Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
phospho-Cbl [cytosol]
Stable Identifier
R-DME-912656
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
p-Y700,Y731,Y774-CBL, Q9VSK2
Locations in the PathwayBrowser
Expand all
Immune System (Drosophila melanogaster)
Cytokine Signaling in Immune system (Drosophila melanogaster)
Signaling by Interleukins (Drosophila melanogaster)
Interleukin-3, Interleukin-5 and GM-CSF signaling (Drosophila melanogaster)
Regulation of signaling by CBL (Drosophila melanogaster)
CBL binds CRK (Drosophila melanogaster)
p(Y700,731,774)-CBL:CRK [cytosol] (Drosophila melanogaster)
phospho-Cbl [cytosol] (Drosophila melanogaster)
phospho-Cbl [cytosol] (Drosophila melanogaster)
CBL binds VAV (Drosophila melanogaster)
p(Y700,731,774)-CBL:VAV1 [cytosol] (Drosophila melanogaster)
phospho-Cbl [cytosol] (Drosophila melanogaster)
phospho-Cbl [cytosol] (Drosophila melanogaster)
CBL ubiquitinates PI3K (Drosophila melanogaster)
FYN-like kinases:p(Y731)-CBL:GRB2:Ubiquitinated p85-containing Class 1A PI3Ks [cytosol] (Drosophila melanogaster)
phospho-Cbl [cytosol] (Drosophila melanogaster)
FYN-like kinases:p(Y731)-CBL:GRB2:p85-containing Class 1A PI3Ks [cytosol] (Drosophila melanogaster)
phospho-Cbl [cytosol] (Drosophila melanogaster)
CBL:CRKL binds RAPGEF1 (Drosophila melanogaster)
p(Y700,731,774)-CBL:CRK [cytosol] (Drosophila melanogaster)
phospho-Cbl [cytosol] (Drosophila melanogaster)
p(Y700,731,774)-CBL:CRK:RAPGEF1 [cytosol] (Drosophila melanogaster)
p(Y700,731,774)-CBL:CRK [cytosol] (Drosophila melanogaster)
phospho-Cbl [cytosol] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Signaling by Non-Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by PTK6 (Drosophila melanogaster)
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 (Drosophila melanogaster)
CBL autoubiquitinates (Drosophila melanogaster)
phospho-Cbl [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9VSK2
Gene Names
Cbl
Reference Genes
BioGPS Gene:38961 Cbl
ENSEMBL:FBgn0020224
Flybase:FBgn0020224
KEGG Gene (Drosophila melanogaster):Dmel_CG7037 Cbl
Monarch:38961 Cbl
NCBI Gene:38961 Cbl
UCSC:Q9VSK2 Cbl
Reference Transcript
RefSeq:NM_139967.2 Cbl
Other Identifiers
148403_at
1635580_at
38961
GO:0001754
GO:0001784
GO:0003824
GO:0004842
GO:0005509
GO:0005515
GO:0005737
GO:0005886
GO:0005938
GO:0006508
GO:0006511
GO:0006513
GO:0007163
GO:0007165
GO:0007166
GO:0007175
GO:0007465
GO:0007476
GO:0008069
GO:0008270
GO:0009950
GO:0009953
GO:0012501
GO:0016192
GO:0016567
GO:0016740
GO:0017124
GO:0022414
GO:0023051
GO:0023052
GO:0030154
GO:0030163
GO:0030971
GO:0032353
GO:0036211
GO:0042059
GO:0042127
GO:0043065
GO:0045121
GO:0045746
GO:0046872
GO:0047690
GO:0048134
GO:0048260
GO:0048856
GO:0048870
GO:0060255
GO:0061630
GO:0070373
GO:0140096
GO:1903688
Participates
as an input of
CBL binds VAV (Drosophila melanogaster)
CBL binds CRK (Drosophila melanogaster)
CBL autoubiquitinates (Drosophila melanogaster)
as a component of
p(Y700,731,774)-CBL:VAV1 [cytosol] (Drosophila melanogaster)
FYN-like kinases:p(Y731)-CBL:GRB2:Ubiquitinated p85-containing Class 1A PI3Ks [cytosol] (Drosophila melanogaster)
FYN-like kinases:p(Y731)-CBL:GRB2:p85-containing Class 1A PI3Ks [cytosol] (Drosophila melanogaster)
p(Y700,731,774)-CBL:CRK [cytosol] (Drosophila melanogaster)
Other forms of this molecule
phospho-Cbl [cytosol]
phospho-Cbl [plasma membrane]
phospho-Cbl [cytosol]
Cbl [cytosol]
Cbl [cytosol]
Inferred From
p-Y700,Y731,Y774-CBL [cytosol]
(Homo sapiens)
Modified Residues
Name
O4'-phospho-L-tyrosine at 731 (in Homo sapiens)
Coordinate
731
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 700 (in Homo sapiens)
Coordinate
700
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 774 (in Homo sapiens)
Coordinate
774
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
RefSeq
NP_648224.1
Flybase
FBgn0020224
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text