Reactome | Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer [plasma membrane]

Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer [plasma membrane]

Stable Identifier

R-DRE-1168898

Type

Complex

Species

Danio rerio

Compartment

plasma membrane

Locations in the PathwayBrowser

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General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

Growth Hormone [extracellular region] (Danio rerio)
Tyrosine phosphorylated Growth Hormone Receptor:p(Y1007)-JAK2 dimer [plasma membrane] (Danio rerio)

Participates

as an output of

p-STAT5A/B dissociates from the Growth Hormone receptor (Danio rerio)
JAK2 phosphorylation of GHR (Danio rerio)

as a component of

Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer:SHP2 [plasma membrane] (Danio rerio)
Growth Hormone:Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer:p-STAT5 [plasma membrane] (Danio rerio)

Inferred From

Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)

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