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About
What is Reactome ?
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Ub-139-UBC(77-152) [cytosol]
Stable Identifier
R-DME-939254
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
Q9W418
Locations in the PathwayBrowser
Expand all
Immune System (Drosophila melanogaster)
Cytokine Signaling in Immune system (Drosophila melanogaster)
Signaling by Interleukins (Drosophila melanogaster)
Interleukin-1 family signaling (Drosophila melanogaster)
Interleukin-1 signaling (Drosophila melanogaster)
Pellino ubiquitinates IRAK1 (Drosophila melanogaster)
hp-IRAK1: p-Pellino-1,2,(3):UBE2N:UBE2V1:K63polyUb [cytosol] (Drosophila melanogaster)
UBE2N:UBE2V1:K63polyUb [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
TRAF6 is K63 poly-ubiquitinated (Drosophila melanogaster)
hp-IRAK1:3xTRAF6:3xUBE2N:UBE2V1:K63polyUb [cytosol] (Drosophila melanogaster)
UBE2N:UBE2V1:K63polyUb [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
hp-IRAK1:3xTRAF6 binds UBE2N:UBE2V1:K63-polyUb (Drosophila melanogaster)
UBE2N:UBE2V1:K63polyUb [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
hp-IRAK1:3xTRAF6:3xUBE2N:UBE2V1:K63polyUb [cytosol] (Drosophila melanogaster)
UBE2N:UBE2V1:K63polyUb [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
hp-IRAK1:p-Pellino, IRAK4:p-Pellino bind UBE2N:UBE2V1 (Drosophila melanogaster)
IRAK1:Pellino:E2 complexes [cytosol] (Drosophila melanogaster)
IRAK4: p-Pellino-1,2,3:UBE2N:UBE2V1:K63polyUb [cytosol] (Drosophila melanogaster)
UBE2N:UBE2V1:K63polyUb [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
hp-IRAK1: p-Pellino-1,2,(3):UBE2N:UBE2V1:K63polyUb [cytosol] (Drosophila melanogaster)
UBE2N:UBE2V1:K63polyUb [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
UBE2N:UBE2V1:K63polyUb [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
Interleukin-17 signaling (Drosophila melanogaster)
MAP kinase activation (Drosophila melanogaster)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Drosophila melanogaster)
Activated TAK1 phosphorylates MKK4/MKK7 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
activated TAK1 mediates p38 MAPK activation (Drosophila melanogaster)
activated human TAK1 phosphorylates MKK3/MKK6 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
Innate Immune System (Drosophila melanogaster)
Toll-like Receptor Cascades (Drosophila melanogaster)
Toll Like Receptor 10 (TLR10) Cascade (Drosophila melanogaster)
MyD88 cascade initiated on plasma membrane (Drosophila melanogaster)
IRAK1 recruits IKK complex (Drosophila melanogaster)
Pellino ubiquitinates hp-IRAK1 (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
IRAK2 mediated activation of TAK1 complex (Drosophila melanogaster)
Activated TRAF6 synthesizes unanchored polyubiquitin chains (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
MAP kinase activation (Drosophila melanogaster)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Drosophila melanogaster)
Activated TAK1 phosphorylates MKK4/MKK7 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
activated TAK1 mediates p38 MAPK activation (Drosophila melanogaster)
activated human TAK1 phosphorylates MKK3/MKK6 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
Toll Like Receptor 2 (TLR2) Cascade (Drosophila melanogaster)
Toll Like Receptor TLR1:TLR2 Cascade (Drosophila melanogaster)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Drosophila melanogaster)
IRAK1 recruits IKK complex (Drosophila melanogaster)
Pellino ubiquitinates hp-IRAK1 (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
IRAK2 mediated activation of TAK1 complex (Drosophila melanogaster)
