Reactome | zgc:76966 [cytosol]

zgc:76966 [cytosol]

Stable Identifier

R-DRE-162411

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

cytosol

Synonyms

TRIB3, Q6NY44

Locations in the PathwayBrowser

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Signal Transduction (Danio rerio)

- Signaling by Receptor Tyrosine Kinases (Danio rerio)
  - Signaling by Insulin receptor (Danio rerio)
    - Insulin receptor signalling cascade (Danio rerio)
      - IRS-mediated signalling (Danio rerio)
        
        PI3K Cascade (Danio rerio)
        
        Activation of AKT2 (Danio rerio)
        
        AKT2 binds PIP3 (Danio rerio)
        
        AKT2:THEM4,TRIB3 [cytosol] (Danio rerio)
        
        zgc:76966 [cytosol] (Danio rerio)
        
        zgc:76966 [cytosol] (Danio rerio)
  - Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Danio rerio)
    - IGF1R signaling cascade (Danio rerio)
      - IRS-related events triggered by IGF1R (Danio rerio)
        
        IRS-mediated signalling (Danio rerio)
        
        PI3K Cascade (Danio rerio)
        
        Activation of AKT2 (Danio rerio)
        
        AKT2 binds PIP3 (Danio rerio)
        
        AKT2:THEM4,TRIB3 [cytosol] (Danio rerio)
        
        zgc:76966 [cytosol] (Danio rerio)
        
        zgc:76966 [cytosol] (Danio rerio)

External Reference Information

External Reference

UniProt:Q6NY44

Gene Names

zgc:76966

Reference Genes

BioGPS Gene:405805 zgc:76966

ENSEMBL:ENSDARG00000016200

KEGG Gene (Danio rerio):405805 zgc:76966

Monarch:405805 zgc:76966

NCBI Gene:405805 zgc:76966

Reference Transcript

RefSeq:NM_212869.1 zgc:76966

Participates

as an output of

AKT2 binds PIP3 (Danio rerio)

as a component of

AKT2:THEM4,TRIB3 [cytosol] (Danio rerio)

Other forms of this molecule

zgc:76966 [plasma membrane]

Inferred From

THEM4,TRIB3 [cytosol] (Homo sapiens)

TRIB3 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_998034.1

ZFIN

ZDB-GENE-040426-2609

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