Reactome | Als2 [cytosol]

Als2 [cytosol]

Stable Identifier

R-DME-8875298

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

cytosol

Synonyms

ALS2, Q9VNZ8

Locations in the PathwayBrowser

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Signal Transduction (Drosophila melanogaster)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Drosophila melanogaster)
  - Signaling by Rho GTPases (Drosophila melanogaster)
    - RHO GTPase cycle (Drosophila melanogaster)
      - RAC1 GTPase cycle (Drosophila melanogaster)
        
        RAC1 GEFs activate RAC1 (Drosophila melanogaster)
        
        RAC1 GEFs [cytosol] (Drosophila melanogaster)
        
        Als2 [cytosol] (Drosophila melanogaster)

Vesicle-mediated transport (Drosophila melanogaster)

- Membrane Trafficking (Drosophila melanogaster)
  - Rab regulation of trafficking (Drosophila melanogaster)
    - RAB GEFs exchange GTP for GDP on RABs (Drosophila melanogaster)
      - RAB5 GEFs exchange GTP for GDP on RAB5 (Drosophila melanogaster)
        
        RAB5 GEFs [cytosol] (Drosophila melanogaster)
        
        ALS2 dimer [cytosol] (Drosophila melanogaster)
        
        Als2 [cytosol] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q9VNZ8

Gene Names

Als2

Reference Genes

BioGPS Gene:40410 Als2

ENSEMBL:FBgn0037116

Flybase:FBgn0037116

KEGG Gene (Drosophila melanogaster):Dmel_CG7158 Als2

Monarch:40410 Als2

NCBI Gene:40410 Als2

UCSC:Q9VNZ8 Als2

Reference Transcript

RefSeq:NM_141090.3 Als2

Other Identifiers

154640_at

1634116_at

40410

GO:0002376

GO:0005085

GO:0005096

GO:0005737

GO:0005768

GO:0005769

GO:0005829

GO:0007032

GO:0016192

GO:0016197

GO:0023052

GO:0031267

GO:0031410

GO:0031982

GO:0032483

GO:0035011

GO:0043087

GO:0043226

GO:0043231

GO:0043547

GO:0045022

GO:0098542

GO:0098772

Participates

as a component of

ALS2 dimer [cytosol] (Drosophila melanogaster)

as a candidate of

RAC1 GEFs [cytosol] (Drosophila melanogaster)

Other forms of this molecule

Als2 [cytosol]

Inferred From

ALS2 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_649347.1

Flybase

FBgn0037116

PRO

Q9VNZ8

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