Activated TRAF6 synthesizes unanchored polyubiquitin chains (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
MAP kinase activation (Drosophila melanogaster)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Drosophila melanogaster)
Activated TAK1 phosphorylates MKK4/MKK7 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
activated TAK1 mediates p38 MAPK activation (Drosophila melanogaster)
activated human TAK1 phosphorylates MKK3/MKK6 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
Toll Like Receptor TLR6:TLR2 Cascade (Drosophila melanogaster)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Drosophila melanogaster)
IRAK1 recruits IKK complex (Drosophila melanogaster)
Pellino ubiquitinates hp-IRAK1 (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
IRAK2 mediated activation of TAK1 complex (Drosophila melanogaster)
Activated TRAF6 synthesizes unanchored polyubiquitin chains (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
MAP kinase activation (Drosophila melanogaster)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Drosophila melanogaster)
Activated TAK1 phosphorylates MKK4/MKK7 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
activated TAK1 mediates p38 MAPK activation (Drosophila melanogaster)
activated human TAK1 phosphorylates MKK3/MKK6 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
Toll Like Receptor 3 (TLR3) Cascade (Drosophila melanogaster)
MAP kinase activation (Drosophila melanogaster)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Drosophila melanogaster)
Activated TAK1 phosphorylates MKK4/MKK7 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
activated TAK1 mediates p38 MAPK activation (Drosophila melanogaster)
activated human TAK1 phosphorylates MKK3/MKK6 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
Toll Like Receptor 4 (TLR4) Cascade (Drosophila melanogaster)
MyD88-independent TLR4 cascade (Drosophila melanogaster)
TRIF(TICAM1)-mediated TLR4 signaling (Drosophila melanogaster)
MAP kinase activation (Drosophila melanogaster)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Drosophila melanogaster)
Activated TAK1 phosphorylates MKK4/MKK7 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
activated TAK1 mediates p38 MAPK activation (Drosophila melanogaster)
activated human TAK1 phosphorylates MKK3/MKK6 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
TRAF6-mediated induction of TAK1 complex within TLR4 complex (Drosophila melanogaster)
Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Drosophila melanogaster)
IRAK1 recruits IKK complex (Drosophila melanogaster)
Pellino ubiquitinates hp-IRAK1 (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
IRAK2 mediated activation of TAK1 complex (Drosophila melanogaster)
Activated TRAF6 synthesizes unanchored polyubiquitin chains (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
MAP kinase activation (Drosophila melanogaster)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Drosophila melanogaster)
Activated TAK1 phosphorylates MKK4/MKK7 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
activated TAK1 mediates p38 MAPK activation (Drosophila melanogaster)
activated human TAK1 phosphorylates MKK3/MKK6 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
Toll Like Receptor 5 (TLR5) Cascade (Drosophila melanogaster)
MyD88 cascade initiated on plasma membrane (Drosophila melanogaster)
IRAK1 recruits IKK complex (Drosophila melanogaster)
Pellino ubiquitinates hp-IRAK1 (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
IRAK2 mediated activation of TAK1 complex (Drosophila melanogaster)
