Reactome | Tmf [cytosol]

Tmf [cytosol]

Stable Identifier

R-DME-8847539

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

cytosol

Synonyms

TMF1, Q9W3V2

Locations in the PathwayBrowser

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Vesicle-mediated transport (Drosophila melanogaster)

- Membrane Trafficking (Drosophila melanogaster)
  - Intra-Golgi and retrograde Golgi-to-ER traffic (Drosophila melanogaster)
    - Retrograde transport at the Trans-Golgi-Network (Drosophila melanogaster)
      - ARL1 recruits TGN Golgin homodimers (Drosophila melanogaster)
        
        AcG-ARFRP1:GTP:SYS1:MyrG-ARL1:GTP:TGN Golgin dimers [trans-Golgi network membrane] (Drosophila melanogaster)
        
        TGN Golgin dimers [cytosol] (Drosophila melanogaster)
        
        TMF1 dimer [cytosol] (Drosophila melanogaster)
        
        Tmf [cytosol] (Drosophila melanogaster)
        
        TGN Golgin dimers [cytosol] (Drosophila melanogaster)
        
        TMF1 dimer [cytosol] (Drosophila melanogaster)
        
        Tmf [cytosol] (Drosophila melanogaster)
      - Fusion of early-endosome derived vesicles at the TGN (Drosophila melanogaster)
        
        AcG-ARFRP1:GTP:SYS1:MyrG-ARL1:GTP:TGN Golgin dimers [trans-Golgi network membrane] (Drosophila melanogaster)
        
        TGN Golgin dimers [cytosol] (Drosophila melanogaster)
        
        TMF1 dimer [cytosol] (Drosophila melanogaster)
        
        Tmf [cytosol] (Drosophila melanogaster)
        
        RAB6:GTP:RIC1:RGP1:GARP complex:COG complex:AcM-ARFRP1:GTP:SYS1:MyrG-ARL1:GTP:Golgin dimers:STX6:STX16:VTI1A:VAMP4:early endosome-to-TGN cargo [trans-Golgi network membrane] (Drosophila melanogaster)
        
        AcG-ARFRP1:GTP:SYS1:MyrG-ARL1:GTP:TGN Golgin dimers [trans-Golgi network membrane] (Drosophila melanogaster)
        
        TGN Golgin dimers [cytosol] (Drosophila melanogaster)
        
        TMF1 dimer [cytosol] (Drosophila melanogaster)
        
        Tmf [cytosol] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q9W3V2

Gene Names

Tmf

Reference Genes

BioGPS Gene:31629 Tmf

ENSEMBL:FBgn0029912

Flybase:FBgn0029912

KEGG Gene (Drosophila melanogaster):Dmel_CG4557 Tmf

Monarch:31629 Tmf

NCBI Gene:31629 Tmf

UCSC:Q9W3V2 Tmf

Reference Transcript

RefSeq:NM_132132.3 Tmf

Other Identifiers

144623_at

1625546_at

31629

GO:0005783

GO:0005794

GO:0006891

GO:0006897

GO:0016192

GO:0031267

GO:0032588

GO:0038024

GO:0043226

GO:0099041

Participates

as a component of

TMF1 dimer [cytosol] (Drosophila melanogaster)

Inferred From

TMF1 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_572360.1

Flybase

FBgn0029912

PRO

Q9W3V2

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O18334 Rab6	17	RAB41 [Golgi membrane] (R-DME-8849603) RAB6A [endoplasmic reticulum membrane] (R-DME-8849253) RAB6B [endoplasmic reticulum membrane] (R-DME-8849252) RAB6A [trans-Golgi network membrane] (R-DME-6810981) RAB6B [trans-Golgi network membrane] (R-DME-6810985) RAB6B [Golgi membrane] (R-DME-8849249) GGC-RAB6A [trans-Golgi network membrane] (R-DME-8876079) GGC-RAB6B [trans-Golgi network membrane] (R-DME-8876081) GGC-RAB6A [cytosol] (R-DME-8874052) GGC-RAB6B [cytosol] (R-DME-8874055) GGC-RAB41 [cytosol] (R-DME-8874030) RAB41 [cytosol] (R-DME-8873689) RAB6A [cytosol] (R-DME-6810979) RAB6B [cytosol] (R-DME-6810983) RAB6A [plasma membrane] (R-DME-6804981) RAB6A [secretory granule membrane] (R-DME-6804970) Rab6 [Golgi membrane] (R-DME-2032727)	0.553	2