Reactome | dlg4a [plasma membrane]

dlg4a [plasma membrane]

Stable Identifier

R-DRE-202135

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

plasma membrane

Synonyms

DLG4, F1QCS0

Locations in the PathwayBrowser

Expand all

Immune System (Danio rerio)

- Cytokine Signaling in Immune system (Danio rerio)
  - FLT3 Signaling (Danio rerio)
    - RAF/MAP kinase cascade (Danio rerio)
      - RAS GEFs promote RAS nucleotide exchange (Danio rerio)
        
        RAS GEFs [plasma membrane] (Danio rerio)
        
        Gly,D-Ser:L-Glu:GRIN1:GRIN2B NMDA receptor:RASGRF1 oligomer:CALM1:4xCa2+ [plasma membrane] (Danio rerio)
        
        Gly,D-Ser:L-Glu:GRIN1:GRIN2B NMDA receptors [plasma membrane] (Danio rerio)
        
        GRIN1:GRIN2B NMDA receptors:PSD proteins [plasma membrane] (Danio rerio)
        
        GRIN1:GRIN2B NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL:ACTN2 [plasma membrane] (Danio rerio)
        
        GRIN1:GRIN2B NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL [plasma membrane] (Danio rerio)
        
        GRIN1:GRIN2B NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Danio rerio)
        
        DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Danio rerio)
        
        dlg4a [plasma membrane] (Danio rerio)
        
        dlg4a [plasma membrane] (Danio rerio)

Neuronal System (Danio rerio)

- Protein-protein interactions at synapses (Danio rerio)
  - Synaptic adhesion-like molecules (Danio rerio)
    - PSD-95 binds NMDA receptor (Danio rerio)
      - NMDAR:PSD-95 [plasma membrane] (Danio rerio)
        
        dlg4a [plasma membrane] (Danio rerio)
      - dlg4a [plasma membrane] (Danio rerio)
    - SALM1 binds NMDA receptor (Danio rerio)
      - NMDAR:PSD-95 [plasma membrane] (Danio rerio)
        
        dlg4a [plasma membrane] (Danio rerio)
      - SALM1:NMDAR:PSD-95 [plasma membrane] (Danio rerio)
        
        NMDAR:PSD-95 [plasma membrane] (Danio rerio)
        
        dlg4a [plasma membrane] (Danio rerio)
    - SALMs 1-3 bind to PSD-95 family members (Danio rerio)
      - PSD-95 family [plasma membrane] (Danio rerio)
        
        dlg4a [plasma membrane] (Danio rerio)
      - SALMs 1-3:PSD-95 family [plasma membrane] (Danio rerio)
        
        PSD-95 family [plasma membrane] (Danio rerio)
        
        dlg4a [plasma membrane] (Danio rerio)
- Transmission across Chemical Synapses (Danio rerio)
  - Neurotransmitter receptors and postsynaptic signal transmission (Danio rerio)
    - Activation of NMDA receptors and postsynaptic events (Danio rerio)
      - Unblocking of NMDA receptors, glutamate binding and activation (Danio rerio)
        
        Ca2+ influx into the post-synaptic cell (Danio rerio)
        
        Gly,D-Ser:L-Glu:GRIN1:GRIN2 NMDA receptors [plasma membrane] (Danio rerio)
        
        GRIN1:GRIN2 NMDA receptors:PSD proteins [plasma membrane] (Danio rerio)
        
        GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL:ACTN2 [plasma membrane] (Danio rerio)
        
        GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL [plasma membrane] (Danio rerio)
        
        GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Danio rerio)
        
        DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Danio rerio)
        
        dlg4a [plasma membrane] (Danio rerio)
        
        dlg4a [plasma membrane] (Danio rerio)
        
        Membrane depolarization upon activation of Ca impermeable AMPA receptors (Danio rerio)
        
        Gly,D-Ser:L-Glu:GRIN1:GRIN2B NMDA receptors:p-T286-CaMKII dodecamer:CALM1:4xCa2+ [plasma membrane] (Danio rerio)
        
        Gly,D-Ser:L-Glu:GRIN1:GRIN2B NMDA receptors [plasma membrane] (Danio rerio)
        
        GRIN1:GRIN2B NMDA receptors:PSD proteins [plasma membrane] (Danio rerio)
        
        GRIN1:GRIN2B NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL:ACTN2 [plasma membrane] (Danio rerio)
        
        GRIN1:GRIN2B NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL [plasma membrane] (Danio rerio)
        
        GRIN1:GRIN2B NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Danio rerio)
        
        DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Danio rerio)
        
        dlg4a [plasma membrane] (Danio rerio)
        
        dlg4a [plasma membrane] (Danio rerio)
    - Activation of kainate receptors upon glutamate binding (Danio rerio)
      - Ionotropic activity of kainate receptors (Danio rerio)
        
