Reactome | Ghost homologue of p-8Y-EPOR [plasma membrane]

Ghost homologue of p-8Y-EPOR [plasma membrane]

Stable Identifier

R-DME-9006274

Type

Genes and Transcripts [GenomeEncodedEntity]

Species

Drosophila melanogaster

Compartment

plasma membrane

Locations in the PathwayBrowser

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Signal Transduction (Drosophila melanogaster)

- Signaling by Erythropoietin (Drosophila melanogaster)
  - Erythropoietin activates Phosphoinositide-3-kinase (PI3K) (Drosophila melanogaster)
    - EPOR-associated PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
      - EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-Y-GAB1:PI3K [plasma membrane] (Drosophila melanogaster)
        
        EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-Y-GAB1 [plasma membrane] (Drosophila melanogaster)
        
        EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2 [plasma membrane] (Drosophila melanogaster)
        
        p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2 [plasma membrane] (Drosophila melanogaster)
        
        Ghost homologue of p-8Y-EPOR [plasma membrane] (Drosophila melanogaster)
  - Erythropoietin activates RAS (Drosophila melanogaster)
    - EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:phospho-CRKL:RAPGEF1:phospho-SHC1 binds GRB2:VAV1 (Drosophila melanogaster)
      - EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-CRKL:RAPGEF1:p-Y-SHC1 [plasma membrane] (Drosophila melanogaster)
        
        EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-CRKL:RAPGEF1 [plasma membrane] (Drosophila melanogaster)
        
        EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2 [plasma membrane] (Drosophila melanogaster)
        
        p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2 [plasma membrane] (Drosophila melanogaster)
        
        Ghost homologue of p-8Y-EPOR [plasma membrane] (Drosophila melanogaster)
      - EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-CRKL:RAPGEF1:p-Y-SHC1:GRB2:VAV1 [plasma membrane] (Drosophila melanogaster)
        
        EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-CRKL:RAPGEF1:p-Y-SHC1 [plasma membrane] (Drosophila melanogaster)
        
        EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-CRKL:RAPGEF1 [plasma membrane] (Drosophila melanogaster)
        
        EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2 [plasma membrane] (Drosophila melanogaster)
        
        p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2 [plasma membrane] (Drosophila melanogaster)
        
        Ghost homologue of p-8Y-EPOR [plasma membrane] (Drosophila melanogaster)

Participates

as a component of

p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2 [plasma membrane] (Drosophila melanogaster)

Inferred From

p-8Y-EPOR [plasma membrane] (Homo sapiens)

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