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phospho-p-2S,S376,T,T209,T387-IRAK1 [plasma membrane]
Stable Identifier
R-DME-937011
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
plasma membrane
Synonyms
Q05652
Locations in the PathwayBrowser
Expand all
Immune System (Drosophila melanogaster)
Innate Immune System (Drosophila melanogaster)
Toll-like Receptor Cascades (Drosophila melanogaster)
Toll Like Receptor 10 (TLR10) Cascade (Drosophila melanogaster)
MyD88 cascade initiated on plasma membrane (Drosophila melanogaster)
IRAK1 recruits IKK complex (Drosophila melanogaster)
IRAK1 phosphorylates Pellino (Drosophila melanogaster)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Drosophila melanogaster)
TRAF6:hp-IRAK1 [plasma membrane] (Drosophila melanogaster)
phospho-p-2S,S376,T,T209,T387-IRAK1 [plasma membrane] (Drosophila melanogaster)
phospho-p-2S,S376,T,T209,T387-IRAK1 [plasma membrane] (Drosophila melanogaster)
Pellino binds hp-IRAK1:TRAF6 (Drosophila melanogaster)
TRAF6:hp-IRAK1 [plasma membrane] (Drosophila melanogaster)
phospho-p-2S,S376,T,T209,T387-IRAK1 [plasma membrane] (Drosophila melanogaster)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Drosophila melanogaster)
TRAF6:hp-IRAK1 [plasma membrane] (Drosophila melanogaster)
phospho-p-2S,S376,T,T209,T387-IRAK1 [plasma membrane] (Drosophila melanogaster)
Pellino ubiquitinates hp-IRAK1 (Drosophila melanogaster)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Drosophila melanogaster)
TRAF6:hp-IRAK1 [plasma membrane] (Drosophila melanogaster)
phospho-p-2S,S376,T,T209,T387-IRAK1 [plasma membrane] (Drosophila melanogaster)
Toll Like Receptor 2 (TLR2) Cascade (Drosophila melanogaster)
Toll Like Receptor TLR1:TLR2 Cascade (Drosophila melanogaster)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Drosophila melanogaster)
IRAK1 recruits IKK complex (Drosophila melanogaster)
IRAK1 phosphorylates Pellino (Drosophila melanogaster)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Drosophila melanogaster)
TRAF6:hp-IRAK1 [plasma membrane] (Drosophila melanogaster)
phospho-p-2S,S376,T,T209,T387-IRAK1 [plasma membrane] (Drosophila melanogaster)
phospho-p-2S,S376,T,T209,T387-IRAK1 [plasma membrane] (Drosophila melanogaster)
Pellino binds hp-IRAK1:TRAF6 (Drosophila melanogaster)
TRAF6:hp-IRAK1 [plasma membrane] (Drosophila melanogaster)
phospho-p-2S,S376,T,T209,T387-IRAK1 [plasma membrane] (Drosophila melanogaster)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Drosophila melanogaster)
TRAF6:hp-IRAK1 [plasma membrane] (Drosophila melanogaster)
phospho-p-2S,S376,T,T209,T387-IRAK1 [plasma membrane] (Drosophila melanogaster)
Pellino ubiquitinates hp-IRAK1 (Drosophila melanogaster)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Drosophila melanogaster)
TRAF6:hp-IRAK1 [plasma membrane] (Drosophila melanogaster)
phospho-p-2S,S376,T,T209,T387-IRAK1 [plasma membrane] (Drosophila melanogaster)
Toll Like Receptor TLR6:TLR2 Cascade (Drosophila melanogaster)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Drosophila melanogaster)
IRAK1 recruits IKK complex (Drosophila melanogaster)