        Activation of Ca-permeable Kainate Receptor (Danio rerio)
        
        Activation of Ca-permeable Kainate receptors (Danio rerio)
        
        Kainate receptor-glutamate complex [plasma membrane] (Danio rerio)
        
        Kainate Receptors [plasma membrane] (Danio rerio)
        
        GRIK 2 homomer [plasma membrane] (Danio rerio)
        
        GRIK2 interacting proteins [plasma membrane] (Danio rerio)
        
        dlg4a [plasma membrane] (Danio rerio)
        
        GRIK4 heteromer with GRIK1/2/3 [plasma membrane] (Danio rerio)
        
        GRIK4 interacting proteins [plasma membrane] (Danio rerio)
        
        dlg4a [plasma membrane] (Danio rerio)
        
        kainate receptor binds glutamate (Danio rerio)
        
        Kainate Receptors [plasma membrane] (Danio rerio)
        
        GRIK 2 homomer [plasma membrane] (Danio rerio)
        
        GRIK2 interacting proteins [plasma membrane] (Danio rerio)
        
        dlg4a [plasma membrane] (Danio rerio)
        
        GRIK4 heteromer with GRIK1/2/3 [plasma membrane] (Danio rerio)
        
        GRIK4 interacting proteins [plasma membrane] (Danio rerio)
        
        dlg4a [plasma membrane] (Danio rerio)
        
        Kainate receptor-glutamate complex [plasma membrane] (Danio rerio)
        
        Kainate Receptors [plasma membrane] (Danio rerio)
        
        GRIK 2 homomer [plasma membrane] (Danio rerio)
        
        GRIK2 interacting proteins [plasma membrane] (Danio rerio)
        
        dlg4a [plasma membrane] (Danio rerio)
        
        GRIK4 heteromer with GRIK1/2/3 [plasma membrane] (Danio rerio)
        
        GRIK4 interacting proteins [plasma membrane] (Danio rerio)
        
        dlg4a [plasma membrane] (Danio rerio)

Signal Transduction (Danio rerio)

- MAPK family signaling cascades (Danio rerio)
  - MAPK1/MAPK3 signaling (Danio rerio)
    - RAF/MAP kinase cascade (Danio rerio)
      - RAS GEFs promote RAS nucleotide exchange (Danio rerio)
        
        RAS GEFs [plasma membrane] (Danio rerio)
        
        Gly,D-Ser:L-Glu:GRIN1:GRIN2B NMDA receptor:RASGRF1 oligomer:CALM1:4xCa2+ [plasma membrane] (Danio rerio)
        
        Gly,D-Ser:L-Glu:GRIN1:GRIN2B NMDA receptors [plasma membrane] (Danio rerio)
        
        GRIN1:GRIN2B NMDA receptors:PSD proteins [plasma membrane] (Danio rerio)
        
        GRIN1:GRIN2B NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL:ACTN2 [plasma membrane] (Danio rerio)
        
        GRIN1:GRIN2B NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL [plasma membrane] (Danio rerio)
        
        GRIN1:GRIN2B NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Danio rerio)
        
        DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Danio rerio)
        
        dlg4a [plasma membrane] (Danio rerio)
        
        dlg4a [plasma membrane] (Danio rerio)
- Signaling by Rho GTPases (Danio rerio)
  - RHO GTPase Effectors (Danio rerio)
    - RHO GTPases activate CIT (Danio rerio)
      - CIT-3 binds DLG4 (Danio rerio)
        
        RHOA,RHOB,RHOC,RAC1:GTP:CIT-3:DLG4 [plasma membrane] (Danio rerio)
        
        dlg4a [plasma membrane] (Danio rerio)
        
        dlg4a [plasma membrane] (Danio rerio)

External Reference Information

External Reference

UniProt:F1QCS0

Gene Names

dlg4a

Reference Genes

ENSEMBL:ENSDARG00000041926

Other Identifiers

100000823

13210075

A_15_P364015

A_15_P443580

CUST_28902_PI428451953

DRER05891

ENSDART00000048432

ENSDART00000048432_1

ENSDART00000048432_2

GO:0003674

GO:0005515

GO:0005575

GO:0005886

GO:0007155

GO:0007267

GO:0007268

GO:0008150

GO:0008328

GO:0030054

GO:0031594

GO:0032991

GO:0034330

GO:0043005

GO:0043113

GO:0043226

GO:0061024

GO:0097113

GO:0097120

GO:0098609

GO:0098839

GO:0098970

XM_688228

Participant Of

hasComponent

hasMember

input

Other forms of this molecule

dlg4a [cytosol]

Inferred From

DLG4 [plasma membrane] (Homo sapiens)

Cross References

Ensembl

ENSDARP00000048431, ENSDARG00000041926, ENSDART00000048432

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