Activated TRAF6 synthesizes unanchored polyubiquitin chains (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
MAP kinase activation (Drosophila melanogaster)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Drosophila melanogaster)
Activated TAK1 phosphorylates MKK4/MKK7 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
activated TAK1 mediates p38 MAPK activation (Drosophila melanogaster)
activated human TAK1 phosphorylates MKK3/MKK6 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Drosophila melanogaster)
MyD88 dependent cascade initiated on endosome (Drosophila melanogaster)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Drosophila melanogaster)
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation (Drosophila melanogaster)
Pellino ubiquitinates hp-IRAK1 upon TLR7/8 or 9 activation
(Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Drosophila melanogaster)
Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
MAP kinase activation (Drosophila melanogaster)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Drosophila melanogaster)
Activated TAK1 phosphorylates MKK4/MKK7 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
activated TAK1 mediates p38 MAPK activation (Drosophila melanogaster)
activated human TAK1 phosphorylates MKK3/MKK6 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
Toll Like Receptor 9 (TLR9) Cascade (Drosophila melanogaster)
MyD88 dependent cascade initiated on endosome (Drosophila melanogaster)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Drosophila melanogaster)
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation (Drosophila melanogaster)
Pellino ubiquitinates hp-IRAK1 upon TLR7/8 or 9 activation
(Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Drosophila melanogaster)
Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
MAP kinase activation (Drosophila melanogaster)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Drosophila melanogaster)
Activated TAK1 phosphorylates MKK4/MKK7 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
activated TAK1 mediates p38 MAPK activation (Drosophila melanogaster)
activated human TAK1 phosphorylates MKK3/MKK6 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
Metabolism of proteins (Drosophila melanogaster)
Post-translational protein modification (Drosophila melanogaster)
Deubiquitination (Drosophila melanogaster)
Josephin domain DUBs (Drosophila melanogaster)
ATXN3 family cleave Ub chains (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
PARK2 autoubiquitinates (Drosophila melanogaster)
PolyUb [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
Metalloprotease DUBs (Drosophila melanogaster)
PSMD14 cleaves K63-linked ubiquitin (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
STAMBPL1 is a deubiquitinase (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
Ovarian tumor domain proteases (Drosophila melanogaster)
TNFAIP3 (A20) deubiquitinates K63polyUb-RIPK1 (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
Ub-specific processing proteases (Drosophila melanogaster)
CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
USP11 deubiquitinates NFKBIA (Drosophila melanogaster)
PolyUb [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
USP13 deubiquitinates BECN1,USP10 (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 (Drosophila melanogaster)
PolyUb [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
USP20, USP33 deubiquitinate ADRB2 (Drosophila melanogaster)
PolyUb [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
USP21 deubiquitinates RIPK1,DDX58 (Drosophila melanogaster)
