Reactome | rnps1 [cytosol]

rnps1 [cytosol]

Stable Identifier

R-DRE-159256

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

cytosol

Synonyms

RNPS1, Q6PG31

Locations in the PathwayBrowser

Expand all

Metabolism of RNA (Danio rerio)

- Nonsense-Mediated Decay (NMD) (Danio rerio)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Danio rerio)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Danio rerio)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Danio rerio)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Danio rerio)
        
        Exon Junction:UPF2:UPF3 Complex [cytosol] (Danio rerio)
        
        rnps1 [cytosol] (Danio rerio)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Danio rerio)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Danio rerio)
        
        Exon Junction:UPF2:UPF3 Complex [cytosol] (Danio rerio)
        
        rnps1 [cytosol] (Danio rerio)
    - SMG6 hydrolyzes mRNA with premature termination codon (Danio rerio)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Danio rerio)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Danio rerio)
        
        Exon Junction:UPF2:UPF3 Complex [cytosol] (Danio rerio)
        
        rnps1 [cytosol] (Danio rerio)
    - p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A (Danio rerio)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Danio rerio)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Danio rerio)
        
        Exon Junction:UPF2:UPF3 Complex [cytosol] (Danio rerio)
        
        rnps1 [cytosol] (Danio rerio)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Danio rerio)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Danio rerio)
        
        Exon Junction:UPF2:UPF3 Complex [cytosol] (Danio rerio)
        
        rnps1 [cytosol] (Danio rerio)

External Reference Information

External Reference

UniProt:Q6PG31

Gene Names

rnps1

Reference Genes

BioGPS Gene:327020 rnps1

ENSEMBL:ENSDARG00000116743

KEGG Gene (Danio rerio):103909923 rnps1

KEGG Gene (Danio rerio):327020 rnps1

Monarch:327020 rnps1

NCBI Gene:327020 rnps1

Reference Transcript

Participates

as a component of

Exon Junction:UPF2:UPF3 Complex [cytosol] (Danio rerio)

Other forms of this molecule

rnps1 [nucleoplasm]

Inferred From

RNPS1 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_009296550.1, NP_956055.1

ZFIN

ZDB-GENE-030131-5228

PRO

Q6PG31

Cite Us!