrial matrix] (Drosophila melanogaster)
NDUF:4Fe-4S subunits [mitochondrial matrix] (Drosophila melanogaster)
NDUFS8:2x4Fe-4S [mitochondrial matrix] (Drosophila melanogaster)
NDUFS8 [mitochondrial matrix] (Drosophila melanogaster)
The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex (Drosophila melanogaster)
315kDa subcomplex [mitochondrial inner membrane] (Drosophila melanogaster)
Intermediate 2 [mitochondrial inner membrane] (Drosophila melanogaster)
Intermediate 1 [mitochondrial inner membrane] (Drosophila melanogaster)
IP subcomplex [mitochondrial matrix] (Drosophila melanogaster)
NDUFS8:2x4Fe-4S [mitochondrial matrix] (Drosophila melanogaster)
NDUFS8 [mitochondrial matrix] (Drosophila melanogaster)
550kDa complex [mitochondrial inner membrane] (Drosophila melanogaster)
315kDa subcomplex [mitochondrial inner membrane] (Drosophila melanogaster)
Intermediate 2 [mitochondrial inner membrane] (Drosophila melanogaster)
Intermediate 1 [mitochondrial inner membrane] (Drosophila melanogaster)
IP subcomplex [mitochondrial matrix] (Drosophila melanogaster)
NDUFS8:2x4Fe-4S [mitochondrial matrix] (Drosophila melanogaster)
NDUFS8 [mitochondrial matrix] (Drosophila melanogaster)
The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I (Drosophila melanogaster)
980kDa complex [mitochondrial inner membrane] (Drosophila melanogaster)
815kDa complex [mitochondrial inner membrane] (Drosophila melanogaster)
550kDa complex [mitochondrial inner membrane] (Drosophila melanogaster)
315kDa subcomplex [mitochondrial inner membrane] (Drosophila melanogaster)
Intermediate 2 [mitochondrial inner membrane] (Drosophila melanogaster)
Intermediate 1 [mitochondrial inner membrane] (Drosophila melanogaster)
IP subcomplex [mitochondrial matrix] (Drosophila melanogaster)
NDUFS8:2x4Fe-4S [mitochondrial matrix] (Drosophila melanogaster)
NDUFS8 [mitochondrial matrix] (Drosophila melanogaster)
Complex I [mitochondrial inner membrane] (Drosophila melanogaster)
815kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Drosophila melanogaster)
550kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Drosophila melanogaster)
315kDa subcomplex (-NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Drosophila melanogaster)
Intermediate 2 (-NDUFAF3,4,7,TIMMDC1) [mitochondrial inner membrane] (Drosophila melanogaster)
Intermediate 1 (-NDUFAF3,4,7, TIMMDC1) [mitochondrial inner membrane] (Drosophila melanogaster)
NDUFS8:2x4Fe-4S [mitochondrial matrix] (Drosophila melanogaster)
NDUFS8 [mitochondrial matrix] (Drosophila melanogaster)
Complex I oxidises NADH to NAD+, reduces CoQ to QH2 (Drosophila melanogaster)
Complex I [mitochondrial inner membrane] (Drosophila melanogaster)
815kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Drosophila melanogaster)
550kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Drosophila melanogaster)
315kDa subcomplex (-NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Drosophila melanogaster)
Intermediate 2 (-NDUFAF3,4,7,TIMMDC1) [mitochondrial inner membrane] (Drosophila melanogaster)
Intermediate 1 (-NDUFAF3,4,7, TIMMDC1) [mitochondrial inner membrane] (Drosophila melanogaster)
NDUFS8:2x4Fe-4S [mitochondrial matrix] (Drosophila melanogaster)
NDUFS8 [mitochondrial matrix] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9VF27
Reference Genes
BioGPS Gene:44207
ENSEMBL:FBgn0017567
Flybase:FBgn0017567
KEGG Gene (Drosophila melanogaster):Dmel_CG3944
Monarch:44207
NCBI Gene:44207
UCSC:Q9VF27
Reference Transcript
RefSeq:NM_079980.4
Other Identifiers
153134_at
1627220_at
44207
GO:0003824
GO:0003954
GO:0005215
GO:0005739
GO:0005747
GO:0006091
GO:0006120
GO:0007005
GO:0008137
GO:0009060
GO:0016020
GO:0016491
GO:0016651
GO:0032981
GO:0042775
GO:0043226
GO:0046872
GO:0051536
GO:0051539
GO:0065003
Participates
as a member of
NDUF subunits [mitochondrial matrix] (Drosophila melanogaster)
as a component of
NDUFS8:2x4Fe-4S [mitochondrial matrix] (Drosophila melanogaster)
Inferred From
NDUFS8 [mitochondrial matrix]
(Homo sapiens)
Cross References
RefSeq
NP_524719.1
Flybase
FBgn0017567
PDB
8ESZ
,
8BA0
,
8B9Z
,
8ESW
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