PolyUb [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
USP33 deubiquitinates CCP110,ARRB (Drosophila melanogaster)
PolyUb [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
USP4 deubiquitinate TRAF2,TRAF6 (Drosophila melanogaster)
PolyUb [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
USP5 cleaves polyubiquitin (Drosophila melanogaster)
USP5:PolyUb [cytosol] (Drosophila melanogaster)
PolyUb [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
K63-Ub [cytosol] (Drosophila melanogaster)
Ub-139-UBC(77-152) [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9W418
Reference Genes
BioGPS Gene:326237
ENSEMBL:FBgn0086558
Flybase:FBgn0086558
KEGG Gene (Drosophila melanogaster):Dmel_CG32744
Monarch:326237
NCBI Gene:326237
UCSC:Q9W418
Reference Transcript
RefSeq:NM_167065.3
RefSeq:NM_001298008.1
Other Identifiers
144587_f_at
1623505_s_at
1630005_at
7227.FBpp0070894
AAF46142.3
AHN59408.1
BT044587
EntrezGene:326237
FBgn0086558
FBpp0070894
FBpp0311816
FBtr0070933
FBtr0345892
GO:0003674
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005694
GO:0005704
GO:0005737
GO:0006464
GO:0006511
GO:0008150
GO:0009056
GO:0016567
GO:0019899
GO:0019941
GO:0031386
GO:0031625
GO:0043226
IPR000626
IPR019954
IPR019956
IPR029071
NM_001298008.1
NM_167065.3
NP_001284937.1
NP_727078.1
PF00240
PR00348
SM00213
UPI000007FAA1
Participant Of
hasMember
K63-Ub [cytosol]
Other forms of this molecule
Ub-566-UBC(533-608) [mitochondrial outer membrane]
Ub-338-UBC(305-380) [mitochondrial outer membrane]
Ub-186-UBC(153-228) [mitochondrial outer membrane]
Ub-262-UBC(229-304) [mitochondrial outer membrane]
Ub-414-UBC(381-456) [mitochondrial outer membrane]
Ub-110-UBC(77-152) [mitochondrial outer membrane]
Ub-642-UBC(609-684) [mitochondrial outer membrane]
Ub-33-UBC(1-76) [mitochondrial outer membrane]
Ub-488-UBC(457-532) [mitochondrial outer membrane]
Ub-291-UBC(229-304) [mitochondrial outer membrane]
Ub-595-UBC(533-608) [mitochondrial outer membrane]
Ub-443-UBC(381-456) [mitochondrial outer membrane]
Ub-139-UBC(77-152) [mitochondrial outer membrane]
Ub-63-UBC(1-76) [mitochondrial outer membrane]
Ub-671-UBC(609-684) [mitochondrial outer membrane]
Ub-519-UBC(457-532) [mitochondrial outer membrane]
Ub-367-UBC(305-380) [mitochondrial outer membrane]
Ub-215-UBC(153-228) [mitochondrial outer membrane]
Ub-386-UBC(381-456) [mitochondrial outer membrane]
Ub-6-UBC(1-76) [mitochondrial outer membrane]
Ub-310-UBC(305-380) [mitochondrial outer membrane]
Ub-234-UBC(229-304) [mitochondrial outer membrane]
Ub-614-UBC(609-684) [mitochondrial outer membrane]
Ub-462-UBC(457-532) [mitochondrial outer membrane]
Ub-538-UBC(533-608) [mitochondrial outer membrane]
Ub-158-UBC(153-228) [mitochondrial outer membrane]
Ub-82-UBC(77-152) [mitochondrial outer membrane]
Ub-315-UBC(305-380) [mitochondrial outer membrane]
Ub-163-UBC(153-228) [mitochondrial outer membrane]
Ub-543-UBC(533-608) [mitochondrial outer membrane]
Ub-239-UBC(229-304) [mitochondrial outer membrane]
Ub-619-UBC(609-684) [mitochondrial outer membrane]
Ub-467-UBC(457-532) [mitochondrial outer membrane]
Ub-11-UBC(1-76) [mitochondrial outer membrane]
Ub-391-UBC(381-456) [mitochondrial outer membrane]
Ub-87-UBC(77-152) [mitochondrial outer membrane]
Ub-656-UBC(609-684) [mitochondrial outer membrane]
Ub-124-UBC(77-152) [mitochondrial outer membrane]
Ub-428-UBC(381-456) [mitochondrial outer membrane]
Ub-48-UBC(1-76) [mitochondrial outer membrane]
Ub-504-UBC(457-532) [mitochondrial outer membrane]
Ub-200-UBC(153-228) [mitochondrial outer membrane]
Ub-580-UBC(533-608) [mitochondrial outer membrane]
Ub-276-UBC(229-304) [mitochondrial outer membrane]
