Ncd is a dimer

Stable Identifier
R-DME-990504
Type
Reaction [binding]
Species
Drosophila melanogaster
Compartment
General
SVG |   | PPTX  | SBGN
Ncd is a dimer

Ncd is a minus-end-directed kinesin. Cooperative interactions between the motor heads in the active dimer influence the interactions of each respective motor domain with the microtubule. These interactions are required for ATP-dependent dissociation; one function of the partner motor domain may be to weaken the interaction of the adjacent head with the microtubule (Mackey & Gilbert 2000).

Literature References
PubMed ID Title Journal Year
10574799 The crystal structure of the minus-end-directed microtubule motor protein ncd reveals variable dimer conformations

Kozielski, F, De Bonis, S, Burmeister, WP, Cohen-Addad, C, Wade, RH

Structure 1999
Participants
Orthologous Events
Authored
Reviewed
Created