Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyze Data
Species Comparison
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site map
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyze Data
Species Comparison
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site map
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
phospho-p-T177-CDK6 [nucleoplasm]
Stable Identifier
R-DME-69628
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
nucleoplasm
Synonyms
Q7K306
Locations in the PathwayBrowser
Expand all
Cell Cycle (Drosophila melanogaster)
Cell Cycle, Mitotic (Drosophila melanogaster)
Mitotic G1 phase and G1/S transition (Drosophila melanogaster)
G1 Phase (Drosophila melanogaster)
Cyclin D associated events in G1 (Drosophila melanogaster)
CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6:CCND [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6 [nucleoplasm] (Drosophila melanogaster)
phospho-p-T177-CDK6 [nucleoplasm] (Drosophila melanogaster)
Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6:CCND [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6 [nucleoplasm] (Drosophila melanogaster)
phospho-p-T177-CDK6 [nucleoplasm] (Drosophila melanogaster)
Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6:CCND [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6 [nucleoplasm] (Drosophila melanogaster)
phospho-p-T177-CDK6 [nucleoplasm] (Drosophila melanogaster)
Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6:CCND [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6 [nucleoplasm] (Drosophila melanogaster)
phospho-p-T177-CDK6 [nucleoplasm] (Drosophila melanogaster)
RB1 binds and inhibits E2F1/2/3:DP1/2 complexes (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6:CCND [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6 [nucleoplasm] (Drosophila melanogaster)
phospho-p-T177-CDK6 [nucleoplasm] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q7K306
Reference Genes
BioGPS Gene:36854
ENSEMBL:FBgn0016131
Flybase:FBgn0016131
KEGG Gene (Drosophila melanogaster):Dmel_CG5072
Monarch:36854
NCBI Gene:36854
UCSC:Q7K306
Reference Transcript
RefSeq:NM_057848.3
RefSeq:NM_001299564.1
RefSeq:NM_166185.2
RefSeq:NM_166184.2
RefSeq:NM_001299565.1
Other Identifiers
154563_at
1639347_s_at
7227.FBpp0086249
AAF57980.1
AAF57981.1
AAM68505.1
AHN56289.1
AHN56290.1
AY060397
EntrezGene:36854
FBgn0016131
FBpp0086249
FBpp0086250
FBpp0086251
FBpp0309069
FBpp0311495
FBtr0087102
FBtr0087103
FBtr0087104
FBtr0340063
FBtr0345340
GO:0000082
GO:0000166
GO:0000278
GO:0000307
GO:0003674
GO:0004672
GO:0004674
GO:0004693
GO:0005524
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005737
GO:0006464
GO:0006468
GO:0007005
GO:0007049
GO:0007165
GO:0007350
GO:0007424
GO:0008150
GO:0008283
GO:0008284
GO:0009790
GO:0010033
GO:0010389
GO:0010468
GO:0010821
GO:0016301
GO:0016310
GO:0016740
GO:0030307
GO:0030332
GO:0032991
GO:0040007
GO:0043167
GO:0043226
GO:0046427
GO:0048856
GO:0051726
GO:1904263
IPR000719
IPR008271
IPR011009
IPR017441
NM_001299564.1
NM_001299565.1
NM_057848.3
NM_166184.2
NM_166185.2
NP_001286493.1
NP_001286494.1
NP_477196.1
NP_725594.1
NP_725595.1
NR_124576.1
PF00069
SM00220
UPI000007AE23
Participant Of
hasCandidate
p-T172-CDK4,p-T177-CDK6 [nucleoplasm]
Other forms of this molecule
CDK4 [cytosol]
CDK6 [cytosol]
CDK4 [nucleoplasm]
CDK6 [nucleoplasm]
phospho-p-T172-CDK4 [nucleoplasm]
Inferred From
p-T177-CDK6 [nucleoplasm] (Homo sapiens)
Modified Residues
Name
O-phospho-L-threonine at 177 (in Homo sapiens)
Coordinate
177
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Cross References
RefSeq
NP_725594.1
,
NP_725595.1
,
NP_477196.1
,
NP_001286493.1
,
NP_001286494.1
Flybase
FBgn0016131
© 2019
Reactome