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alpha-KGDHC [mitochondrial matrix]
Stable Identifier
R-DME-69993
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
mitochondrial matrix
Synonyms
Lipo-K110-DLST, Q9VGQ1
Locations in the PathwayBrowser
Expand all
Metabolism (Drosophila melanogaster)
Aerobic respiration and respiratory electron transport (Drosophila melanogaster)
Citric acid cycle (TCA cycle) (Drosophila melanogaster)
OGDH complex synthesizes succinyl-CoA from 2-OG (Drosophila melanogaster)
DLD dimer dehydrogenates dihydrolipoyl (Drosophila melanogaster)
OGDH complex [mitochondrial matrix] (Drosophila melanogaster)
lipo-DLST trimer [mitochondrial matrix] (Drosophila melanogaster)
alpha-KGDHC [mitochondrial matrix] (Drosophila melanogaster)
alpha-KGDHC [mitochondrial matrix] (Drosophila melanogaster)
DLST transfers succinyl to CoA (Drosophila melanogaster)
OGDH complex [mitochondrial matrix] (Drosophila melanogaster)
lipo-DLST trimer [mitochondrial matrix] (Drosophila melanogaster)
alpha-KGDHC [mitochondrial matrix] (Drosophila melanogaster)
lipo-DLST trimer [mitochondrial matrix] (Drosophila melanogaster)
alpha-KGDHC [mitochondrial matrix] (Drosophila melanogaster)
OGDH dimer decarboxylates 2-OG (Drosophila melanogaster)
OGDH complex [mitochondrial matrix] (Drosophila melanogaster)
lipo-DLST trimer [mitochondrial matrix] (Drosophila melanogaster)
alpha-KGDHC [mitochondrial matrix] (Drosophila melanogaster)
alpha-KGDHC [mitochondrial matrix] (Drosophila melanogaster)
Metabolism of amino acids and derivatives (Drosophila melanogaster)
Glyoxylate metabolism and glycine degradation (Drosophila melanogaster)
Glycine degradation (Drosophila melanogaster)
DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate (Drosophila melanogaster)
OGDH complex [mitochondrial matrix] (Drosophila melanogaster)
lipo-DLST trimer [mitochondrial matrix] (Drosophila melanogaster)
alpha-KGDHC [mitochondrial matrix] (Drosophila melanogaster)
Lysine catabolism (Drosophila melanogaster)
alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ (Drosophila melanogaster)
OADH complex [mitochondrial matrix] (Drosophila melanogaster)
lipo-DLST trimer [mitochondrial matrix] (Drosophila melanogaster)
alpha-KGDHC [mitochondrial matrix] (Drosophila melanogaster)
Metabolism of proteins (Drosophila melanogaster)
Post-translational protein modification (Drosophila melanogaster)
Protein lipoylation (Drosophila melanogaster)
LIPT1 transfers lipoyl group from lipoyl-GCSH to DBT/DLST (Drosophila melanogaster)
Lipoylated DBT/DLST [mitochondrial matrix] (Drosophila melanogaster)
alpha-KGDHC [mitochondrial matrix] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9VGQ1
Gene Names
alpha-KGDHC
Reference Genes
BioGPS Gene:41360 alpha-KGDHC
ENSEMBL:FBgn0037891
Flybase:FBgn0037891
KEGG Gene (Drosophila melanogaster):Dmel_CG5214 alpha-KGDHC
Monarch:41360 alpha-KGDHC
NCBI Gene:41360 alpha-KGDHC
UCSC:Q9VGQ1 alpha-KGDHC
Reference Transcript
RefSeq:NM_141807.2 alpha-KGDHC
Other Identifiers
153115_at
1639513_at
41360
GO:0003824
GO:0004149
GO:0005739
GO:0006091
GO:0006099
GO:0006520
GO:0006790
GO:0009353
GO:0016491
GO:0016740
GO:0016746
GO:0033512
GO:0034602
GO:0043226
GO:0045252
GO:0045333
GO:0055086
GO:0140096
GO:1901135
Participates
as a member of
Lipoylated DBT/DLST [mitochondrial matrix] (Drosophila melanogaster)
as an output of
DLD dimer dehydrogenates dihydrolipoyl (Drosophila melanogaster)
as an input of
OGDH dimer decarboxylates 2-OG (Drosophila melanogaster)
as a component of
lipo-DLST trimer [mitochondrial matrix] (Drosophila melanogaster)
Other forms of this molecule
alpha-KGDHC [mitochondrial matrix]
alpha-KGDHC [mitochondrial matrix]
alpha-KGDHC [mitochondrial matrix]
Inferred From
Lipo-K110-DLST [mitochondrial matrix]
(Homo sapiens)
Modified Residues
Name
N6-lipoyl-L-lysine at 110 (in Homo sapiens)
Coordinate
110
PsiMod Name
N6-lipoyl-L-lysine [MOD:00127]
PsiMod Definition
A protein modification that effectively converts an L-lysine residue to N6-lipoyl-L-lysine.
Cross References
RefSeq
NP_650064.1
Flybase
FBgn0037891
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9VMM7 Q9VMM7
0.462
2
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