IRAK1 phosphorylates Pellino (Drosophila melanogaster)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Drosophila melanogaster)
TRAF6:hp-IRAK1 [plasma membrane] (Drosophila melanogaster)
phospho-p-2S,S376,T,T209,T387-IRAK1 [plasma membrane] (Drosophila melanogaster)
phospho-p-2S,S376,T,T209,T387-IRAK1 [plasma membrane] (Drosophila melanogaster)
Pellino binds hp-IRAK1:TRAF6 (Drosophila melanogaster)
TRAF6:hp-IRAK1 [plasma membrane] (Drosophila melanogaster)
phospho-p-2S,S376,T,T209,T387-IRAK1 [plasma membrane] (Drosophila melanogaster)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Drosophila melanogaster)
TRAF6:hp-IRAK1 [plasma membrane] (Drosophila melanogaster)
phospho-p-2S,S376,T,T209,T387-IRAK1 [plasma membrane] (Drosophila melanogaster)
Pellino ubiquitinates hp-IRAK1 (Drosophila melanogaster)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Drosophila melanogaster)
TRAF6:hp-IRAK1 [plasma membrane] (Drosophila melanogaster)
phospho-p-2S,S376,T,T209,T387-IRAK1 [plasma membrane] (Drosophila melanogaster)
Toll Like Receptor 4 (TLR4) Cascade (Drosophila melanogaster)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Drosophila melanogaster)
IRAK1 recruits IKK complex (Drosophila melanogaster)
IRAK1 phosphorylates Pellino (Drosophila melanogaster)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Drosophila melanogaster)
TRAF6:hp-IRAK1 [plasma membrane] (Drosophila melanogaster)
phospho-p-2S,S376,T,T209,T387-IRAK1 [plasma membrane] (Drosophila melanogaster)
phospho-p-2S,S376,T,T209,T387-IRAK1 [plasma membrane] (Drosophila melanogaster)
Pellino binds hp-IRAK1:TRAF6 (Drosophila melanogaster)
TRAF6:hp-IRAK1 [plasma membrane] (Drosophila melanogaster)
phospho-p-2S,S376,T,T209,T387-IRAK1 [plasma membrane] (Drosophila melanogaster)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Drosophila melanogaster)
TRAF6:hp-IRAK1 [plasma membrane] (Drosophila melanogaster)
phospho-p-2S,S376,T,T209,T387-IRAK1 [plasma membrane] (Drosophila melanogaster)
Pellino ubiquitinates hp-IRAK1 (Drosophila melanogaster)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Drosophila melanogaster)
TRAF6:hp-IRAK1 [plasma membrane] (Drosophila melanogaster)
phospho-p-2S,S376,T,T209,T387-IRAK1 [plasma membrane] (Drosophila melanogaster)
Toll Like Receptor 5 (TLR5) Cascade (Drosophila melanogaster)
MyD88 cascade initiated on plasma membrane (Drosophila melanogaster)
IRAK1 recruits IKK complex (Drosophila melanogaster)
IRAK1 phosphorylates Pellino (Drosophila melanogaster)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Drosophila melanogaster)
TRAF6:hp-IRAK1 [plasma membrane] (Drosophila melanogaster)
phospho-p-2S,S376,T,T209,T387-IRAK1 [plasma membrane] (Drosophila melanogaster)
phospho-p-2S,S376,T,T209,T387-IRAK1 [plasma membrane] (Drosophila melanogaster)
Pellino binds hp-IRAK1:TRAF6 (Drosophila melanogaster)
TRAF6:hp-IRAK1 [plasma membrane] (Drosophila melanogaster)
phospho-p-2S,S376,T,T209,T387-IRAK1 [plasma membrane] (Drosophila melanogaster)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Drosophila melanogaster)
TRAF6:hp-IRAK1 [plasma membrane] (Drosophila melanogaster)
phospho-p-2S,S376,T,T209,T387-IRAK1 [plasma membrane] (Drosophila melanogaster)