Ub-352-UBC(305-380) [mitochondrial outer membrane]
Ub-29-UBC(1-76) [mitochondrial outer membrane]
Ub-182-UBC(153-228) [mitochondrial outer membrane]
Ub-486-UBC(457-532) [mitochondrial outer membrane]
Ub-334-UBC(305-380) [mitochondrial outer membrane]
Ub-638-UBC(609-684) [mitochondrial outer membrane]
Ub-106-UBC(77-152) [mitochondrial outer membrane]
Ub-258-UBC(229-304) [mitochondrial outer membrane]
Ub-562-UBC(533-608) [mitochondrial outer membrane]
Ub-410-UBC(381-456) [mitochondrial outer membrane]
Ub-636-UBC(609-684) [mitochondrial outer membrane]
Ub-104-UBC(77-152) [mitochondrial outer membrane]
Ub-256-UBC(229-304) [mitochondrial outer membrane]
Ub-484-UBC(457-532) [mitochondrial outer membrane]
Ub-27-UBC(1-76) [mitochondrial outer membrane]
Ub-332-UBC(305-380) [mitochondrial outer membrane]
Ub-180-UBC(153-228) [mitochondrial outer membrane]
Ub-408-UBC(381-456) [mitochondrial outer membrane]
Ub-560-UBC(533-608) [mitochondrial outer membrane]
N6-glycyl-L-lysine-UBC(457-532) [cytosol]
N6-glycyl-L-lysine-UBC(609-684) [cytosol]
N6-glycyl-L-lysine-UBC(229-304) [cytosol]
N6-glycyl-L-lysine-UBC(533-608) [cytosol]
N6-glycyl-L-lysine-UBC(153-228) [cytosol]
N6-glycyl-L-lysine-UBC(305-380) [cytosol]
N6-glycyl-L-lysine-UBC(77-152) [cytosol]
N6-glycyl-L-lysine-UBC(1-76) [cytosol]
N6-glycyl-L-lysine-UBC(381-456) [cytosol]
Ub-29-UBC(1-76) [cytosol]
Ub-258-UBC(229-304) [cytosol]
Ub-334-UBC(305-380) [cytosol]
Ub-410-UBC(381-456) [cytosol]
Ub-486-UBC(457-532) [cytosol]
Ub-562-UBC(533-608) [cytosol]
Ub-106-UBC(77-152) [cytosol]
Ub-182-UBC(153-228) [cytosol]
Ub-638-UBC(609-684) [cytosol]
Ub-310-UBC(305-380) [cytosol]
Ub-6-UBC(1-76) [cytosol]
Ub-462-UBC(457-532) [cytosol]
Ub-386-UBC(381-456) [cytosol]
Ub-538-UBC(533-608) [cytosol]
Ub-158-UBC(153-228) [cytosol]
Ub-614-UBC(609-684) [cytosol]
Ub-234-UBC(229-304) [cytosol]
Ub-82-UBC(77-152) [cytosol]
Ub-110-UBC(77-152) [cytosol]
Ub-33-UBC(1-76) [cytosol]
Ub-488-UBC(457-532) [cytosol]
Ub-338-UBC(305-380) [cytosol]
Ub-642-UBC(609-684) [cytosol]
Ub-414-UBC(381-456) [cytosol]
Ub-262-UBC(229-304) [cytosol]
Ub-566-UBC(533-608) [cytosol]
Ub-186-UBC(153-228) [cytosol]
phospho-adenylatedG608-UBC(533-608) [nucleoplasm]
phospho-adenylatedG380-UBC(305-380) [nucleoplasm]
phospho-adenylatedG532-UBC(457-532) [nucleoplasm]
phospho-adenylatedG304-UBC(229-304) [nucleoplasm]
phospho-adenylatedG152-UBC(77-152) [nucleoplasm]
phospho-adenylatedG684-UBC(609-684) [nucleoplasm]
phospho-adenylatedG228-UBC(153-228) [nucleoplasm]
phospho-adenylatedG76-UBC(1-76) [nucleoplasm]
phospho-adenylatedG456-UBC(381-456) [nucleoplasm]
UBC [cytosol]
phospho-adenylatedG380-UBC(305-380) [cytosol]
phospho-adenylatedG608-UBC(533-608) [cytosol]
phospho-adenylatedG76-UBC(1-76) [cytosol]
phospho-adenylatedG304-UBC(229-304) [cytosol]
phospho-adenylatedG684-UBC(609-684) [cytosol]
phospho-adenylatedG152-UBC(77-152) [cytosol]
phospho-adenylatedG532-UBC(457-532) [cytosol]
phospho-adenylatedG228-UBC(153-228) [cytosol]
phospho-adenylatedG456-UBC(381-456) [cytosol]
ISG15 [nucleoplasm]
K164-PCNA-G157-ISG15 [nucleoplasm]
UBC(1-76) [endosome membrane]
UBC(533-608) [endosome membrane]
UBC(77-152) [endosome membrane]
UBC(305-380) [endosome membrane]
UBC(457-532) [endosome membrane]
UBC(381-456) [endosome membrane]
UBC(153-228) [endosome membrane]
UBC(609-684) [endosome membrane]
UBC(229-304) [endosome membrane]
ISG15 [cytosol]
Ub-256-UBC(229-304) [cytosol]
Ub-180-UBC(153-228) [cytosol]
Ub-104-UBC(77-152) [cytosol]
Ub-484-UBC(457-532) [cytosol]
Ub-560-UBC(533-608) [cytosol]
Ub-636-UBC(609-684) [cytosol]
Ub-332-UBC(305-380) [cytosol]
Ub-27-UBC(1-76) [cytosol]
Ub-408-UBC(381-456) [cytosol]
