Reactome | NABP2 [nucleoplasm]

NABP2 [nucleoplasm]

Stable Identifier

R-DME-6814916

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

nucleoplasm

Synonyms

Q9VM17

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Drosophila melanogaster)

- RNA Polymerase II Transcription (Drosophila melanogaster)
  - RNA polymerase II transcribes snRNA genes (Drosophila melanogaster)
    - CBCAP complex binds 7-methylguanosine cap of snRNA (Drosophila melanogaster)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Drosophila melanogaster)
        
        Integrator [nucleoplasm] (Drosophila melanogaster)
        
        NABP1,2 [nucleoplasm] (Drosophila melanogaster)
        
        NABP2 [nucleoplasm] (Drosophila melanogaster)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Drosophila melanogaster)
        
        Integrator [nucleoplasm] (Drosophila melanogaster)
        
        NABP1,2 [nucleoplasm] (Drosophila melanogaster)
        
        NABP2 [nucleoplasm] (Drosophila melanogaster)
    - Integrator complex processes the 3' end of snRNA (Drosophila melanogaster)
      - Integrator [nucleoplasm] (Drosophila melanogaster)
        
        NABP1,2 [nucleoplasm] (Drosophila melanogaster)
        
        NABP2 [nucleoplasm] (Drosophila melanogaster)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Drosophila melanogaster)
        
        Integrator [nucleoplasm] (Drosophila melanogaster)
        
        NABP1,2 [nucleoplasm] (Drosophila melanogaster)
        
        NABP2 [nucleoplasm] (Drosophila melanogaster)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Drosophila melanogaster)
        
        Integrator [nucleoplasm] (Drosophila melanogaster)
        
        NABP1,2 [nucleoplasm] (Drosophila melanogaster)
        
        NABP2 [nucleoplasm] (Drosophila melanogaster)
    - Pre-snRNA is elongated and capped with 7-methylguanosine (Drosophila melanogaster)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Drosophila melanogaster)
        
        Integrator [nucleoplasm] (Drosophila melanogaster)
        
        NABP1,2 [nucleoplasm] (Drosophila melanogaster)
        
        NABP2 [nucleoplasm] (Drosophila melanogaster)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Drosophila melanogaster)
        
        Integrator [nucleoplasm] (Drosophila melanogaster)
        
        NABP1,2 [nucleoplasm] (Drosophila melanogaster)
        
        NABP2 [nucleoplasm] (Drosophila melanogaster)
    - Pre-snRNA transcript initiation, Integrator binding, LEC binding (Drosophila melanogaster)
      - Integrator [nucleoplasm] (Drosophila melanogaster)
        
        NABP1,2 [nucleoplasm] (Drosophila melanogaster)
        
        NABP2 [nucleoplasm] (Drosophila melanogaster)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Drosophila melanogaster)
        
        Integrator [nucleoplasm] (Drosophila melanogaster)
        
        NABP1,2 [nucleoplasm] (Drosophila melanogaster)
        
        NABP2 [nucleoplasm] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q9VM17

Reference Genes

BioGPS Gene:34018

ENSEMBL:FBgn0031909

FlyBase:FBgn0031909

KEGG:dme:Dmel_CG5181

Monarch:34018

NCBI Gene:34018

UCSC:Q9VM17

Reference Transcript

RefSeq:NM_135271.3

Other Identifiers

145954_at

1625658_at

34018

GO:0000724

GO:0003677

GO:0003697

GO:0005634

GO:0005737

GO:0006281

GO:0006310

GO:0010212

GO:0043226

GO:0070876

Participates

as a member of

NABP1,2 [nucleoplasm] (Drosophila melanogaster)

Other forms of this molecule

NABP1 [nucleoplasm]

Inferred From

NABP2 [nucleoplasm] (Homo sapiens)

Cross References

ENSEMBL

FBgn0031909, FBtr0079467, FBpp0079091

FlyBase

FBgn0031909

PRO

Q9VM17

Cite Us!