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xx:ai39657 [extracellular region]
Stable Identifier
R-DRE-170838
Type
Protein [EntityWithAccessionedSequence]
Species
Danio rerio
Compartment
extracellular region
Synonyms
TGFB1, Q7ZZU7
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Danio rerio)
Non-integrin membrane-ECM interactions (Danio rerio)
Syndecan interactions (Danio rerio)
Syndecans 2, (4) bind TGFB1 (Danio rerio)
Syndecans 2, (4):TGFB1 [plasma membrane] (Danio rerio)
xx:ai39657 [extracellular region] (Danio rerio)
xx:ai39657 [extracellular region] (Danio rerio)
Gene expression (Transcription) (Danio rerio)
RNA Polymerase II Transcription (Danio rerio)
Generic Transcription Pathway (Danio rerio)
Transcriptional regulation by RUNX3 (Danio rerio)
RUNX3 regulates CDKN1A transcription (Danio rerio)
RUNX3 binds ZFHX3 (Danio rerio)
Dimeric TGFB1 [extracellular region] (Danio rerio)
xx:ai39657 [extracellular region] (Danio rerio)
Regulation of RUNX3 expression and activity (Danio rerio)
RUNX3 translocates to the nucleus (Danio rerio)
Dimeric TGFB1 [extracellular region] (Danio rerio)
xx:ai39657 [extracellular region] (Danio rerio)
Hemostasis (Danio rerio)
Platelet activation, signaling and aggregation (Danio rerio)
Response to elevated platelet cytosolic Ca2+ (Danio rerio)
Platelet degranulation (Danio rerio)
Exocytosis of platelet alpha granule contents (Danio rerio)
Platelet alpha granule contents [extracellular region] (Danio rerio)
TGF beta [extracellular region] (Danio rerio)
xx:ai39657 [extracellular region] (Danio rerio)
Signal Transduction (Danio rerio)
Signaling by TGFB family members (Danio rerio)
Signaling by TGF-beta Receptor Complex (Danio rerio)
TGF-beta receptor signaling activates SMADs (Danio rerio)
Activated type I receptor phosphorylates SMAD2/3 directly (Danio rerio)
TGFB1:p-TGFBR:ZFYVE9:SMAD2/3 [early endosome membrane] (Danio rerio)
Dimeric TGFB1 [extracellular region] (Danio rerio)
xx:ai39657 [extracellular region] (Danio rerio)
TGFB1:p-TGFBR:ZFYVE9:p-2S-SMAD2,3 [early endosome membrane] (Danio rerio)
Dimeric TGFB1 [extracellular region] (Danio rerio)
xx:ai39657 [extracellular region] (Danio rerio)
An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3 (Danio rerio)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Danio rerio)
Dimeric TGFB1 [extracellular region] (Danio rerio)
xx:ai39657 [extracellular region] (Danio rerio)
TGFB1:p-TGFBR:ZFYVE9:SMAD2/3 [early endosome membrane] (Danio rerio)
Dimeric TGFB1 [extracellular region] (Danio rerio)
xx:ai39657 [extracellular region] (Danio rerio)
Dimeric TGF-beta-1 binds to the receptor (Danio rerio)
Dimeric TGFB1 [extracellular region] (Danio rerio)
xx:ai39657 [extracellular region] (Danio rerio)
Dimeric TGFB1:TGFBR2 homodimer [plasma membrane] (Danio rerio)
Dimeric TGFB1 [extracellular region] (Danio rerio)
xx:ai39657 [extracellular region] (Danio rerio)
TGFB1,TGFB2:TGFBR3:TGFBR2 [plasma membrane] (Danio rerio)
TGFB1,TGFB2:TGFBR3 [plasma membrane] (Danio rerio)
TGFB1,TGFB2 [extracellular region] (Danio rerio)
xx:ai39657 [extracellular region] (Danio rerio)
TGFBR3(1-783):TGFB1,TGFB2 [extracellular region] (Danio rerio)
TGFB1,TGFB2 [extracellular region] (Danio rerio)
xx:ai39657 [extracellular region] (Danio rerio)
Downregulation of TGF-beta receptor signaling (Danio rerio)
BAMBI interferes with the interaction of type I receptor with type II receptor (Danio rerio)
TGFB1: TGFBR2: p-TGFBR1: BAMBI: SMAD7 [plasma membrane] (Danio rerio)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Danio rerio)
Dimeric TGFB1 [extracellular region] (Danio rerio)
xx:ai39657 [extracellular region] (Danio rerio)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Danio rerio)
Dimeric TGFB1 [extracellular region] (Danio rerio)
xx:ai39657 [extracellular region] (Danio rerio)
Degradation of TGF-beta receptor complex (Danio rerio)
TGFB1:TGFBR2:Ub-p-TGFBR1:Ub-SMAD7 [plasma membrane] (Danio rerio)
TGFB1: p-TGFBR: I-SMAD7 [plasma membrane] (Danio rerio)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Danio rerio)
Dimeric TGFB1 [extracellular region] (Danio rerio)
xx:ai39657 [extracellular region] (Danio rerio)
I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1) (Danio rerio)
TGFB1: p-TGFBR: I-SMAD7 [plasma membrane] (Danio rerio)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Danio rerio)
Dimeric TGFB1 [extracellular region] (Danio rerio)
xx:ai39657 [extracellular region] (Danio rerio)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Danio rerio)
Dimeric TGFB1 [extracellular region] (Danio rerio)
xx:ai39657 [extracellular region] (Danio rerio)
STRAP stabilizes interaction of activated TGF-beta receptor complex with SMAD7 (Danio rerio)
TGFB1: p-TGFBR: STRAP: SMAD7 [plasma membrane] (Danio rerio)
TGFB1:p-TGFBR:STRAP [plasma membrane] (Danio rerio)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Danio rerio)