Pellino ubiquitinates hp-IRAK1 (Drosophila melanogaster)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Drosophila melanogaster)
TRAF6:hp-IRAK1 [plasma membrane] (Drosophila melanogaster)
phospho-p-2S,S376,T,T209,T387-IRAK1 [plasma membrane] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q05652 pll
Gene Names
pll, CG5974
Chain
chain:1-501
Reference Genes
BioGPS Gene:43283 pll
KEGG Gene (Drosophila melanogaster):Dmel_CG5974 pll
Monarch:43283 pll
NCBI Gene:43283 pll
UCSC:Q05652 pll
Reference Transcript
RefSeq:NM_001276079.1 pll
RefSeq:NM_057623.4 pll
Other Identifiers
142881_at
1638252_at
43283
GO:0000166
GO:0002376
GO:0002804
GO:0003824
GO:0004672
GO:0004674
GO:0005515
GO:0005524
GO:0005634
GO:0005737
GO:0005829
GO:0005886
GO:0006468
GO:0006915
GO:0007165
GO:0007352
GO:0007526
GO:0008063
GO:0009953
GO:0012501
GO:0016020
GO:0016301
GO:0016310
GO:0016740
GO:0019221
GO:0019904
GO:0023052
GO:0030163
GO:0035172
GO:0035332
GO:0035556
GO:0036211
GO:0043226
GO:0045087
GO:0045732
GO:0046777
GO:0048262
GO:0048583
GO:0048856
GO:0061760
GO:0098542
GO:0106310
GO:0140096
GO:2000060
Participates
as a component of
TRAF6:hp-IRAK1 [plasma membrane] (Drosophila melanogaster)
Other forms of this molecule
Phospho PLL [cytosol]
PLL [cytosol]
phospho-K63polyUb-hp-IRAK1 [endosome membrane]
phospho-K63polyUb-hp-IRAK1 [cytosol]
phospho-p-IRAK2 [endosome membrane]
phospho-p-2S,S376,T,T209,T387-IRAK1 [endosome membrane]
phospho-p-IRAK2 [plasma membrane]
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol]
phospho-p-IRAK2 [cytosol]
IRAK4 [cytosol]
Inferred From
p-2S,S376,T,T209,T387-IRAK1 [plasma membrane]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-threonine at 387 (in Homo sapiens)
Coordinate
387
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-serine at 376 (in Homo sapiens)
Coordinate
376
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-threonine at 209 (in Homo sapiens)
Coordinate
209
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-serine at unknown position
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at unknown position
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-threonine at unknown position
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Cross References
RefSeq
NP_001263008.1
,
NP_476971.1
Flybase
FBgn0010441
PRO
Q05652
PDB
1YGO
,
1IK7
,
1D2Z
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P22812 tub
1
TUB [cytosol]
(R-DME-206155)
0.927
12
UniProt:O77237
6
Pli [cytosol]
(R-DME-450695)
Pli [cytosol]
(R-DME-450694)
Pli [cytosol]
(R-DME-450696)
phospho-Pli [cytosol]
(R-DME-450825)
phospho-Pli [cytosol]
(R-DME-450815)
phospho-Pli [cytosol]
(R-DME-450806)
0.59
3
UniProt:P15330 dl
13
dl [nucleoplasm]
(R-DME-177676)
dl [cytosol]
(R-DME-168172)
dl [cytosol]
(R-DME-5607652)
dl [cytosol]
(R-DME-1168579)
dl [nucleoplasm]
(R-DME-1168585)
phospho-dl [nucleoplasm]
(R-DME-5624468)
dl [nucleoplasm]
(R-DME-5607656)
phospho-dl [nucleoplasm]
(R-DME-5660642)
dl [nucleoplasm]
(R-DME-4755466)
dl [nucleoplasm]
(R-DME-8865233)
Phospho DL [nucleoplasm]
(R-DME-214731)
Phospho DL [cytosol]
(R-DME-214732)
DL [cytosol]
(R-DME-206011)
0.502
3
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