Ub-87-UBC(77-152) [cytosol]
Ub-163-UBC(153-228) [cytosol]
Ub-619-UBC(609-684) [cytosol]
Ub-467-UBC(457-532) [cytosol]
Ub-11-UBC(1-76) [cytosol]
Ub-543-UBC(533-608) [cytosol]
Ub-391-UBC(381-456) [cytosol]
Ub-315-UBC(305-380) [cytosol]
Ub-239-UBC(229-304) [cytosol]
Ub-408-UBC(381-456) [nucleoplasm]
Ub-484-UBC(457-532) [nucleoplasm]
Ub-104-UBC(77-152) [nucleoplasm]
Ub-256-UBC(229-304) [nucleoplasm]
Ub-180-UBC(153-228) [nucleoplasm]
Ub-560-UBC(533-608) [nucleoplasm]
Ub-27-UBC(1-76) [nucleoplasm]
Ub-636-UBC(609-684) [nucleoplasm]
Ub-332-UBC(305-380) [nucleoplasm]
Ub-638-UBC(609-684) [nucleoplasm]
Ub-258-UBC(229-304) [nucleoplasm]
Ub-562-UBC(533-608) [nucleoplasm]
Ub-410-UBC(381-456) [nucleoplasm]
Ub-182-UBC(153-228) [nucleoplasm]
Ub-106-UBC(77-152) [nucleoplasm]
Ub-334-UBC(305-380) [nucleoplasm]
Ub-29-UBC(1-76) [nucleoplasm]
Ub-486-UBC(457-532) [nucleoplasm]
Ub-48-UBC(1-76) [nucleoplasm]
Ub-428-UBC(381-456) [nucleoplasm]
Ub-504-UBC(457-532) [nucleoplasm]
Ub-276-UBC(229-304) [nucleoplasm]
Ub-200-UBC(153-228) [nucleoplasm]
Ub-656-UBC(609-684) [nucleoplasm]
Ub-580-UBC(533-608) [nucleoplasm]
Ub-124-UBC(77-152) [nucleoplasm]
Ub-352-UBC(305-380) [nucleoplasm]
Ub-467-UBC(457-532) [nucleoplasm]
Ub-163-UBC(153-228) [nucleoplasm]
Ub-11-UBC(1-76) [nucleoplasm]
Ub-87-UBC(77-152) [nucleoplasm]
Ub-239-UBC(229-304) [nucleoplasm]
Ub-543-UBC(533-608) [nucleoplasm]
Ub-391-UBC(381-456) [nucleoplasm]
Ub-315-UBC(305-380) [nucleoplasm]
Ub-619-UBC(609-684) [nucleoplasm]
Ub-186-UBC(153-228) [nucleoplasm]
Ub-338-UBC(305-380) [nucleoplasm]
Ub-33-UBC(1-76) [nucleoplasm]
Ub-110-UBC(77-152) [nucleoplasm]
Ub-262-UBC(229-304) [nucleoplasm]
Ub-642-UBC(609-684) [nucleoplasm]
Ub-566-UBC(533-608) [nucleoplasm]
Ub-414-UBC(381-456) [nucleoplasm]
Ub-488-UBC(457-532) [nucleoplasm]
Ub-82-UBC(77-152) [nucleoplasm]
Ub-6-UBC(1-76) [nucleoplasm]
Ub-234-UBC(229-304) [nucleoplasm]
Ub-158-UBC(153-228) [nucleoplasm]
Ub-310-UBC(305-380) [nucleoplasm]
Ub-538-UBC(533-608) [nucleoplasm]
Ub-462-UBC(457-532) [nucleoplasm]
Ub-386-UBC(381-456) [nucleoplasm]
Ub-614-UBC(609-684) [nucleoplasm]
UBC(229-304) [nucleoplasm]
UBC(381-456) [nucleoplasm]
UBC(305-380) [nucleoplasm]
UBC(457-532) [nucleoplasm]
UBC(533-608) [nucleoplasm]
UBC(77-152) [nucleoplasm]
UBC(609-684) [nucleoplasm]
UBC(1-76) [nucleoplasm]
UBC(153-228) [nucleoplasm]
Ub-671-UBC(609-684) [nucleoplasm]
Ub-139-UBC(77-152) [nucleoplasm]
Ub-519-UBC(457-532) [nucleoplasm]
Ub-63-UBC(1-76) [nucleoplasm]
Ub-595-UBC(533-608) [nucleoplasm]
Ub-215-UBC(153-228) [nucleoplasm]
Ub-443-UBC(381-456) [nucleoplasm]
Ub-291-UBC(229-304) [nucleoplasm]
Ub-367-UBC(305-380) [nucleoplasm]
Ub-48-UBC(1-76) [cytosol]
Ub-656-UBC(609-684) [cytosol]
Ub-428-UBC(381-456) [cytosol]
Ub-504-UBC(457-532) [cytosol]
Ub-580-UBC(533-608) [cytosol]
Ub-276-UBC(229-304) [cytosol]
Ub-443-UBC(381-456) [cytosol]
Ub-519-UBC(457-532) [cytosol]
Ub-63-UBC(1-76) [cytosol]
Ub-671-UBC(609-684) [cytosol]
Ub-367-UBC(305-380) [cytosol]
Ub-291-UBC(229-304) [cytosol]
Ub-595-UBC(533-608) [cytosol]
Ub-215-UBC(153-228) [cytosol]
UBC(533-608) [cytosol]
UBC(305-380) [cytosol]
UBC(77-152) [cytosol]
UBC(609-684) [cytosol]
UBC(153-228) [cytosol]
UBC(229-304) [cytosol]
UBC(381-456) [cytosol]
UBC(1-76) [cytosol]
UBC(457-532) [cytosol]
Ub-352-UBC(305-380) [cytosol]
Ub-200-UBC(153-228) [cytosol]
Ub-124-UBC(77-152) [cytosol]
Inferred From
Ub-139-UBC(77-152) [cytosol] (Homo sapiens)
Modified Residues
Name
ubiquitinylated lysine at 139 (in Homo sapiens)
Coordinate
139
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
RefSeq
NP_727078.1
,
NP_001284937.1
Flybase
FBgn0086558
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