Dimeric TGFB1 [extracellular region] (Danio rerio)
xx:ai39657 [extracellular region] (Danio rerio)
TGFB1:p-TGFBR:STRAP [plasma membrane] (Danio rerio)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Danio rerio)
Dimeric TGFB1 [extracellular region] (Danio rerio)
xx:ai39657 [extracellular region] (Danio rerio)
Phosphorylated SMAD2/3 dissociates from TGFBR (Danio rerio)
TGFB1:p-TGFBR:ZFYVE9 [early endosome membrane] (Danio rerio)
Dimeric TGFB1 [extracellular region] (Danio rerio)
xx:ai39657 [extracellular region] (Danio rerio)
TGFB1:p-TGFBR:ZFYVE9:p-2S-SMAD2,3 [early endosome membrane] (Danio rerio)
Dimeric TGFB1 [extracellular region] (Danio rerio)
xx:ai39657 [extracellular region] (Danio rerio)
Secretion and activation of the latent large complex of TGF-beta-1 (Danio rerio)
TGFB1:LAP1 [extracellular region] (Danio rerio)
Dimeric TGFB1 [extracellular region] (Danio rerio)
xx:ai39657 [extracellular region] (Danio rerio)
TGFBR2 phosphorylates TGFBR1 (Danio rerio)
TGFB1:TGFBR2:TGFBR1 [plasma membrane] (Danio rerio)
Dimeric TGFB1 [extracellular region] (Danio rerio)
xx:ai39657 [extracellular region] (Danio rerio)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Danio rerio)
Dimeric TGFB1 [extracellular region] (Danio rerio)
xx:ai39657 [extracellular region] (Danio rerio)
TGFBR2 recruits TGFBR1 (Danio rerio)
Dimeric TGFB1:TGFBR2 homodimer [plasma membrane] (Danio rerio)
Dimeric TGFB1 [extracellular region] (Danio rerio)
xx:ai39657 [extracellular region] (Danio rerio)
TGFB1,TGFB2:TGFBR3:TGFBR2 [plasma membrane] (Danio rerio)
TGFB1,TGFB2:TGFBR3 [plasma membrane] (Danio rerio)
TGFB1,TGFB2 [extracellular region] (Danio rerio)
xx:ai39657 [extracellular region] (Danio rerio)
TGFB1:TGFBR2:TGFBR1 [plasma membrane] (Danio rerio)
Dimeric TGFB1 [extracellular region] (Danio rerio)
xx:ai39657 [extracellular region] (Danio rerio)
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) (Danio rerio)
Disassembly of tight junctions (Danio rerio)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:Ub-RHOA:SMURF1 [cell junction] (Danio rerio)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA:SMURF1 [plasma membrane] (Danio rerio)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Danio rerio)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Danio rerio)
Dimeric TGFB1 [extracellular region] (Danio rerio)
xx:ai39657 [extracellular region] (Danio rerio)
SMURF1 binds phosphorylated PARD6A (Danio rerio)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Danio rerio)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Danio rerio)
Dimeric TGFB1 [extracellular region] (Danio rerio)
xx:ai39657 [extracellular region] (Danio rerio)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA:SMURF1 [plasma membrane] (Danio rerio)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Danio rerio)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Danio rerio)
Dimeric TGFB1 [extracellular region] (Danio rerio)
xx:ai39657 [extracellular region] (Danio rerio)
SMURF1 ubiquitinates RHOA (Danio rerio)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA:SMURF1 [plasma membrane] (Danio rerio)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Danio rerio)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Danio rerio)
Dimeric TGFB1 [extracellular region] (Danio rerio)
xx:ai39657 [extracellular region] (Danio rerio)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:Ub-RHOA:SMURF1 [cell junction] (Danio rerio)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA:SMURF1 [plasma membrane] (Danio rerio)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Danio rerio)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Danio rerio)
Dimeric TGFB1 [extracellular region] (Danio rerio)
xx:ai39657 [extracellular region] (Danio rerio)
External Reference Information
External Reference
UniProt:Q7ZZU7
Gene Names
xx:ai39657
Reference Genes
BioGPS Gene:359834 xx:ai39657
CTD Gene:359834 xx:ai39657
ENSEMBL:ENSDARG00000041502
KEGG Gene (Danio rerio):359834 xx:ai39657
Monarch:359834 xx:ai39657
NCBI Gene:359834 xx:ai39657
Reference Transcript
RefSeq:NM_182873.1 xx:ai39657
Participates
as a member of
TGF beta [extracellular region] (Danio rerio)
TGFB1,TGFB2 [extracellular region] (Danio rerio)
as an input of
Syndecans 2, (4) bind TGFB1 (Danio rerio)
as a component of
Syndecans 2, (4):TGFB1 [plasma membrane] (Danio rerio)
Dimeric TGFB1 [extracellular region] (Danio rerio)
Other forms of this molecule
xx:ai39657 [platelet alpha granule lumen]
xx:ai39657 [plasma membrane]
xx:ai39657 [Golgi lumen]
xx:ai39657 [Golgi lumen]
xx:ai39657 [Golgi lumen]
xx:ai39657 [extracellular region]
Inferred From
TGFB1 [extracellular region]
(Homo sapiens)
Cross References
RefSeq
NP_878293.1
ZFIN
ZDB-GENE-030618-1
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